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- W2101488052 endingPage "9284" @default.
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- W2101488052 abstract "ABSTRACT The ERV3 locus at chromosome 7q11 is a much studied human endogenous retroviral (HERV) sequence, owing to an env open reading frame (ORF) and placental RNA and protein expression. An analysis of the human genome demonstrated that ERV3 is one of a group of 41 highly related elements (ERV3-like HERVs) which use proline, isoleucine, or arginine tRNA in their primer binding sites. In addition to elements closely related to ERV3, the group included the previously known retinoic acid-inducible element, RRHERVI, also referred to as HERV15, but was separate from the related HERV-E elements. The ERV3-like elements are defective. The only element with an ORF among gag , pro , pol , and env genes was the env ORF of the original ERV3 locus. A search in dbEST revealed ERV3 RNA expression in placenta, skin, carcinoid tumor, and adrenal glands. Expression was also studied with newly developed real-time quantitative PCRs (QPCR) of ERV3 and HERV-E(4-1) env sequences. Results from a novel histone 3.3 RNA QPCR result served as the expression control. QPCR results for ERV3 were compatible with previously published results, with a stronger expression in adrenal gland and placenta than in 15 other human tissues. The expression of the envelope ( env ) of ERV3 at chromosome 7q11 was also studied by using stringent in situ hybridization. Expression was found in corpus luteum, testis, adrenal gland, Hassal's bodies in thymus, brown fat, pituitary gland, and epithelium of the lung. We conclude that ERV3 env is most strongly expressed in adrenal and sebaceous glands as well as in placenta." @default.
- W2101488052 created "2016-06-24" @default.
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- W2101488052 creator A5047314166 @default.
- W2101488052 creator A5050629872 @default.
- W2101488052 date "2005-07-01" @default.
- W2101488052 modified "2023-10-18" @default.
- W2101488052 title "ERV3 and Related Sequences in Humans: Structure and RNA Expression" @default.
- W2101488052 cites W129915083 @default.
- W2101488052 cites W1491910236 @default.
- W2101488052 cites W1523313546 @default.
- W2101488052 cites W1568321676 @default.
- W2101488052 cites W1577577364 @default.
- W2101488052 cites W1592445034 @default.
- W2101488052 cites W160780385 @default.
- W2101488052 cites W1894623846 @default.
- W2101488052 cites W1911295802 @default.
- W2101488052 cites W1947893030 @default.
- W2101488052 cites W1956732739 @default.
- W2101488052 cites W1963902578 @default.
- W2101488052 cites W1966585515 @default.
- W2101488052 cites W1970222862 @default.
- W2101488052 cites W1974644460 @default.
- W2101488052 cites W1979107629 @default.
- W2101488052 cites W1979204390 @default.
- W2101488052 cites W1985556220 @default.
- W2101488052 cites W1988095531 @default.
- W2101488052 cites W1993862102 @default.
- W2101488052 cites W1997563286 @default.
- W2101488052 cites W1997688114 @default.
- W2101488052 cites W1997960846 @default.
- W2101488052 cites W1998066154 @default.
- W2101488052 cites W2002146446 @default.
- W2101488052 cites W2007685547 @default.
- W2101488052 cites W2010885715 @default.
- W2101488052 cites W2013246689 @default.
- W2101488052 cites W2017749542 @default.
- W2101488052 cites W2019039822 @default.
- W2101488052 cites W2025226074 @default.
- W2101488052 cites W2026397666 @default.
- W2101488052 cites W2026757160 @default.
- W2101488052 cites W2028370765 @default.
- W2101488052 cites W2030508781 @default.
- W2101488052 cites W2031443751 @default.
- W2101488052 cites W2031731244 @default.
- W2101488052 cites W2033035694 @default.
- W2101488052 cites W2034590239 @default.
- W2101488052 cites W2036721131 @default.
- W2101488052 cites W2038815954 @default.
- W2101488052 cites W2039469440 @default.
- W2101488052 cites W2041383836 @default.
- W2101488052 cites W2044545721 @default.
- W2101488052 cites W2044648165 @default.
- W2101488052 cites W2053700542 @default.
- W2101488052 cites W2055043387 @default.
- W2101488052 cites W2055954681 @default.
- W2101488052 cites W2056329906 @default.
- W2101488052 cites W2064541625 @default.
- W2101488052 cites W2068157014 @default.
- W2101488052 cites W2070068513 @default.
- W2101488052 cites W2079159166 @default.
- W2101488052 cites W2079979541 @default.
- W2101488052 cites W2101899458 @default.
- W2101488052 cites W2106739119 @default.
- W2101488052 cites W2106882534 @default.
- W2101488052 cites W2108447651 @default.
- W2101488052 cites W2110185450 @default.
- W2101488052 cites W2112203237 @default.
- W2101488052 cites W2119322510 @default.
- W2101488052 cites W2142204199 @default.
- W2101488052 cites W2145651349 @default.
- W2101488052 cites W2146527174 @default.
- W2101488052 cites W2150785328 @default.
- W2101488052 cites W2154121432 @default.
- W2101488052 cites W2155428691 @default.
- W2101488052 cites W2155710269 @default.
- W2101488052 cites W2157103983 @default.
- W2101488052 cites W2158361859 @default.
- W2101488052 cites W2161441850 @default.
- W2101488052 cites W2165382801 @default.
- W2101488052 cites W2167184077 @default.
- W2101488052 cites W2167804386 @default.
- W2101488052 cites W2170167244 @default.
- W2101488052 cites W2172039585 @default.
- W2101488052 cites W2173570428 @default.
- W2101488052 cites W2211047102 @default.
- W2101488052 cites W2257033327 @default.
- W2101488052 cites W2413766269 @default.
- W2101488052 cites W4238047074 @default.
- W2101488052 cites W2400362350 @default.
- W2101488052 doi "https://doi.org/10.1128/jvi.79.14.9270-9284.2005" @default.
- W2101488052 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1168766" @default.
- W2101488052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15994821" @default.
- W2101488052 hasPublicationYear "2005" @default.
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