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- W2101821627 abstract "In an experimental animal model the influence of intraarticularly injected high-molecular hyaluronic acid on the healing of superficial and deep lesions of the articular cartilage in freely mobile and immobilized joints was investigated. In the right knee joint in 42 adult rabbits two intracartilaginous lesions were produced in one of the femoral condyles and an osteochondral lesion in the other. In half of the animals the injured knee joint was immobilized in plaster of Paris, while the other half were allowed to move the joint freely. Half of the injured joints in each group were then injected with high-molecular hyaluronic acid once a week for 8 weeks. After 2 months the knee joints were examined histologically, histochemically and microangio-graphically and the water content of the articular cartilage was determined. The intracartilaginous lesions remained unchanged in all knee joints. The wound margins of the osteochondral lesions showed better closure in the immobilized animals. As a rule the osteoc..." @default.
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- W2101821627 date "1978-01-01" @default.
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- W2101821627 title "The Healing of Cartilage Injuries Under the Influence of Joint Immobilization and Repeated Hyaluronic Acid Injections:An Experimental Study" @default.
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- W2101821627 doi "https://doi.org/10.3109/17453677809005737" @default.
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