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• W2101536034 abstract "Irene Tracey and Catherine Bushnell 19 Tracey I. Bushnell M.C. How neuroimaging studies have challenged us to rethink: Is chronic pain a disease?. J Pain. 2009; 10: 1113-1120 Abstract Full Text Full Text PDF PubMed Scopus (312) Google Scholar have made a substantial contribution to the ever growing and expanding literature supporting the concept of “pain” as a “disease entity” versus a syndrome or symptom. The neuroimaging data are all but overwhelming. Their call for a “paradigm shift” echoes that of many others including Cousins, 4 Cousins M.J. A challenge for the next decade: The effective presentation of persistent pain as a disease entity. in: Mahajan G. Fishman S. Plenary Proceedings of the 24th Annual Meeting. American Academy of Pain Medicine, Glenview, IL2008: 1-17 Google Scholar , 15 Siddall P.J. Cousins M.J. Persistent pain as a disease entity: implications for clinical management. Anesth Analg. 2004; 99: 510-520 Crossref PubMed Scopus (250) Google Scholar Loeser and Melzack, 7 Loeser J.D. Melzack R. Pain: An overview. The Lancet. 1999; 53: 1607-1609 Abstract Full Text Full Text PDF Scopus (397) Google Scholar Basbaum and Julius, 2 Basbaum A. Julis D. Toward better pain control. Sci Am. 2006; 294: 61-67 Crossref Scopus (18) Google Scholar Niv and Devor, 13 Niv D. Devor M. Chronic pain as a disease in its own right. Pain Practice. 2004; 4: 179-181 Crossref PubMed Google Scholar and Ballantyne. 1 Ballantyne J.C. Opioids for chronic nonterminal pain. South Med J. 2006; 99: 1245-1255 Crossref PubMed Scopus (47) Google Scholar How Neuroimaging Studies Have Challenged Us to Rethink: Is Chronic Pain a Disease?The Journal of PainVol. 10Issue 11PreviewIn this review, we present data from functional, structural, and molecular imaging studies in patients and animals supporting the notion that it might be time to reconsider chronic pain as a disease. Across a range of chronic pain conditions, similar observations have been made regarding changes in structure and function within the brains of patients. We discuss these observations within the framework of the current definition of a disease. Full-Text PDF" @default.
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• W2101536034 title "How Neuroimaging Studies Have Challenged Us to Rethink: Is Chronic Pain a Disease?" @default.
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• W2101536034 doi "https://doi.org/10.1016/j.jpain.2010.01.004" @default.
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