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• W2101135583 endingPage "4467" @default.
• W2101135583 startingPage "4463" @default.
• W2101135583 abstract "Envelope (E) protein genes sampled from populations of dengue 2 (DEN-2) virus in individual Aedes aegypti mosquitoes and in serum from dengue patients were copied to cDNA, cloned, and sequenced. The nucleotide sequences of the E genes in more than 70% of the clones differed from the consensus sequence for the corresponding virus population at up to 11 sites, and 24 of the 94 clones contained at least one stop codon. Virus populations recovered up to 2 years apart yielded clones with similar polymorphisms in the E gene. For one mosquito, the clones obtained fell into two genotypes. One group of sequences was closely related to those of viruses recovered from dengue patients in the same locality (Yangon, Myanmar) since 1995 and were classified as Asian 1 genotype. The second group were Cosmopolitan genotype viruses which were also circulating in Yangon in 2000 and which were related to DEN-2 viruses sampled from southern China in 1999. Finally, one clone was identified as a recombinant genome composed of portions of these two parental genotypes. This is the first report of recombinant and parental dengue viruses in a single host." @default.
• W2101135583 created "2016-06-24" @default.
• W2101135583 creator A5007274879 @default.
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• W2101135583 creator A5086765462 @default.
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• W2101135583 date "2003-04-01" @default.
• W2101135583 modified "2023-10-18" @default.
• W2101135583 title "Diverse Dengue Type 2 Virus Populations Contain Recombinant and Both Parental Viruses in a Single Mosquito Host" @default.
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• W2101135583 doi "https://doi.org/10.1128/jvi.77.7.4463-4467.2003" @default.
• W2101135583 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/150639" @default.
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