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• W2101697203 abstract "This paper reviews leech development up to the 12-cell embryo. Oogenesis proceeds by a system of nurse cells that contribute to oocyte growth via continuous cytoplasmic connections. Development begins when fertilized eggs are deposited: formation of the polar bodies, and centration of the male and female pro-nuclei is accompanied by cytoskeletal contractions, and formation of teloplasm (yolk-free cytoplasm). The first cleavages are asymmetric: cell D', the largest macromere in the eight-cell embryo, contains most of the teloplasm. At fourth cleavage D' divides equally; its animal and vegetal daughters are precursors of segmental ectoderm and mesoderm, respectively. Teloplasm is a determinant of the D' cell fate. The expression pattern of Hro-nos, a leech homolog to the Drosophila gene nanos, suggests that it may be a determinant associated with the animal cortex and inducing the ectodermal fate in the animal daughter cell of the D' macromere." @default.
• W2101697203 created "2016-06-24" @default.
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• W2101697203 date "1997-08-01" @default.
• W2101697203 modified "2023-10-15" @default.
• W2101697203 title "Early events leading to fate decisions during leech embryogenesis" @default.
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• W2101697203 doi "https://doi.org/10.1006/scdb.1997.0159" @default.
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