Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101706072> ?p ?o ?g. }
- W2101706072 endingPage "687" @default.
- W2101706072 startingPage "681" @default.
- W2101706072 abstract "The aim of the present study was to detect antigenic proteins that react specifically with cerebrospinal fluid (CSF)-IgG from oligoclonal IgG bands (OB)-positive multiple sclerosis (MS) patients. To identify such antigenic proteins, we developed a rat brain proteome map using 2-DE and applied it to the immunoscreening of brain proteins that react with CSF-IgG but not with serum-IgG in OB-positive MS patients. After sequential MALDI-TOF mass spectrometry, eight proteins [two neuronal proteins (tubulin β-2 and γ enolase-2), HSP-1, Tpi-1 protein and cellular enzymes (creatine kinase, phosphopyruvate hydratase, triosephosphate isomerase and phosphoglycerate kinase-1)] were identified as candidate antigens in seven MS patients. Reactivity to tubulin was seen in Western blotting in four patients, and CSF-specific anti-tubulin IgG was detected in one patient. In addition, CSF-specific anti-gamma enolase IgG was found in another patient. These findings suggest that intrathecal immune responses may occur against a broad range of proteins in MS." @default.
- W2101706072 created "2016-06-24" @default.
- W2101706072 creator A5006528411 @default.
- W2101706072 creator A5010508025 @default.
- W2101706072 creator A5050470835 @default.
- W2101706072 creator A5068037677 @default.
- W2101706072 creator A5077929630 @default.
- W2101706072 date "2007-07-01" @default.
- W2101706072 modified "2023-10-18" @default.
- W2101706072 title "Candidate antigens specifically detected by cerebrospinal fluid-IgG in oligoclonal IgG bands-positive multiple sclerosis patients" @default.
- W2101706072 cites W1575041997 @default.
- W2101706072 cites W1964607444 @default.
- W2101706072 cites W1970046036 @default.
- W2101706072 cites W1971515423 @default.
- W2101706072 cites W1972348353 @default.
- W2101706072 cites W1977980254 @default.
- W2101706072 cites W1980695358 @default.
- W2101706072 cites W1982582935 @default.
- W2101706072 cites W1990442094 @default.
- W2101706072 cites W2008749100 @default.
- W2101706072 cites W2014287294 @default.
- W2101706072 cites W2027483802 @default.
- W2101706072 cites W2040337484 @default.
- W2101706072 cites W2045617789 @default.
- W2101706072 cites W2049741849 @default.
- W2101706072 cites W2049878941 @default.
- W2101706072 cites W2050522424 @default.
- W2101706072 cites W2060042291 @default.
- W2101706072 cites W2062584366 @default.
- W2101706072 cites W2065171839 @default.
- W2101706072 cites W2072212529 @default.
- W2101706072 cites W2093471482 @default.
- W2101706072 cites W2096220364 @default.
- W2101706072 cites W2105490558 @default.
- W2101706072 cites W2122077291 @default.
- W2101706072 cites W2147126479 @default.
- W2101706072 cites W2157497376 @default.
- W2101706072 cites W2165629556 @default.
- W2101706072 cites W2168726651 @default.
- W2101706072 cites W2172052207 @default.
- W2101706072 cites W4296926797 @default.
- W2101706072 cites W2002745802 @default.
- W2101706072 doi "https://doi.org/10.1002/prca.200700182" @default.
- W2101706072 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21136723" @default.
- W2101706072 hasPublicationYear "2007" @default.
- W2101706072 type Work @default.
- W2101706072 sameAs 2101706072 @default.
- W2101706072 citedByCount "2" @default.
- W2101706072 crossrefType "journal-article" @default.
- W2101706072 hasAuthorship W2101706072A5006528411 @default.
- W2101706072 hasAuthorship W2101706072A5010508025 @default.
- W2101706072 hasAuthorship W2101706072A5050470835 @default.
- W2101706072 hasAuthorship W2101706072A5068037677 @default.
- W2101706072 hasAuthorship W2101706072A5077929630 @default.
- W2101706072 hasConcept C104397665 @default.
- W2101706072 hasConcept C142724271 @default.
- W2101706072 hasConcept C147483822 @default.
- W2101706072 hasConcept C153911025 @default.
- W2101706072 hasConcept C159654299 @default.
- W2101706072 hasConcept C185592680 @default.
- W2101706072 hasConcept C188618488 @default.
- W2101706072 hasConcept C203014093 @default.
- W2101706072 hasConcept C204232928 @default.
- W2101706072 hasConcept C2779651940 @default.
- W2101706072 hasConcept C2780640218 @default.
- W2101706072 hasConcept C2780898057 @default.
- W2101706072 hasConcept C55493867 @default.
- W2101706072 hasConcept C71924100 @default.
- W2101706072 hasConcept C86803240 @default.
- W2101706072 hasConceptScore W2101706072C104397665 @default.
- W2101706072 hasConceptScore W2101706072C142724271 @default.
- W2101706072 hasConceptScore W2101706072C147483822 @default.
- W2101706072 hasConceptScore W2101706072C153911025 @default.
- W2101706072 hasConceptScore W2101706072C159654299 @default.
- W2101706072 hasConceptScore W2101706072C185592680 @default.
- W2101706072 hasConceptScore W2101706072C188618488 @default.
- W2101706072 hasConceptScore W2101706072C203014093 @default.
- W2101706072 hasConceptScore W2101706072C204232928 @default.
- W2101706072 hasConceptScore W2101706072C2779651940 @default.
- W2101706072 hasConceptScore W2101706072C2780640218 @default.
- W2101706072 hasConceptScore W2101706072C2780898057 @default.
- W2101706072 hasConceptScore W2101706072C55493867 @default.
- W2101706072 hasConceptScore W2101706072C71924100 @default.
- W2101706072 hasConceptScore W2101706072C86803240 @default.
- W2101706072 hasIssue "7" @default.
- W2101706072 hasLocation W21017060721 @default.
- W2101706072 hasLocation W21017060722 @default.
- W2101706072 hasOpenAccess W2101706072 @default.
- W2101706072 hasPrimaryLocation W21017060721 @default.
- W2101706072 hasRelatedWork W1977631102 @default.
- W2101706072 hasRelatedWork W2007485252 @default.
- W2101706072 hasRelatedWork W2034518652 @default.
- W2101706072 hasRelatedWork W2040191638 @default.
- W2101706072 hasRelatedWork W2074563996 @default.
- W2101706072 hasRelatedWork W2112043533 @default.
- W2101706072 hasRelatedWork W2121497437 @default.
- W2101706072 hasRelatedWork W2139314114 @default.
- W2101706072 hasRelatedWork W2279034697 @default.