Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101156750> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2101156750 endingPage "51" @default.
- W2101156750 startingPage "48" @default.
- W2101156750 abstract "Malaria is one of the most important tropical diseases and the greatest cause of morbidity and mortality in India. The search for new antimalarial compounds has been necessitated by Plasmodium falciparum resistance to standard antimalarial drugs. Plants are important source of biologically active compounds and have potential for the development of novel antimalarial drugs. Since a number of alkaloids have been successfully used for the treatment of malaria since ancient time In this study the crude alkaloid extract of three young plants Carica papaya Linn. (Family: Caricaceae), Datura innoxia Mill. (Family: Solonaceae) and Ricinus communis Linn (Euphorbiaceae) were evaluated against Plasmodium falciparum 3D7. The mean inhibitory concentration (IC50), the mean cytotoxic concentration and the selectivity index were estimated. The cytotoxicity was estimated on Madin-Darby Canine Kidney (MDCK) cell line in maximum dose tested. The alkaloidal extract of C. papaya showed stronger antiplasmodial activity as compared to D. innoxia and R. communis, the IC50 values in the range of 28.35 to 93.17μg/mL. Results demonstrated alkaloids as the putative active compound showing promising antimalarial effect." @default.
- W2101156750 created "2016-06-24" @default.
- W2101156750 creator A5008825392 @default.
- W2101156750 creator A5009150026 @default.
- W2101156750 creator A5047057258 @default.
- W2101156750 creator A5057145718 @default.
- W2101156750 creator A5081471862 @default.
- W2101156750 date "2014-01-01" @default.
- W2101156750 modified "2023-09-24" @default.
- W2101156750 title "Anti-plasmodial potential of crude alkaloidal extract of three plants used in traditional medicine in India" @default.
- W2101156750 cites W1538764270 @default.
- W2101156750 cites W1942621392 @default.
- W2101156750 cites W1975121778 @default.
- W2101156750 cites W2020251171 @default.
- W2101156750 cites W2031673923 @default.
- W2101156750 cites W2034019135 @default.
- W2101156750 cites W2034486758 @default.
- W2101156750 cites W2056407708 @default.
- W2101156750 cites W2090536258 @default.
- W2101156750 cites W2099821573 @default.
- W2101156750 cites W2113875228 @default.
- W2101156750 cites W2114918609 @default.
- W2101156750 cites W2129410767 @default.
- W2101156750 cites W2134286981 @default.
- W2101156750 cites W2313860644 @default.
- W2101156750 cites W2465893030 @default.
- W2101156750 doi "https://doi.org/10.9790/3008-09564851" @default.
- W2101156750 hasPublicationYear "2014" @default.
- W2101156750 type Work @default.
- W2101156750 sameAs 2101156750 @default.
- W2101156750 citedByCount "1" @default.
- W2101156750 countsByYear W21011567502022 @default.
- W2101156750 crossrefType "journal-article" @default.
- W2101156750 hasAuthorship W2101156750A5008825392 @default.
- W2101156750 hasAuthorship W2101156750A5009150026 @default.
- W2101156750 hasAuthorship W2101156750A5047057258 @default.
- W2101156750 hasAuthorship W2101156750A5057145718 @default.
- W2101156750 hasAuthorship W2101156750A5081471862 @default.
- W2101156750 hasBestOaLocation W21011567501 @default.
- W2101156750 hasConcept C185592680 @default.
- W2101156750 hasConcept C556039675 @default.
- W2101156750 hasConcept C59822182 @default.
- W2101156750 hasConcept C71924100 @default.
- W2101156750 hasConcept C86803240 @default.
- W2101156750 hasConceptScore W2101156750C185592680 @default.
- W2101156750 hasConceptScore W2101156750C556039675 @default.
- W2101156750 hasConceptScore W2101156750C59822182 @default.
- W2101156750 hasConceptScore W2101156750C71924100 @default.
- W2101156750 hasConceptScore W2101156750C86803240 @default.
- W2101156750 hasIssue "5" @default.
- W2101156750 hasLocation W21011567501 @default.
- W2101156750 hasOpenAccess W2101156750 @default.
- W2101156750 hasPrimaryLocation W21011567501 @default.
- W2101156750 hasRelatedWork W1602224818 @default.
- W2101156750 hasRelatedWork W2027136333 @default.
- W2101156750 hasRelatedWork W2027989916 @default.
- W2101156750 hasRelatedWork W2047134548 @default.
- W2101156750 hasRelatedWork W2119976708 @default.
- W2101156750 hasRelatedWork W2468335957 @default.
- W2101156750 hasRelatedWork W2476588683 @default.
- W2101156750 hasRelatedWork W2981713487 @default.
- W2101156750 hasRelatedWork W3215139134 @default.
- W2101156750 hasRelatedWork W4240757957 @default.
- W2101156750 hasVolume "9" @default.
- W2101156750 isParatext "false" @default.
- W2101156750 isRetracted "false" @default.
- W2101156750 magId "2101156750" @default.
- W2101156750 workType "article" @default.