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- W2101508740 abstract "C57BL mice were depleted of macrophages by an intravenous injection of liposome-encapsulated dichloromethylene diphosphonate (DCMDP), and control mice were uninjected or injected with empty liposomes. One day after injection, a proportion of the DCMDP-treated and control mice was continuously exposed to ethanol vapor for 4 days. Albumin fractions were separated from the sera of both ethanol-unexposed and ethanol-exposed animals and tested for cytotoxicity against a monolayer of A9 cells using two indicators of cytotoxicity: detachment of adherent cells and a decrease in the ability of cells to reduce tetrazolium. The results show that, in mice exposed to ethanol, macrophages are a major source of the acetaldehyde in circulating cytotoxic acetaldehyde-albumin complexes and presumably also of free acetaldehyde." @default.
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- W2101508740 date "1994-12-01" @default.
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- W2101508740 title "Macrophages Are a Major Source of Acetaldehyde in Circulating Acetaldehyde-Albumin Complexes Formed after Exposure of Mice to Ethanol" @default.
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- W2101508740 doi "https://doi.org/10.1111/j.1530-0277.1994.tb01451.x" @default.
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