Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101163317> ?p ?o ?g. }
- W2101163317 abstract "Gambieric acid A (GAA) and its congeners belong to the family of marine polycyclic ether natural products. Their highly complex molecular architecture and unique biological activities have been of intense interest within the synthetic community. We have previously reported the first total synthesis, stereochemical reassignment, and preliminary structure-activity relationships of GAA. Here we disclose a concise synthesis of the A/BCD-ring fragment of GAA. The synthesis started from our previously reported synthetic intermediate that represents the A/B-ring. The C-ring was synthesized via an oxiranyl anion coupling and a 6-endo cyclization, and the D-ring was forged by means of an oxidative lactonization and subsequent palladium-catalyzed functionalization of the lactone ring. In this manner, the number of linear synthetic steps required for the construction of the C- and D-rings was reduced from 22 to 11." @default.
- W2101163317 created "2016-06-24" @default.
- W2101163317 creator A5019650603 @default.
- W2101163317 creator A5077476218 @default.
- W2101163317 creator A5084478484 @default.
- W2101163317 date "2015-01-13" @default.
- W2101163317 modified "2023-09-27" @default.
- W2101163317 title "Concise synthesis of the A/BCD-ring fragment of gambieric acid A" @default.
- W2101163317 cites W1526518230 @default.
- W2101163317 cites W1967355569 @default.
- W2101163317 cites W1968027485 @default.
- W2101163317 cites W1971178348 @default.
- W2101163317 cites W1971320547 @default.
- W2101163317 cites W1974286671 @default.
- W2101163317 cites W1977915889 @default.
- W2101163317 cites W1978890358 @default.
- W2101163317 cites W1989772178 @default.
- W2101163317 cites W1990170989 @default.
- W2101163317 cites W1996491925 @default.
- W2101163317 cites W2000340557 @default.
- W2101163317 cites W2000542817 @default.
- W2101163317 cites W2002467579 @default.
- W2101163317 cites W2004245896 @default.
- W2101163317 cites W2009111372 @default.
- W2101163317 cites W2011506606 @default.
- W2101163317 cites W2016098621 @default.
- W2101163317 cites W2021843948 @default.
- W2101163317 cites W2023985489 @default.
- W2101163317 cites W2029579061 @default.
- W2101163317 cites W2034313662 @default.
- W2101163317 cites W2035118130 @default.
- W2101163317 cites W2039672117 @default.
- W2101163317 cites W2043352235 @default.
- W2101163317 cites W2047013537 @default.
- W2101163317 cites W2047060522 @default.
- W2101163317 cites W2047247142 @default.
- W2101163317 cites W2049259357 @default.
- W2101163317 cites W2063352714 @default.
- W2101163317 cites W2072301028 @default.
- W2101163317 cites W2076020260 @default.
- W2101163317 cites W2077108639 @default.
- W2101163317 cites W2079258852 @default.
- W2101163317 cites W2082051207 @default.
- W2101163317 cites W2090391411 @default.
- W2101163317 cites W2096683187 @default.
- W2101163317 cites W2111118274 @default.
- W2101163317 cites W2128224905 @default.
- W2101163317 cites W2133347295 @default.
- W2101163317 cites W2142784405 @default.
- W2101163317 cites W2331800900 @default.
- W2101163317 cites W2803647709 @default.
- W2101163317 cites W2950030656 @default.
- W2101163317 cites W2950335123 @default.
- W2101163317 cites W2950350937 @default.
- W2101163317 cites W2951159760 @default.
- W2101163317 cites W2951225003 @default.
- W2101163317 cites W2951255889 @default.
- W2101163317 cites W2951473511 @default.
- W2101163317 cites W2951965741 @default.
- W2101163317 cites W2952393830 @default.
- W2101163317 cites W2952719059 @default.
- W2101163317 cites W2952791830 @default.
- W2101163317 cites W4233211793 @default.
- W2101163317 cites W4248692200 @default.
- W2101163317 doi "https://doi.org/10.3389/fchem.2014.00116" @default.
- W2101163317 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4292782" @default.
- W2101163317 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25629027" @default.
- W2101163317 hasPublicationYear "2015" @default.
- W2101163317 type Work @default.
- W2101163317 sameAs 2101163317 @default.
- W2101163317 citedByCount "3" @default.
- W2101163317 countsByYear W21011633172016 @default.
- W2101163317 countsByYear W21011633172017 @default.
- W2101163317 countsByYear W21011633172022 @default.
- W2101163317 crossrefType "journal-article" @default.
- W2101163317 hasAuthorship W2101163317A5019650603 @default.
- W2101163317 hasAuthorship W2101163317A5077476218 @default.
- W2101163317 hasAuthorship W2101163317A5084478484 @default.
- W2101163317 hasBestOaLocation W21011633171 @default.
- W2101163317 hasConcept C161904146 @default.
- W2101163317 hasConcept C178790620 @default.
- W2101163317 hasConcept C185592680 @default.
- W2101163317 hasConcept C21951064 @default.
- W2101163317 hasConcept C2776612806 @default.
- W2101163317 hasConcept C2780378348 @default.
- W2101163317 hasConcept C2780407432 @default.
- W2101163317 hasConcept C35753019 @default.
- W2101163317 hasConcept C71240020 @default.
- W2101163317 hasConceptScore W2101163317C161904146 @default.
- W2101163317 hasConceptScore W2101163317C178790620 @default.
- W2101163317 hasConceptScore W2101163317C185592680 @default.
- W2101163317 hasConceptScore W2101163317C21951064 @default.
- W2101163317 hasConceptScore W2101163317C2776612806 @default.
- W2101163317 hasConceptScore W2101163317C2780378348 @default.
- W2101163317 hasConceptScore W2101163317C2780407432 @default.
- W2101163317 hasConceptScore W2101163317C35753019 @default.
- W2101163317 hasConceptScore W2101163317C71240020 @default.
- W2101163317 hasLocation W21011633171 @default.
- W2101163317 hasLocation W21011633172 @default.
- W2101163317 hasLocation W21011633173 @default.