Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101472021> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2101472021 endingPage "371" @default.
- W2101472021 startingPage "363" @default.
- W2101472021 abstract "The adenocarcinoma LT85 was chemically induced in a mouse from a C3Hf colony shown subsequently to be inbred for a gene conversion-like mutation at the H-2K locus, characterized by a clustered four nucleotide substitution in exon 3. The H-2K phenotype of LT85, however, more closely resembles that of C3H rather than the mutant strain now designated C3Hf H-2km2. We cloned and sequenced the H-2K gene from this tumor to determine whether (i) LT85 might carry a tumor-associated somatic reversion of the H-2Kkm2 germline mutation of (ii) the tumor was induced in a mouse that was genetically H-2k rather than H-2km2. Our analysis confirmed that the LT85 H-2K allele is identical throughout the entire coding region to C3H H-2Kk. To exclude the possibility of a somatic reversion by recombination, we used an oligonucleotide probe corresponding to the region altered in H-2k to show that the C3Hf genome lacks the necessary coding information to reverse the H-2Kkm2 mutation through a sequence exchange with another class I locus. Since it is unlikely that multiple independent point mutations would account for restoration of this stretch of H-2Kk sequences, the tumor was probably established in a mouse carrying a normal H-2Kk allele, possibly at a point prior to the establishment of the H-2Kkm2 mutation as a homozygous trait within the C3Hf colony." @default.
- W2101472021 created "2016-06-24" @default.
- W2101472021 creator A5028224790 @default.
- W2101472021 creator A5072880997 @default.
- W2101472021 creator A5087029063 @default.
- W2101472021 creator A5091556994 @default.
- W2101472021 date "1989-08-01" @default.
- W2101472021 modified "2023-09-24" @default.
- W2101472021 title "EVIDENCE THAT DERIVATION OF THE ADENOCARCINOMA LT85 PREDATED ESTABLISHMENT OF THE H‐2<sup>km2</sup> MUTATION IN A C3HF COLONY OF MICE" @default.
- W2101472021 cites W1483671702 @default.
- W2101472021 cites W1501041254 @default.
- W2101472021 cites W1515445925 @default.
- W2101472021 cites W1518632223 @default.
- W2101472021 cites W1557188763 @default.
- W2101472021 cites W1965908356 @default.
- W2101472021 cites W1969068077 @default.
- W2101472021 cites W1973291904 @default.
- W2101472021 cites W1987273027 @default.
- W2101472021 cites W2008936546 @default.
- W2101472021 cites W2009228522 @default.
- W2101472021 cites W2009416280 @default.
- W2101472021 cites W2027918358 @default.
- W2101472021 cites W2037215882 @default.
- W2101472021 cites W2040276985 @default.
- W2101472021 cites W2046465798 @default.
- W2101472021 cites W2063437562 @default.
- W2101472021 cites W2079832232 @default.
- W2101472021 cites W2080901234 @default.
- W2101472021 cites W2125863855 @default.
- W2101472021 cites W2130473466 @default.
- W2101472021 doi "https://doi.org/10.1111/j.1744-313x.1989.tb00483.x" @default.
- W2101472021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2639908" @default.
- W2101472021 hasPublicationYear "1989" @default.
- W2101472021 type Work @default.
- W2101472021 sameAs 2101472021 @default.
- W2101472021 citedByCount "0" @default.
- W2101472021 crossrefType "journal-article" @default.
- W2101472021 hasAuthorship W2101472021A5028224790 @default.
- W2101472021 hasAuthorship W2101472021A5072880997 @default.
- W2101472021 hasAuthorship W2101472021A5087029063 @default.
- W2101472021 hasAuthorship W2101472021A5091556994 @default.
- W2101472021 hasConcept C104317684 @default.
- W2101472021 hasConcept C109825262 @default.
- W2101472021 hasConcept C112212490 @default.
- W2101472021 hasConcept C127716648 @default.
- W2101472021 hasConcept C134305767 @default.
- W2101472021 hasConcept C13514818 @default.
- W2101472021 hasConcept C143065580 @default.
- W2101472021 hasConcept C153911025 @default.
- W2101472021 hasConcept C176944494 @default.
- W2101472021 hasConcept C180754005 @default.
- W2101472021 hasConcept C36823959 @default.
- W2101472021 hasConcept C501734568 @default.
- W2101472021 hasConcept C54355233 @default.
- W2101472021 hasConcept C70883133 @default.
- W2101472021 hasConcept C84597430 @default.
- W2101472021 hasConcept C86803240 @default.
- W2101472021 hasConcept C91779695 @default.
- W2101472021 hasConceptScore W2101472021C104317684 @default.
- W2101472021 hasConceptScore W2101472021C109825262 @default.
- W2101472021 hasConceptScore W2101472021C112212490 @default.
- W2101472021 hasConceptScore W2101472021C127716648 @default.
- W2101472021 hasConceptScore W2101472021C134305767 @default.
- W2101472021 hasConceptScore W2101472021C13514818 @default.
- W2101472021 hasConceptScore W2101472021C143065580 @default.
- W2101472021 hasConceptScore W2101472021C153911025 @default.
- W2101472021 hasConceptScore W2101472021C176944494 @default.
- W2101472021 hasConceptScore W2101472021C180754005 @default.
- W2101472021 hasConceptScore W2101472021C36823959 @default.
- W2101472021 hasConceptScore W2101472021C501734568 @default.
- W2101472021 hasConceptScore W2101472021C54355233 @default.
- W2101472021 hasConceptScore W2101472021C70883133 @default.
- W2101472021 hasConceptScore W2101472021C84597430 @default.
- W2101472021 hasConceptScore W2101472021C86803240 @default.
- W2101472021 hasConceptScore W2101472021C91779695 @default.
- W2101472021 hasIssue "4-5" @default.
- W2101472021 hasLocation W21014720211 @default.
- W2101472021 hasLocation W21014720212 @default.
- W2101472021 hasOpenAccess W2101472021 @default.
- W2101472021 hasPrimaryLocation W21014720211 @default.
- W2101472021 hasRelatedWork W101124211 @default.
- W2101472021 hasRelatedWork W1565901822 @default.
- W2101472021 hasRelatedWork W1575389553 @default.
- W2101472021 hasRelatedWork W1995692004 @default.
- W2101472021 hasRelatedWork W2044701411 @default.
- W2101472021 hasRelatedWork W2057739827 @default.
- W2101472021 hasRelatedWork W2068932327 @default.
- W2101472021 hasRelatedWork W2087473487 @default.
- W2101472021 hasRelatedWork W2140698435 @default.
- W2101472021 hasRelatedWork W2613868166 @default.
- W2101472021 hasVolume "16" @default.
- W2101472021 isParatext "false" @default.
- W2101472021 isRetracted "false" @default.
- W2101472021 magId "2101472021" @default.
- W2101472021 workType "article" @default.