FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101305223> ?p ?o ?g. }

• W2101305223 endingPage "1583" @default.
• W2101305223 startingPage "1579" @default.
• W2101305223 abstract "Binding of virus particles to specific host cell surface receptors is known to be an obligatory step in infection even though the molecular basis for these interactions is not well characterized. The crystal structure of the adenovirus fiber knob domain in complex with domain I of its human cellular receptor, coxsackie and adenovirus receptor (CAR), is presented here. Surface-exposed loops on knob contact one face of CAR, forming a high-affinity complex. Topology mismatches between interacting surfaces create interfacial solvent-filled cavities and channels that may be targets for antiviral drug therapy. The structure identifies key determinants of binding specificity, which may suggest ways to modify the tropism of adenovirus-based gene therapy vectors." @default.
• W2101305223 created "2016-06-24" @default.
• W2101305223 creator A5031129713 @default.
• W2101305223 creator A5031722637 @default.
• W2101305223 creator A5041168548 @default.
• W2101305223 creator A5071179644 @default.
• W2101305223 creator A5088323138 @default.
• W2101305223 date "1999-11-19" @default.
• W2101305223 modified "2023-10-14" @default.
• W2101305223 title "Structural Analysis of the Mechanism of Adenovirus Binding to Its Human Cellular Receptor, CAR" @default.
• W2101305223 cites W1539796472 @default.
• W2101305223 cites W1628484047 @default.
• W2101305223 cites W1680430286 @default.
• W2101305223 cites W1930355415 @default.
• W2101305223 cites W1964638756 @default.
• W2101305223 cites W1982327997 @default.
• W2101305223 cites W1995017064 @default.
• W2101305223 cites W1997559299 @default.
• W2101305223 cites W2004360551 @default.
• W2101305223 cites W2022939759 @default.
• W2101305223 cites W2023790301 @default.
• W2101305223 cites W2028231353 @default.
• W2101305223 cites W2049090751 @default.
• W2101305223 cites W2051758487 @default.
• W2101305223 cites W2068668309 @default.
• W2101305223 cites W2079805001 @default.
• W2101305223 cites W2091001090 @default.
• W2101305223 cites W2098781795 @default.
• W2101305223 cites W2106315897 @default.
• W2101305223 cites W2110680416 @default.
• W2101305223 cites W2116175479 @default.
• W2101305223 cites W2141373945 @default.
• W2101305223 doi "https://doi.org/10.1126/science.286.5444.1579" @default.
• W2101305223 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10567268" @default.
• W2101305223 hasPublicationYear "1999" @default.
• W2101305223 type Work @default.
• W2101305223 sameAs 2101305223 @default.
• W2101305223 citedByCount "410" @default.
• W2101305223 countsByYear W21013052232012 @default.
• W2101305223 countsByYear W21013052232013 @default.
• W2101305223 countsByYear W21013052232014 @default.
• W2101305223 countsByYear W21013052232015 @default.
• W2101305223 countsByYear W21013052232016 @default.
• W2101305223 countsByYear W21013052232017 @default.
• W2101305223 countsByYear W21013052232018 @default.
• W2101305223 countsByYear W21013052232019 @default.
• W2101305223 countsByYear W21013052232020 @default.
• W2101305223 countsByYear W21013052232021 @default.
• W2101305223 countsByYear W21013052232022 @default.
• W2101305223 countsByYear W21013052232023 @default.
• W2101305223 crossrefType "journal-article" @default.
• W2101305223 hasAuthorship W2101305223A5031129713 @default.
• W2101305223 hasAuthorship W2101305223A5031722637 @default.
• W2101305223 hasAuthorship W2101305223A5041168548 @default.
• W2101305223 hasAuthorship W2101305223A5071179644 @default.
• W2101305223 hasAuthorship W2101305223A5088323138 @default.
• W2101305223 hasBestOaLocation W21013052232 @default.
• W2101305223 hasConcept C104317684 @default.
• W2101305223 hasConcept C111599444 @default.
• W2101305223 hasConcept C114614502 @default.
• W2101305223 hasConcept C12554922 @default.
• W2101305223 hasConcept C1491633281 @default.
• W2101305223 hasConcept C159047783 @default.
• W2101305223 hasConcept C170493617 @default.
• W2101305223 hasConcept C174510640 @default.
• W2101305223 hasConcept C184720557 @default.
• W2101305223 hasConcept C2522874641 @default.
• W2101305223 hasConcept C2776954459 @default.
• W2101305223 hasConcept C33602714 @default.
• W2101305223 hasConcept C33923547 @default.
• W2101305223 hasConcept C35693153 @default.
• W2101305223 hasConcept C54355233 @default.
• W2101305223 hasConcept C70721500 @default.
• W2101305223 hasConcept C86803240 @default.
• W2101305223 hasConcept C95444343 @default.
• W2101305223 hasConceptScore W2101305223C104317684 @default.
• W2101305223 hasConceptScore W2101305223C111599444 @default.
• W2101305223 hasConceptScore W2101305223C114614502 @default.
• W2101305223 hasConceptScore W2101305223C12554922 @default.
• W2101305223 hasConceptScore W2101305223C1491633281 @default.
• W2101305223 hasConceptScore W2101305223C159047783 @default.
• W2101305223 hasConceptScore W2101305223C170493617 @default.
• W2101305223 hasConceptScore W2101305223C174510640 @default.
• W2101305223 hasConceptScore W2101305223C184720557 @default.
• W2101305223 hasConceptScore W2101305223C2522874641 @default.
• W2101305223 hasConceptScore W2101305223C2776954459 @default.
• W2101305223 hasConceptScore W2101305223C33602714 @default.
• W2101305223 hasConceptScore W2101305223C33923547 @default.
• W2101305223 hasConceptScore W2101305223C35693153 @default.
• W2101305223 hasConceptScore W2101305223C54355233 @default.
• W2101305223 hasConceptScore W2101305223C70721500 @default.
• W2101305223 hasConceptScore W2101305223C86803240 @default.
• W2101305223 hasConceptScore W2101305223C95444343 @default.
• W2101305223 hasIssue "5444" @default.
• W2101305223 hasLocation W21013052231 @default.
• W2101305223 hasLocation W21013052232 @default.
• W2101305223 hasLocation W21013052233 @default.
• W2101305223 hasOpenAccess W2101305223 @default.

• next