FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101615512> ?p ?o ?g. }

• W2101615512 endingPage "1920" @default.
• W2101615512 startingPage "1918" @default.
• W2101615512 abstract "NF kappa B (NF-kappaB) is a ubiquitous transcription factor activated by various stimuli implicated in heart failure progression including reactive oxygen species (ROS), hypoxia, and inflammatory cytokines. Although NF-kappaB is involved in ischemic preconditioning, unstable angina pectoris, and atherogenesis, its role in heart failure has not been determined. Therefore, we investigated left ventricular remodeling in mice with a targeted deletion of the NF-kappaB subunit p50/NF-kappaB1 after myocardial infarction.p50 knockout (KO) and wild-type (WT) animals underwent coronary artery ligation. Transthoracic echocardiography was performed at days 0, 21, and 56 at midpapillary levels. Early mortality was significantly lower in KO than in WT animals. Moreover, p50 KOs exhibited significantly reduced ventricular dilatation over 8 wk compared to WT controls (end-systolic diameters by transthoracic echocardiography, WT vs. KO, 0.55+/-0.04 vs. 0.34+/-0.03 cm) and preserved left ventricular contractility. Collagen content and matrixmetalloproteinase (MMP) -9 expression were significantly lower in KO mice after myocardial infarction and may account for improved left ventricular remodeling.Absence of the NF-kappaB subunit p50 improves early survival and reduces left ventricular dilatation after myocardial infarction. NF-kappaB might therefore be an attractive target to treat heart failure." @default.
• W2101615512 created "2016-06-24" @default.
• W2101615512 creator A5010484968 @default.
• W2101615512 creator A5012214727 @default.
• W2101615512 creator A5016118935 @default.
• W2101615512 creator A5053785057 @default.
• W2101615512 creator A5062186674 @default.
• W2101615512 creator A5071474093 @default.
• W2101615512 creator A5071736019 @default.
• W2101615512 creator A5088775153 @default.
• W2101615512 date "2006-07-12" @default.
• W2101615512 modified "2023-10-14" @default.
• W2101615512 title "Absence of NF‐κB subunit p50 improves heart failure after myocardial infarction" @default.
• W2101615512 cites W1968099944 @default.
• W2101615512 cites W1988036810 @default.
• W2101615512 cites W2002958873 @default.
• W2101615512 cites W2022066415 @default.
• W2101615512 cites W2024470090 @default.
• W2101615512 cites W2025420553 @default.
• W2101615512 cites W2027835440 @default.
• W2101615512 cites W2035616122 @default.
• W2101615512 cites W2036180183 @default.
• W2101615512 cites W2043359085 @default.
• W2101615512 cites W2043400545 @default.
• W2101615512 cites W2073808890 @default.
• W2101615512 cites W2074994532 @default.
• W2101615512 cites W2075113278 @default.
• W2101615512 cites W2078171723 @default.
• W2101615512 cites W2087549039 @default.
• W2101615512 cites W2087750804 @default.
• W2101615512 cites W2098921416 @default.
• W2101615512 cites W2108103540 @default.
• W2101615512 cites W2124894661 @default.
• W2101615512 cites W2159092701 @default.
• W2101615512 cites W2166781237 @default.
• W2101615512 doi "https://doi.org/10.1096/fj.05-5133fje" @default.
• W2101615512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16837548" @default.
• W2101615512 hasPublicationYear "2006" @default.
• W2101615512 type Work @default.
• W2101615512 sameAs 2101615512 @default.
• W2101615512 citedByCount "129" @default.
• W2101615512 countsByYear W21016155122012 @default.
• W2101615512 countsByYear W21016155122013 @default.
• W2101615512 countsByYear W21016155122014 @default.
• W2101615512 countsByYear W21016155122015 @default.
• W2101615512 countsByYear W21016155122016 @default.
• W2101615512 countsByYear W21016155122017 @default.
• W2101615512 countsByYear W21016155122018 @default.
• W2101615512 countsByYear W21016155122019 @default.
• W2101615512 countsByYear W21016155122020 @default.
• W2101615512 countsByYear W21016155122021 @default.
• W2101615512 countsByYear W21016155122022 @default.
• W2101615512 countsByYear W21016155122023 @default.
• W2101615512 crossrefType "journal-article" @default.
• W2101615512 hasAuthorship W2101615512A5010484968 @default.
• W2101615512 hasAuthorship W2101615512A5012214727 @default.
• W2101615512 hasAuthorship W2101615512A5016118935 @default.
• W2101615512 hasAuthorship W2101615512A5053785057 @default.
• W2101615512 hasAuthorship W2101615512A5062186674 @default.
• W2101615512 hasAuthorship W2101615512A5071474093 @default.
• W2101615512 hasAuthorship W2101615512A5071736019 @default.
• W2101615512 hasAuthorship W2101615512A5088775153 @default.
• W2101615512 hasConcept C126322002 @default.
• W2101615512 hasConcept C164705383 @default.
• W2101615512 hasConcept C178790620 @default.
• W2101615512 hasConcept C179437574 @default.
• W2101615512 hasConcept C185592680 @default.
• W2101615512 hasConcept C2777798775 @default.
• W2101615512 hasConcept C2778198053 @default.
• W2101615512 hasConcept C2779537366 @default.
• W2101615512 hasConcept C39133596 @default.
• W2101615512 hasConcept C500558357 @default.
• W2101615512 hasConcept C540031477 @default.
• W2101615512 hasConcept C71924100 @default.
• W2101615512 hasConcept C7836513 @default.
• W2101615512 hasConceptScore W2101615512C126322002 @default.
• W2101615512 hasConceptScore W2101615512C164705383 @default.
• W2101615512 hasConceptScore W2101615512C178790620 @default.
• W2101615512 hasConceptScore W2101615512C179437574 @default.
• W2101615512 hasConceptScore W2101615512C185592680 @default.
• W2101615512 hasConceptScore W2101615512C2777798775 @default.
• W2101615512 hasConceptScore W2101615512C2778198053 @default.
• W2101615512 hasConceptScore W2101615512C2779537366 @default.
• W2101615512 hasConceptScore W2101615512C39133596 @default.
• W2101615512 hasConceptScore W2101615512C500558357 @default.
• W2101615512 hasConceptScore W2101615512C540031477 @default.
• W2101615512 hasConceptScore W2101615512C71924100 @default.
• W2101615512 hasConceptScore W2101615512C7836513 @default.
• W2101615512 hasIssue "11" @default.
• W2101615512 hasLocation W21016155121 @default.
• W2101615512 hasLocation W21016155122 @default.
• W2101615512 hasOpenAccess W2101615512 @default.
• W2101615512 hasPrimaryLocation W21016155121 @default.
• W2101615512 hasRelatedWork W1864361583 @default.
• W2101615512 hasRelatedWork W1987449336 @default.
• W2101615512 hasRelatedWork W2068259322 @default.
• W2101615512 hasRelatedWork W2075010150 @default.
• W2101615512 hasRelatedWork W2358303362 @default.

• next