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- W2101474001 abstract "Irritable bowel syndrome (IBS) is a complex disorder that is characterized by abdominal pain and altered bowel habit, and often associates with other gastrointestinal symptoms such as feelings of incomplete bowel movement and abdominal bloating, and extra-intestinal symptoms such as headache, dyspareunia, heartburn, muscle pain, and back pain. It also frequently coexists with conditions that may also involve central sensitization processes, such as fibromyalgia, irritable bladder disorder, and chronic cough. This review examines the evidence to date on gabapentin and pregabalin which may support further and continued research and development of the α(2)δ ligands in disorders characterized by visceral hypersensitivity, such as IBS. The distribution of the α(2)δ subunit of the voltage-gated calcium channel, possible mechanisms of action, pre-clinical data which supports an effect on motor-sensory mechanisms and clinical evidence that points to potential benefits in patients with IBS will be discussed." @default.
- W2101474001 created "2016-06-24" @default.
- W2101474001 creator A5026037485 @default.
- W2101474001 creator A5027281189 @default.
- W2101474001 date "2011-01-01" @default.
- W2101474001 modified "2023-10-13" @default.
- W2101474001 title "Alpha 2 Delta (α2δ) Ligands, Gabapentin and Pregabalin: What is the Evidence for Potential Use of These Ligands in Irritable Bowel Syndrome" @default.
- W2101474001 cites W1603028467 @default.
- W2101474001 cites W1828582259 @default.
- W2101474001 cites W1873448316 @default.
- W2101474001 cites W1902482691 @default.
- W2101474001 cites W1902878432 @default.
- W2101474001 cites W1936115414 @default.
- W2101474001 cites W1965775384 @default.
- W2101474001 cites W1966160259 @default.
- W2101474001 cites W1966720579 @default.
- W2101474001 cites W1967084110 @default.
- W2101474001 cites W1970581037 @default.
- W2101474001 cites W1972403208 @default.
- W2101474001 cites W1975661117 @default.
- W2101474001 cites W1980588138 @default.
- W2101474001 cites W1981639311 @default.
- W2101474001 cites W1985434537 @default.
- W2101474001 cites W1987817571 @default.
- W2101474001 cites W1991013278 @default.
- W2101474001 cites W1994334998 @default.
- W2101474001 cites W1999794762 @default.
- W2101474001 cites W2010829771 @default.
- W2101474001 cites W2014495207 @default.
- W2101474001 cites W2018461659 @default.
- W2101474001 cites W2021532501 @default.
- W2101474001 cites W2023541450 @default.
- W2101474001 cites W2027053525 @default.
- W2101474001 cites W2031004040 @default.
- W2101474001 cites W2036834090 @default.
- W2101474001 cites W2044044822 @default.
- W2101474001 cites W2049171008 @default.
- W2101474001 cites W2053598582 @default.
- W2101474001 cites W2058457307 @default.
- W2101474001 cites W2059864957 @default.
- W2101474001 cites W2060199120 @default.
- W2101474001 cites W2060554922 @default.
- W2101474001 cites W2063170700 @default.
- W2101474001 cites W2063190826 @default.
- W2101474001 cites W2064201279 @default.
- W2101474001 cites W2070284980 @default.
- W2101474001 cites W2070648381 @default.
- W2101474001 cites W2075209865 @default.
- W2101474001 cites W2076464902 @default.
- W2101474001 cites W2076516150 @default.
- W2101474001 cites W2077700052 @default.
- W2101474001 cites W2090477438 @default.
- W2101474001 cites W2099917325 @default.
- W2101474001 cites W2102141504 @default.
- W2101474001 cites W2105445407 @default.
- W2101474001 cites W2109805399 @default.
- W2101474001 cites W2110459138 @default.
- W2101474001 cites W2112286648 @default.
- W2101474001 cites W2113426565 @default.
- W2101474001 cites W2114718043 @default.
- W2101474001 cites W2116511946 @default.
- W2101474001 cites W2117456715 @default.
- W2101474001 cites W2118842320 @default.
- W2101474001 cites W2122262547 @default.
- W2101474001 cites W2122304769 @default.
- W2101474001 cites W2126452889 @default.
- W2101474001 cites W2136298776 @default.
- W2101474001 cites W2138177961 @default.
- W2101474001 cites W2143094870 @default.
- W2101474001 cites W2145558296 @default.
- W2101474001 cites W2147148035 @default.
- W2101474001 cites W2150287168 @default.
- W2101474001 cites W2150860854 @default.
- W2101474001 cites W2151454520 @default.
- W2101474001 cites W2152940786 @default.
- W2101474001 cites W2157003537 @default.
- W2101474001 cites W2157275283 @default.
- W2101474001 cites W2159332152 @default.
- W2101474001 cites W2168058358 @default.
- W2101474001 cites W2205531850 @default.
- W2101474001 cites W2261044925 @default.
- W2101474001 cites W2346657510 @default.
- W2101474001 cites W2411442671 @default.
- W2101474001 cites W2619099808 @default.
- W2101474001 cites W85539995 @default.
- W2101474001 doi "https://doi.org/10.3389/fphar.2011.00028" @default.
- W2101474001 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3114047" @default.
- W2101474001 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21713059" @default.
- W2101474001 hasPublicationYear "2011" @default.
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