FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101190659> ?p ?o ?g. }

• W2101190659 abstract "Genic DNA functions are commonplace: coding for proteins and specifying non-messenger RNA structure. Yet most DNA in the biosphere is non-genic, existing in nuclei as non-coding or secondary DNA. Why so much secondary DNA exists and why its amount per genome varies over orders of magnitude (correlating positively with cell volume) are central biological problems. A novel perspective on secondary DNA function comes from natural eukaryote eukaryote chimaeras (cryptomonads and chlorarachneans) where two phylogenetically distinct nuclei have coevolved within one cell for hundreds of millions of years. By comparing cryptomonad species differing 13-fold in cell volume, we show that nuclear and nucleomorph genome sizes obey fundamentally different scaling laws. Following a more than 125-fold reduction in DNA content, nucleomorph genomes exhibit little variation in size. Furthermore, the present lack of significant amounts of nucleomorph secondary DNA confirms that selection can readily eliminate functionless nuclear DNA, refuting 'selfish' and 'junk' theories of secondary DNA. Cryptomonad nuclear DNA content varied 12-fold: as in other eukaryotes, larger cells have extra DNA, which is almost certainly secondary DNA positively selected for a volume-related function. The skeletal DNA theory explains why nuclear genome size increases with cell volume and, using new evidence on nucleomorph gene functions, why nucleomorph genomes do not." @default.
• W2101190659 created "2016-06-24" @default.
• W2101190659 creator A5060439623 @default.
• W2101190659 creator A5088657040 @default.
• W2101190659 date "1999-10-22" @default.
• W2101190659 modified "2023-09-27" @default.
• W2101190659 title "Eukaryotic non-coding DNA is functional: evidence from the differential scaling of cryptomonad genomes" @default.
• W2101190659 cites W150415700 @default.
• W2101190659 cites W1765868291 @default.
• W2101190659 cites W1967035998 @default.
• W2101190659 cites W1967855171 @default.
• W2101190659 cites W1968434277 @default.
• W2101190659 cites W1971291340 @default.
• W2101190659 cites W1974884960 @default.
• W2101190659 cites W1995987924 @default.
• W2101190659 cites W1999237873 @default.
• W2101190659 cites W2004405458 @default.
• W2101190659 cites W2023401088 @default.
• W2101190659 cites W2030415964 @default.
• W2101190659 cites W2048203495 @default.
• W2101190659 cites W2048540261 @default.
• W2101190659 cites W2053539908 @default.
• W2101190659 cites W2055321471 @default.
• W2101190659 cites W2067800138 @default.
• W2101190659 cites W2069923353 @default.
• W2101190659 cites W2075613996 @default.
• W2101190659 cites W2084349698 @default.
• W2101190659 cites W2085154635 @default.
• W2101190659 cites W2086054261 @default.
• W2101190659 cites W2093660554 @default.
• W2101190659 cites W2131607521 @default.
• W2101190659 cites W2148591934 @default.
• W2101190659 cites W2325036902 @default.
• W2101190659 cites W2413227300 @default.
• W2101190659 cites W2441481898 @default.
• W2101190659 cites W4242499651 @default.
• W2101190659 doi "https://doi.org/10.1098/rspb.1999.0886" @default.
• W2101190659 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1690321" @default.
• W2101190659 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10902541" @default.
• W2101190659 hasPublicationYear "1999" @default.
• W2101190659 type Work @default.
• W2101190659 sameAs 2101190659 @default.
• W2101190659 citedByCount "46" @default.
• W2101190659 countsByYear W21011906592012 @default.
• W2101190659 countsByYear W21011906592021 @default.
• W2101190659 crossrefType "journal-article" @default.
• W2101190659 hasAuthorship W2101190659A5060439623 @default.
• W2101190659 hasAuthorship W2101190659A5088657040 @default.
• W2101190659 hasBestOaLocation W21011906592 @default.
• W2101190659 hasConcept C104317684 @default.
• W2101190659 hasConcept C115960442 @default.
• W2101190659 hasConcept C141231307 @default.
• W2101190659 hasConcept C24586158 @default.
• W2101190659 hasConcept C2779413310 @default.
• W2101190659 hasConcept C54355233 @default.
• W2101190659 hasConcept C552990157 @default.
• W2101190659 hasConcept C61271108 @default.
• W2101190659 hasConcept C64554109 @default.
• W2101190659 hasConcept C78458016 @default.
• W2101190659 hasConcept C86803240 @default.
• W2101190659 hasConceptScore W2101190659C104317684 @default.
• W2101190659 hasConceptScore W2101190659C115960442 @default.
• W2101190659 hasConceptScore W2101190659C141231307 @default.
• W2101190659 hasConceptScore W2101190659C24586158 @default.
• W2101190659 hasConceptScore W2101190659C2779413310 @default.
• W2101190659 hasConceptScore W2101190659C54355233 @default.
• W2101190659 hasConceptScore W2101190659C552990157 @default.
• W2101190659 hasConceptScore W2101190659C61271108 @default.
• W2101190659 hasConceptScore W2101190659C64554109 @default.
• W2101190659 hasConceptScore W2101190659C78458016 @default.
• W2101190659 hasConceptScore W2101190659C86803240 @default.
• W2101190659 hasLocation W21011906591 @default.
• W2101190659 hasLocation W21011906592 @default.
• W2101190659 hasLocation W21011906593 @default.
• W2101190659 hasLocation W21011906594 @default.
• W2101190659 hasOpenAccess W2101190659 @default.
• W2101190659 hasPrimaryLocation W21011906591 @default.
• W2101190659 hasRelatedWork W1515044983 @default.
• W2101190659 hasRelatedWork W1579785391 @default.
• W2101190659 hasRelatedWork W1582655487 @default.
• W2101190659 hasRelatedWork W1972815947 @default.
• W2101190659 hasRelatedWork W1979592281 @default.
• W2101190659 hasRelatedWork W2012393730 @default.
• W2101190659 hasRelatedWork W2038360379 @default.
• W2101190659 hasRelatedWork W2048203495 @default.
• W2101190659 hasRelatedWork W2048540261 @default.
• W2101190659 hasRelatedWork W2085154635 @default.
• W2101190659 hasRelatedWork W2086054261 @default.
• W2101190659 hasRelatedWork W2096978477 @default.
• W2101190659 hasRelatedWork W2109841945 @default.
• W2101190659 hasRelatedWork W2127982954 @default.
• W2101190659 hasRelatedWork W2131607361 @default.
• W2101190659 hasRelatedWork W2134681478 @default.
• W2101190659 hasRelatedWork W2148591934 @default.
• W2101190659 hasRelatedWork W2151777559 @default.
• W2101190659 hasRelatedWork W2159241461 @default.
• W2101190659 hasRelatedWork W2168909179 @default.
• W2101190659 isParatext "false" @default.
• W2101190659 isRetracted "false" @default.
• W2101190659 magId "2101190659" @default.

• next