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• W2101761958 abstract "In the current study, the quantification of C-reactive protein (CRP) in cerebrospinal fluid (CSF) of dogs using an adapted time-resolved immunofluorimetric assay (TR-IFMA) was investigated, as well as whether the assay could be used to detect the range of CRP concentrations found in different clinical situations. Intra- and interassay coefficients of variation were below 15% in all cases. The TR-IFMA measured the CRP values in a proportional and linear manner ( r = 0.99); also CRP concentrations measured in CSF and in serum were significantly correlated ( r = 0.80, P = 0.003). The limit of detection of the method was 7.1 × 10 −6 mg/l. The assay was able to detect differences in CRP concentrations in CSF of dogs with inflammatory disorders compared with dogs with spinal cord compression or idiopathic epilepsy. In conclusion, TR-IFMA constitutes a very sensitive, precise, and accurate method for the measurement of CRP concentrations in CSF." @default.
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• W2101761958 date "2011-01-01" @default.
• W2101761958 modified "2023-10-16" @default.
• W2101761958 title "Canine C-Reactive Protein Measurements in Cerebrospinal Fluid by a Time-Resolved Immunofluorimetric Assay" @default.
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• W2101761958 doi "https://doi.org/10.1177/104063871102300109" @default.
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