Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101178936> ?p ?o ?g. }
- W2101178936 endingPage "467" @default.
- W2101178936 startingPage "457" @default.
- W2101178936 abstract "The kinetics of transvascular fluid transport across fish capillaries and redistribution of fluids between intravascular compartments in intact fish are unknown. Cannulae were placed in the dorsal aorta (DA) and caudal vein (CV) of rainbow trout Oncorhynchus mykiss (mass 0.45-0.85 kg) and the fish spleenectomized. The following day a peristaltic pump was fitted to complete the extracorporeal arterio-venous circulation. Hematocrit (Hct) was monitored in unanesthetized fish either manually, by collecting blood from the extracorporeal loop at 5 min intervals for a period of 1 h (groups 1 and 2), or continuously (instantaneously) with an impedance flow-cell inserted in the aortic cannula (group 3). Fish in group 1 were volume expanded by injecting a volume of saline (0.9 g% NaCl; SI) or trout plasma (PI) equivalent to 40% of the plasma volume. In group 2, 20% or 35% of the blood volume was removed, and in group 3, 35% of the blood volume was removed. Plasma volume (Vp) was calculated from an assumed blood volume of 35 ml kg(-1) and the Hct. Vp declined mono-exponentially after SI with a half-time of 6.8 min and Vp reached a new steady state at 28.1 ml kg(-1); 30% of the injected volume remained in the vasculature. Volume recovery after PI was also mono-exponential, but slower (half-time=15.4 min) than SI, whereas the steady-state Vp (27.3 ml kg(-1)) was similar and 30% of the injected volume remained in the vasculature. Thus the presence of plasma proteins delayed fluid efflux from the vasculature, but did not affect the volume lost. Transvascular fluid filtration coefficients calculated from this data were 5.5 (SI) and 4.5 ml mmHg(-1) kg(-1) min(-1) (PI), and interstitial compliance was 11.8 (SI) and 9.7 ml mmHg(-1) kg(-1) (PI). The rate of volume recovery after 20% or 35% hemorrhage was independent of the hemorrhage volume (half-time=13.3 and 15.1 min, respectively) and similar to the half-time of PI, indicating that protein-rich interstitial fluid is returned to the vasculature. There is a nearly instantaneous change in Hct that occurs during the hemorrhage period; it is dependent on hemorrhage duration and volume and not associated with the subsequent mono-exponential recovery. This initial response is best explained by a rapid fluid shift from a large-volume (approximately 40% of total blood volume), low-hematocrit (less than half of systemic Hct) microcirculation into the higher-hematocrit macrocirculation. These studies are consistent with transcapillary fluid flux across a barrier that is highly permeable to protein, and cannot be explained by fluid shift between primary and secondary circulations, or by transcapilllary flux across a capillary bed that is impermeable to plasma proteins. The results support the hypothesis that whole-body reflection coefficients in trout are very low and that plasma oncotic pressure is not a determinant of transcapillary fluid balance. They also show that both transvascular and intravascular fluid movements are important effectors of central volume homeostasis." @default.
- W2101178936 created "2016-06-24" @default.
- W2101178936 creator A5012180340 @default.
- W2101178936 creator A5058635378 @default.
- W2101178936 creator A5069935336 @default.
- W2101178936 creator A5080942238 @default.
- W2101178936 date "2003-02-01" @default.
- W2101178936 modified "2023-10-18" @default.
- W2101178936 title "Transvascular and intravascular fluid transport in the rainbow trout:revisiting Starling's forces, the secondary circulation and interstitial compliance" @default.
- W2101178936 cites W1173227692 @default.
- W2101178936 cites W1484418640 @default.
- W2101178936 cites W1914074989 @default.
- W2101178936 cites W1952331511 @default.
- W2101178936 cites W1964918178 @default.
- W2101178936 cites W1969257865 @default.
- W2101178936 cites W2025566503 @default.
- W2101178936 cites W2041406132 @default.
- W2101178936 cites W2048984565 @default.
- W2101178936 cites W2060016730 @default.
- W2101178936 cites W2082779293 @default.
- W2101178936 cites W2152252562 @default.
- W2101178936 cites W2181049752 @default.
- W2101178936 cites W2187370142 @default.
- W2101178936 cites W2215830081 @default.
- W2101178936 cites W2253397333 @default.
- W2101178936 cites W2263680568 @default.
- W2101178936 cites W2281821380 @default.
- W2101178936 cites W2299585065 @default.
- W2101178936 cites W2327766637 @default.
- W2101178936 cites W2328940448 @default.
- W2101178936 cites W2404593519 @default.
- W2101178936 cites W2415365112 @default.
- W2101178936 cites W2523896876 @default.
- W2101178936 cites W4300444984 @default.
- W2101178936 cites W939022482 @default.
- W2101178936 cites W981120772 @default.
- W2101178936 doi "https://doi.org/10.1242/jeb.00123" @default.
- W2101178936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12502766" @default.
- W2101178936 hasPublicationYear "2003" @default.
- W2101178936 type Work @default.
- W2101178936 sameAs 2101178936 @default.
- W2101178936 citedByCount "41" @default.
- W2101178936 countsByYear W21011789362013 @default.
- W2101178936 countsByYear W21011789362014 @default.
- W2101178936 countsByYear W21011789362015 @default.
- W2101178936 countsByYear W21011789362017 @default.
- W2101178936 countsByYear W21011789362018 @default.
- W2101178936 countsByYear W21011789362019 @default.
- W2101178936 countsByYear W21011789362020 @default.
- W2101178936 countsByYear W21011789362021 @default.
- W2101178936 countsByYear W21011789362022 @default.
- W2101178936 countsByYear W21011789362023 @default.
- W2101178936 crossrefType "journal-article" @default.
- W2101178936 hasAuthorship W2101178936A5012180340 @default.
- W2101178936 hasAuthorship W2101178936A5058635378 @default.
- W2101178936 hasAuthorship W2101178936A5069935336 @default.
- W2101178936 hasAuthorship W2101178936A5080942238 @default.
- W2101178936 hasBestOaLocation W21011789361 @default.
- W2101178936 hasConcept C105702510 @default.
- W2101178936 hasConcept C126322002 @default.
- W2101178936 hasConcept C141071460 @default.
- W2101178936 hasConcept C185592680 @default.
- W2101178936 hasConcept C2778074680 @default.
- W2101178936 hasConcept C2779363728 @default.
- W2101178936 hasConcept C2780959883 @default.
- W2101178936 hasConcept C2909208804 @default.
- W2101178936 hasConcept C2994167347 @default.
- W2101178936 hasConcept C2994232697 @default.
- W2101178936 hasConcept C37557685 @default.
- W2101178936 hasConcept C505870484 @default.
- W2101178936 hasConcept C71924100 @default.
- W2101178936 hasConcept C86803240 @default.
- W2101178936 hasConceptScore W2101178936C105702510 @default.
- W2101178936 hasConceptScore W2101178936C126322002 @default.
- W2101178936 hasConceptScore W2101178936C141071460 @default.
- W2101178936 hasConceptScore W2101178936C185592680 @default.
- W2101178936 hasConceptScore W2101178936C2778074680 @default.
- W2101178936 hasConceptScore W2101178936C2779363728 @default.
- W2101178936 hasConceptScore W2101178936C2780959883 @default.
- W2101178936 hasConceptScore W2101178936C2909208804 @default.
- W2101178936 hasConceptScore W2101178936C2994167347 @default.
- W2101178936 hasConceptScore W2101178936C2994232697 @default.
- W2101178936 hasConceptScore W2101178936C37557685 @default.
- W2101178936 hasConceptScore W2101178936C505870484 @default.
- W2101178936 hasConceptScore W2101178936C71924100 @default.
- W2101178936 hasConceptScore W2101178936C86803240 @default.
- W2101178936 hasIssue "3" @default.
- W2101178936 hasLocation W21011789361 @default.
- W2101178936 hasLocation W21011789362 @default.
- W2101178936 hasOpenAccess W2101178936 @default.
- W2101178936 hasPrimaryLocation W21011789361 @default.
- W2101178936 hasRelatedWork W1976308001 @default.
- W2101178936 hasRelatedWork W2054379131 @default.
- W2101178936 hasRelatedWork W2138580168 @default.
- W2101178936 hasRelatedWork W2187293700 @default.
- W2101178936 hasRelatedWork W2322792069 @default.
- W2101178936 hasRelatedWork W2354055819 @default.
- W2101178936 hasRelatedWork W2372274602 @default.