FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101509369> ?p ?o ?g. }

• W2101509369 endingPage "607" @default.
• W2101509369 startingPage "600" @default.
• W2101509369 abstract "AimTo investigate the effects of angiotensin-converting enzyme inhibitor (cilazapril) and angiotensin II type I receptor antagonist (losartan) on tubular and interstitial cell apoptosis and caspase-3 activity in rats with obstructive nephropathy after unilateral ureteral obstruction.MethodsRats with unilateral obstructive nephropathy and sham-operated rats were treated with cilazapril, losartan, or the vehicle (water). Tubular and interstitial cell apoptosis was detected morphologically on hematoxylin and eosin-stained renal specimens and by the terminal deoxynucleotidyl transferase-mediated nick end-labeling. Caspase-3 activity in whole-kidney tissue homogenates was measured colorimetrically.ResultsAfter unilateral ureter ligation, there was a significant increase in the number of apoptotic tubular and interstitial cells in the obstructed kidney (13.17 ± 8.73 vs 3.00 ± 4.53 cells per high power field; P = 0.049 and 6.33 ± 3.27 vs 2.00 ± 2.35 cells per high power field; P = 0.036 vs sham-operated rats, 10 days after ligation). In rats with unilateral obstructive nephropathy, neither cilazapril nor losartan had an effect on tubular cell apoptosis. However, cilazapril caused a significant increase in the number of renal apoptotic interstitial cells (7.00 ± 9.74 vs 0.8 ± 1.41 cells per high power field, P = 0.019). Caspase-3 activity was not significantly different in rats with unilateral obstructive nephropathy than in sham-operated rats.ConclusionRats with unilateral obstructive nephropathy had increased apoptosis of tubular and interstitial cells in comparison with sham-operated rats. Neither cilazapril nor losartan had an effect on tubular cell apoptosis, and cilazapril even increased interstitial cell apoptosis." @default.
• W2101509369 created "2016-06-24" @default.
• W2101509369 creator A5007500559 @default.
• W2101509369 creator A5069301981 @default.
• W2101509369 creator A5091229136 @default.
• W2101509369 date "2008-10-01" @default.
• W2101509369 modified "2023-10-16" @default.
• W2101509369 title "Effect of Unilateral Ureteral Obstruction and Anti-angiotensin II Treatment on Renal Tubule and Interstitial Cell Apoptosis in Rats" @default.
• W2101509369 cites W1544498305 @default.
• W2101509369 cites W1942214720 @default.
• W2101509369 cites W1968429651 @default.
• W2101509369 cites W1973284699 @default.
• W2101509369 cites W1981147213 @default.
• W2101509369 cites W1994469526 @default.
• W2101509369 cites W2001259350 @default.
• W2101509369 cites W2001931269 @default.
• W2101509369 cites W2004612291 @default.
• W2101509369 cites W2012142430 @default.
• W2101509369 cites W2013583594 @default.
• W2101509369 cites W2016254825 @default.
• W2101509369 cites W2021436849 @default.
• W2101509369 cites W2026629747 @default.
• W2101509369 cites W2040483294 @default.
• W2101509369 cites W2046259472 @default.
• W2101509369 cites W2046401185 @default.
• W2101509369 cites W2048088842 @default.
• W2101509369 cites W2056657456 @default.
• W2101509369 cites W2059788781 @default.
• W2101509369 cites W2060545985 @default.
• W2101509369 cites W2070674743 @default.
• W2101509369 cites W2072874642 @default.
• W2101509369 cites W2074563181 @default.
• W2101509369 cites W2088238268 @default.
• W2101509369 cites W2118755851 @default.
• W2101509369 cites W2123954705 @default.
• W2101509369 cites W2125589586 @default.
• W2101509369 cites W2131757138 @default.
• W2101509369 cites W2137169969 @default.
• W2101509369 cites W2151501496 @default.
• W2101509369 cites W2168720263 @default.
• W2101509369 cites W2411761368 @default.
• W2101509369 doi "https://doi.org/10.3325/cmj.2008.5.600" @default.
• W2101509369 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2582352" @default.
• W2101509369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18925693" @default.
• W2101509369 hasPublicationYear "2008" @default.
• W2101509369 type Work @default.
• W2101509369 sameAs 2101509369 @default.
• W2101509369 citedByCount "12" @default.
• W2101509369 countsByYear W21015093692013 @default.
• W2101509369 countsByYear W21015093692014 @default.
• W2101509369 countsByYear W21015093692017 @default.
• W2101509369 countsByYear W21015093692018 @default.
• W2101509369 countsByYear W21015093692019 @default.
• W2101509369 countsByYear W21015093692021 @default.
• W2101509369 crossrefType "journal-article" @default.
• W2101509369 hasAuthorship W2101509369A5007500559 @default.
• W2101509369 hasAuthorship W2101509369A5069301981 @default.
• W2101509369 hasAuthorship W2101509369A5091229136 @default.
• W2101509369 hasBestOaLocation W21015093691 @default.
• W2101509369 hasConcept C126322002 @default.
• W2101509369 hasConcept C134018914 @default.
• W2101509369 hasConcept C154113507 @default.
• W2101509369 hasConcept C170493617 @default.
• W2101509369 hasConcept C185592680 @default.
• W2101509369 hasConcept C190283241 @default.
• W2101509369 hasConcept C196795494 @default.
• W2101509369 hasConcept C204232928 @default.
• W2101509369 hasConcept C27016395 @default.
• W2101509369 hasConcept C2777534427 @default.
• W2101509369 hasConcept C2779611605 @default.
• W2101509369 hasConcept C2780091579 @default.
• W2101509369 hasConcept C2780288358 @default.
• W2101509369 hasConcept C2781184683 @default.
• W2101509369 hasConcept C2781352967 @default.
• W2101509369 hasConcept C2908929049 @default.
• W2101509369 hasConcept C55493867 @default.
• W2101509369 hasConcept C555293320 @default.
• W2101509369 hasConcept C71924100 @default.
• W2101509369 hasConcept C84393581 @default.
• W2101509369 hasConceptScore W2101509369C126322002 @default.
• W2101509369 hasConceptScore W2101509369C134018914 @default.
• W2101509369 hasConceptScore W2101509369C154113507 @default.
• W2101509369 hasConceptScore W2101509369C170493617 @default.
• W2101509369 hasConceptScore W2101509369C185592680 @default.
• W2101509369 hasConceptScore W2101509369C190283241 @default.
• W2101509369 hasConceptScore W2101509369C196795494 @default.
• W2101509369 hasConceptScore W2101509369C204232928 @default.
• W2101509369 hasConceptScore W2101509369C27016395 @default.
• W2101509369 hasConceptScore W2101509369C2777534427 @default.
• W2101509369 hasConceptScore W2101509369C2779611605 @default.
• W2101509369 hasConceptScore W2101509369C2780091579 @default.
• W2101509369 hasConceptScore W2101509369C2780288358 @default.
• W2101509369 hasConceptScore W2101509369C2781184683 @default.
• W2101509369 hasConceptScore W2101509369C2781352967 @default.
• W2101509369 hasConceptScore W2101509369C2908929049 @default.
• W2101509369 hasConceptScore W2101509369C55493867 @default.
• W2101509369 hasConceptScore W2101509369C555293320 @default.
• W2101509369 hasConceptScore W2101509369C71924100 @default.

• next