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• W2101412480 abstract "R adionuclide ventriculographic evaluation of left ventricular (LV] performance during exercise has shown that normal subjects manifest a slight increase in end-diastolic volume (Frank-Starling mechanism], a decrease in the end-systolic volume (increase in contractility] and an increase in the stroke volume [due to both mechanisms]. The increase in cardiac output is due to increases,in stroke volume and heart rate. There is improvement in the ejection fraction (EF]; the EF increases by 5% or more from rest to exercise depending on the EF at rest.1-4 An abnormality in LV response to exercise has been defined in terms of failure to augment the EF, appearance of wall motion abnormality or failure to decrease the end-systolic volume. Other less often used indexes include changes in pulmonary blood volume, pressure-volume relation and LV diastolic filling characteristics.5 The “normal” subjects who have been used to define the “normal” physiologic responses can be categorized into 3 types+ healthy volunteers, usually young and usually men; patients with a low pretest probability of coronary artery disease (CAD] based on clinical presentation and coronary risk factors; and patients with normal coronary arteriograms. Such patients are generally older and have troublesome or severe enough symptoms to warrant coronary arteriography. Coronary risk factors are more common in this group of patients.7 If normality can be viewed as a continuum rather than discrete, the healthy volunteers represent the" @default.
• W2101412480 created "2016-06-24" @default.
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• W2101412480 date "1987-11-01" @default.
• W2101412480 modified "2023-09-26" @default.
• W2101412480 title "Factors affecting exercise left ventricular performance in patients free of obstructive coronary artery disease" @default.
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• W2101412480 doi "https://doi.org/10.1016/0002-9149(87)90414-0" @default.
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