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• W2101041233 abstract "There is a growing interest in the use of patientreported outcomes in rheumatoid arthritis (RA) clinical trials as well as in clinical practice (1). More and more, patients actively participate in shared decision-making, and these processes require outcome measures that are relevant and understandable by patients (2). It has also been shown that many patient-reported outcomes can distinguish active treatments from control treatments as effectively as “objective” measures can (3–5). Most patient-reported outcomes data are much more easily collected than are joint counts or laboratory data (6). The American College of Rheumatology (ACR) core set of disease activity measures in RA clinical trials contains 3 patient-reported outcomes: patient’s global assessment of disease activity, pain, and physical function (7,8). However, the Outcome Measures in Rheumatology (OMERACT) initiative, which included “expert patient” representatives as workshop participants, recommended in 2006 that all trials should additionally include a measure of fatigue (9,10). This recommendation was endorsed by the European League Against Rheumatism (EULAR) and the ACR in their collaborative recommendations published in 2008 (11). One of the available instruments for measuring fatigue is the recently validated Bristol RA Fatigue (BRAF) questionnaire, which was designed to measure fatigue in all its dimensions (12). Other new and promising patient-reported outcomes include the Rheumatoid Arthritis Impact of Disease (RAID) questionnaire, which measures the patient’s perceived impact of RA on daily health (13), and the Routine Assessment of Patient Index Data 3 (RAPID-3), an index of 3 patient measures from the core set of disease activity measures in RA clinical trials (physical function, pain, and patient’s global assessment) that was designed for use in a busy clinical setting (14). Despite the growing interest in the development and use of patient-reported outcomes in the field of rheumatology, their interpretation is not always easy." @default.
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• W2101041233 date "2012-08-27" @default.
• W2101041233 modified "2023-09-23" @default.
• W2101041233 title "Patient's global assessment of disease activity: What are we measuring?" @default.
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• W2101041233 doi "https://doi.org/10.1002/art.34540" @default.
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