FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101699778> ?p ?o ?g. }

• W2101699778 endingPage "3540" @default.
• W2101699778 startingPage "3533" @default.
• W2101699778 abstract "Saccharomyces cerevisiae glutamate synthase (GOGAT) is an oligomeric enzyme composed of three 199-kDa identical subunits encoded by GLT1. In this work, we analyzed GLT1 transcriptional regulation. GLT1-lacZ fusions were prepared and GLT1 expression was determined in a GDH1 wild-type strain and in a gdh1 mutant derivative grown in the presence of various nitrogen sources. Null mutants impaired in GCN4, GLN3, GAT1/NIL1, or UGA43/DAL80 were transformed with a GLT1-lacZ fusion to determine whether the above-mentioned transcriptional factors had a role in GLT1 expression. A collection of increasingly larger 5' deletion derivatives of the GLT1 promoter was constructed to identify DNA sequences that could be involved in GLT1 transcriptional regulation. The effect of the lack of GCN4, GLN3, or GAT1/NIL1 was also tested in the pertinent 5' deletion derivatives. Our results indicate that (i) GLT1 expression is negatively modulated by glutamate-mediated repression and positively regulated by Gln3p- and Gcn4p-dependent transcriptional activation; (ii) two cis-acting elements, a CGGN15CCG palindrome and an imperfect poly(dA-dT), are present and could play a role in GLT1 transcriptional activation; and (iii) GLT1 expression is moderately regulated by GCN4 under amino acid deprivation. Our results suggest that in a wild-type strain grown on ammonium, GOGAT constitutes an ancillary pathway for glutamate biosynthesis." @default.
• W2101699778 created "2016-06-24" @default.
• W2101699778 creator A5019946331 @default.
• W2101699778 creator A5035369119 @default.
• W2101699778 creator A5036009946 @default.
• W2101699778 creator A5042704600 @default.
• W2101699778 creator A5060482696 @default.
• W2101699778 date "1998-07-15" @default.
• W2101699778 modified "2023-10-05" @default.
• W2101699778 title "Regulation of Expression of <i>GLT1</i> , the Gene Encoding Glutamate Synthase in <i>Saccharomyces cerevisiae</i>" @default.
• W2101699778 cites W11367174 @default.
• W2101699778 cites W1528511552 @default.
• W2101699778 cites W1564217760 @default.
• W2101699778 cites W1564269649 @default.
• W2101699778 cites W1571839798 @default.
• W2101699778 cites W1637451669 @default.
• W2101699778 cites W1653847549 @default.
• W2101699778 cites W1759206404 @default.
• W2101699778 cites W1775749144 @default.
• W2101699778 cites W1824434532 @default.
• W2101699778 cites W1876359300 @default.
• W2101699778 cites W1935948820 @default.
• W2101699778 cites W1955905392 @default.
• W2101699778 cites W1970921900 @default.
• W2101699778 cites W1973782344 @default.
• W2101699778 cites W2001664444 @default.
• W2101699778 cites W2015752128 @default.
• W2101699778 cites W2015934026 @default.
• W2101699778 cites W2019271341 @default.
• W2101699778 cites W2023756920 @default.
• W2101699778 cites W2037320558 @default.
• W2101699778 cites W2038656065 @default.
• W2101699778 cites W2041086696 @default.
• W2101699778 cites W2053000428 @default.
• W2101699778 cites W2068268311 @default.
• W2101699778 cites W2078427108 @default.
• W2101699778 cites W2080139629 @default.
• W2101699778 cites W2092745646 @default.
• W2101699778 cites W2096626341 @default.
• W2101699778 cites W2097908805 @default.
• W2101699778 cites W2109788296 @default.
• W2101699778 cites W2112139159 @default.
• W2101699778 cites W2133875593 @default.
• W2101699778 cites W2135174208 @default.
• W2101699778 cites W2137994430 @default.
• W2101699778 cites W2139072451 @default.
• W2101699778 cites W2140663847 @default.
• W2101699778 cites W2161817279 @default.
• W2101699778 cites W2168134766 @default.
• W2101699778 cites W2169387898 @default.
• W2101699778 cites W2171618839 @default.
• W2101699778 cites W2214383802 @default.
• W2101699778 cites W2224465247 @default.
• W2101699778 cites W2466932726 @default.
• W2101699778 cites W4233137426 @default.
• W2101699778 cites W4252498477 @default.
• W2101699778 cites W4255797102 @default.
• W2101699778 cites W54748642 @default.
• W2101699778 doi "https://doi.org/10.1128/jb.180.14.3533-3540.1998" @default.
• W2101699778 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/107319" @default.
• W2101699778 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9657994" @default.
• W2101699778 hasPublicationYear "1998" @default.
• W2101699778 type Work @default.
• W2101699778 sameAs 2101699778 @default.
• W2101699778 citedByCount "52" @default.
• W2101699778 countsByYear W21016997782012 @default.
• W2101699778 countsByYear W21016997782013 @default.
• W2101699778 countsByYear W21016997782014 @default.
• W2101699778 countsByYear W21016997782016 @default.
• W2101699778 countsByYear W21016997782017 @default.
• W2101699778 countsByYear W21016997782019 @default.
• W2101699778 countsByYear W21016997782020 @default.
• W2101699778 countsByYear W21016997782022 @default.
• W2101699778 countsByYear W21016997782023 @default.
• W2101699778 crossrefType "journal-article" @default.
• W2101699778 hasAuthorship W2101699778A5019946331 @default.
• W2101699778 hasAuthorship W2101699778A5035369119 @default.
• W2101699778 hasAuthorship W2101699778A5036009946 @default.
• W2101699778 hasAuthorship W2101699778A5042704600 @default.
• W2101699778 hasAuthorship W2101699778A5060482696 @default.
• W2101699778 hasBestOaLocation W21016997781 @default.
• W2101699778 hasConcept C104317684 @default.
• W2101699778 hasConcept C112243037 @default.
• W2101699778 hasConcept C143065580 @default.
• W2101699778 hasConcept C153911025 @default.
• W2101699778 hasConcept C191771488 @default.
• W2101699778 hasConcept C2777576037 @default.
• W2101699778 hasConcept C2779289688 @default.
• W2101699778 hasConcept C2779349466 @default.
• W2101699778 hasConcept C515207424 @default.
• W2101699778 hasConcept C54355233 @default.
• W2101699778 hasConcept C55493867 @default.
• W2101699778 hasConcept C86803240 @default.
• W2101699778 hasConceptScore W2101699778C104317684 @default.
• W2101699778 hasConceptScore W2101699778C112243037 @default.
• W2101699778 hasConceptScore W2101699778C143065580 @default.
• W2101699778 hasConceptScore W2101699778C153911025 @default.
• W2101699778 hasConceptScore W2101699778C191771488 @default.

• next