FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101133602> ?p ?o ?g. }

• W2101133602 endingPage "437" @default.
• W2101133602 startingPage "437" @default.
• W2101133602 abstract "1 , Joo-Cheol Park This study was aimed to elucidate the biological function of OD314 (Apin protein), which is related to ameloblast differentiation and amelogenesis. Apin protein, calcifying epithelial odontogenic (pindborg) tumors (CEOTs)-associated amyloid, were isolated from CEOTs, and has similar nucleotide sequences to OD314. We examined expression of the OD314 mRNA using in-situ hybridization during tooth develop- ment in mice. Expression of OD314 and several enamel matrix proteins were examined in the cultured ameloblast cell line up to 28 days by reverse transcription-polymerase chain reaction (RT-PCR) amplifica- tion. After inactivation and over-expression of the OD314 gene in ameloblast cell lines using U6 vector- driven RNA interference and CMV-OD314 construct, RT-PCR were performed to evaluate the effect of the OD314 during amelogenesis. The results were as follows: 1. In in-situ hybridization, OD314 mRNAs were more strongly expressed in ameloblast than odontoblast. 2. When ameloblast cells were cultured in the differentiation and mineralization medium for 28 days, the tuftelin mRNA expression was maintained from the beginning to day 14, and then gradually decreased to day 28. The expressions of amelogenin and enamelin were gradually decreased according to the ameloblast differentiation. 3. Inactivation of OD314 by U6-OD314 siRNA construct down-regulated the expression of OD314, MMP- 20, and tuftelin, whereas over-expression of OD314 by CMV-OD314 construct up-regulated the expression of OD314 and MMP-20 without change in tuftelin. These results suggest that OD314 is considered as an ameloblast-enriched gene and may play the impor- tant roles in ameloblast differentiation and mineralization. ABSTRACT" @default.
• W2101133602 created "2016-06-24" @default.
• W2101133602 creator A5019786769 @default.
• W2101133602 creator A5028001014 @default.
• W2101133602 creator A5032157949 @default.
• W2101133602 creator A5067619911 @default.
• W2101133602 creator A5078799548 @default.
• W2101133602 creator A5083681494 @default.
• W2101133602 creator A5086921217 @default.
• W2101133602 creator A5087182435 @default.
• W2101133602 date "2006-01-01" @default.
• W2101133602 modified "2023-09-26" @default.
• W2101133602 title "Expression and function of OD314, Apin protein during ameloblast differentiation and amelogenesis" @default.
• W2101133602 cites W1490966724 @default.
• W2101133602 cites W1971163872 @default.
• W2101133602 cites W1988438623 @default.
• W2101133602 cites W2006518478 @default.
• W2101133602 cites W2008566464 @default.
• W2101133602 cites W2012984935 @default.
• W2101133602 cites W2017659522 @default.
• W2101133602 cites W2020208578 @default.
• W2101133602 cites W2023864912 @default.
• W2101133602 cites W2025227325 @default.
• W2101133602 cites W2039848988 @default.
• W2101133602 cites W2042142377 @default.
• W2101133602 cites W2047413775 @default.
• W2101133602 cites W2052485937 @default.
• W2101133602 cites W2076815127 @default.
• W2101133602 cites W2092992429 @default.
• W2101133602 cites W2146900615 @default.
• W2101133602 cites W2162550366 @default.
• W2101133602 cites W2605844154 @default.
• W2101133602 cites W2606665612 @default.
• W2101133602 cites W579111795 @default.
• W2101133602 doi "https://doi.org/10.5395/jkacd.2006.31.6.437" @default.
• W2101133602 hasPublicationYear "2006" @default.
• W2101133602 type Work @default.
• W2101133602 sameAs 2101133602 @default.
• W2101133602 citedByCount "0" @default.
• W2101133602 crossrefType "journal-article" @default.
• W2101133602 hasAuthorship W2101133602A5019786769 @default.
• W2101133602 hasAuthorship W2101133602A5028001014 @default.
• W2101133602 hasAuthorship W2101133602A5032157949 @default.
• W2101133602 hasAuthorship W2101133602A5067619911 @default.
• W2101133602 hasAuthorship W2101133602A5078799548 @default.
• W2101133602 hasAuthorship W2101133602A5083681494 @default.
• W2101133602 hasAuthorship W2101133602A5086921217 @default.
• W2101133602 hasAuthorship W2101133602A5087182435 @default.
• W2101133602 hasConcept C104317684 @default.
• W2101133602 hasConcept C104392178 @default.
• W2101133602 hasConcept C105580179 @default.
• W2101133602 hasConcept C106434640 @default.
• W2101133602 hasConcept C142724271 @default.
• W2101133602 hasConcept C150194340 @default.
• W2101133602 hasConcept C153911025 @default.
• W2101133602 hasConcept C156887251 @default.
• W2101133602 hasConcept C199106506 @default.
• W2101133602 hasConcept C199343813 @default.
• W2101133602 hasConcept C2520015 @default.
• W2101133602 hasConcept C2779263046 @default.
• W2101133602 hasConcept C54355233 @default.
• W2101133602 hasConcept C71924100 @default.
• W2101133602 hasConcept C81439078 @default.
• W2101133602 hasConcept C86803240 @default.
• W2101133602 hasConcept C95444343 @default.
• W2101133602 hasConceptScore W2101133602C104317684 @default.
• W2101133602 hasConceptScore W2101133602C104392178 @default.
• W2101133602 hasConceptScore W2101133602C105580179 @default.
• W2101133602 hasConceptScore W2101133602C106434640 @default.
• W2101133602 hasConceptScore W2101133602C142724271 @default.
• W2101133602 hasConceptScore W2101133602C150194340 @default.
• W2101133602 hasConceptScore W2101133602C153911025 @default.
• W2101133602 hasConceptScore W2101133602C156887251 @default.
• W2101133602 hasConceptScore W2101133602C199106506 @default.
• W2101133602 hasConceptScore W2101133602C199343813 @default.
• W2101133602 hasConceptScore W2101133602C2520015 @default.
• W2101133602 hasConceptScore W2101133602C2779263046 @default.
• W2101133602 hasConceptScore W2101133602C54355233 @default.
• W2101133602 hasConceptScore W2101133602C71924100 @default.
• W2101133602 hasConceptScore W2101133602C81439078 @default.
• W2101133602 hasConceptScore W2101133602C86803240 @default.
• W2101133602 hasConceptScore W2101133602C95444343 @default.
• W2101133602 hasIssue "6" @default.
• W2101133602 hasLocation W21011336021 @default.
• W2101133602 hasOpenAccess W2101133602 @default.
• W2101133602 hasPrimaryLocation W21011336021 @default.
• W2101133602 hasRelatedWork W1994223078 @default.
• W2101133602 hasRelatedWork W2010136189 @default.
• W2101133602 hasRelatedWork W2056145075 @default.
• W2101133602 hasRelatedWork W2078470292 @default.
• W2101133602 hasRelatedWork W2132594991 @default.
• W2101133602 hasRelatedWork W2169265899 @default.
• W2101133602 hasRelatedWork W2205278657 @default.
• W2101133602 hasRelatedWork W2395349413 @default.
• W2101133602 hasRelatedWork W2416224051 @default.
• W2101133602 hasRelatedWork W2977738228 @default.
• W2101133602 hasVolume "31" @default.
• W2101133602 isParatext "false" @default.

• next