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• W2101446385 abstract "Current research into new drugs is focused on agents that will change multiple sclerosis process. MS14 is an herbal-marine product, based on anecdotal evidences in traditional Iranian medicine (TIM). The objective of this study was to assess the safety and efficacy of MS14 in volunteer patients. This study was a randomized placebo-controlled, double blind, crossover clinical trial in patients who had not responded to common MS drug regimens. Common toxicity criteria and quality of life (QOL) questionnaire were assessed. No significant changes were observed in vital signs, biochemical, hematological, liver and kidney function tests. Moreover, the improvement of patients' mobility (lower limb) was significant, comparison before treatment and placebo group (p-value: 0.048). These results suggest the potential benefits of MS14 on QOL in patients and attenuating and remodeling of multiple sclerosis disease and although the results confirm the safety and relative efficacy of MS14. Key words: Multiple sclerosis, MS14, Iranian traditional medicine." @default.
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• W2101446385 date "2009-04-30" @default.
• W2101446385 modified "2023-09-27" @default.
• W2101446385 title "A double blind, placebo-controlled, crossover study on the effect of MS14, an herbal-marine drug, on quality of life in patients with multiple sclerosis" @default.
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• W2101446385 doi "https://doi.org/10.5897/jmpr.9000011" @default.
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