Matches in SemOpenAlex for { <https://semopenalex.org/work/W2101832805> ?p ?o ?g. }
- W2101832805 endingPage "20130016" @default.
- W2101832805 startingPage "20130016" @default.
- W2101832805 abstract "Asymmetric cell divisions (ACDs) result in two unequal daughter cells and are a hallmark of stem cells. ACDs can be achieved either by asymmetric partitioning of proteins and organelles or by asymmetric cell fate acquisition due to the microenvironment in which the daughters are placed. Increasing evidence suggests that in the mammalian epidermis, both of these processes occur. During embryonic epidermal development, changes occur in the orientation of the mitotic spindle in relation to the underlying basement membrane. These changes are guided by conserved molecular machinery that is operative in lower eukaryotes and dictates asymmetric partitioning of proteins during cell divisions. That said, the shift in spindle alignment also determines whether a division will be parallel or perpendicular to the basement membrane, and this in turn provides a differential microenvironment for the resulting daughter cells. Here, we review how oriented divisions of progenitors contribute to the development and stratification of the epidermis." @default.
- W2101832805 created "2016-06-24" @default.
- W2101832805 creator A5014504040 @default.
- W2101832805 creator A5029089146 @default.
- W2101832805 date "2013-11-05" @default.
- W2101832805 modified "2023-10-18" @default.
- W2101832805 title "Spindle orientation and epidermal morphogenesis" @default.
- W2101832805 cites W1502837338 @default.
- W2101832805 cites W1573053105 @default.
- W2101832805 cites W1578975528 @default.
- W2101832805 cites W1595817144 @default.
- W2101832805 cites W1935003487 @default.
- W2101832805 cites W1940631202 @default.
- W2101832805 cites W1964614947 @default.
- W2101832805 cites W1968956851 @default.
- W2101832805 cites W1969252152 @default.
- W2101832805 cites W1972518538 @default.
- W2101832805 cites W1974059924 @default.
- W2101832805 cites W1976964790 @default.
- W2101832805 cites W1978968660 @default.
- W2101832805 cites W1979812265 @default.
- W2101832805 cites W1980597609 @default.
- W2101832805 cites W1980743267 @default.
- W2101832805 cites W1982337820 @default.
- W2101832805 cites W1984113070 @default.
- W2101832805 cites W1987514898 @default.
- W2101832805 cites W1989415637 @default.
- W2101832805 cites W1990577046 @default.
- W2101832805 cites W1992570015 @default.
- W2101832805 cites W2001947684 @default.
- W2101832805 cites W2004714825 @default.
- W2101832805 cites W2006097513 @default.
- W2101832805 cites W2009022543 @default.
- W2101832805 cites W2009495925 @default.
- W2101832805 cites W2009611668 @default.
- W2101832805 cites W2009685064 @default.
- W2101832805 cites W2013258020 @default.
- W2101832805 cites W2014543214 @default.
- W2101832805 cites W2015155360 @default.
- W2101832805 cites W2015495840 @default.
- W2101832805 cites W2019593540 @default.
- W2101832805 cites W202179075 @default.
- W2101832805 cites W2025434913 @default.
- W2101832805 cites W2026387669 @default.
- W2101832805 cites W2027384096 @default.
- W2101832805 cites W2028489893 @default.
- W2101832805 cites W2036355011 @default.
- W2101832805 cites W2038970717 @default.
- W2101832805 cites W2040667056 @default.
- W2101832805 cites W2041879343 @default.
- W2101832805 cites W2042397019 @default.
- W2101832805 cites W2047921488 @default.
- W2101832805 cites W2050688574 @default.
- W2101832805 cites W2051221246 @default.
- W2101832805 cites W2055721324 @default.
- W2101832805 cites W2056690014 @default.
- W2101832805 cites W2057968441 @default.
- W2101832805 cites W2068727148 @default.
- W2101832805 cites W2075524078 @default.
- W2101832805 cites W2077182790 @default.
- W2101832805 cites W2077638073 @default.
- W2101832805 cites W2078775310 @default.
- W2101832805 cites W2080064943 @default.
- W2101832805 cites W2086265207 @default.
- W2101832805 cites W2086810512 @default.
- W2101832805 cites W2091404816 @default.
- W2101832805 cites W2093778390 @default.
- W2101832805 cites W2095394548 @default.
- W2101832805 cites W2097899984 @default.
- W2101832805 cites W2099059205 @default.
- W2101832805 cites W2101028856 @default.
- W2101832805 cites W2109380828 @default.
- W2101832805 cites W2112973000 @default.
- W2101832805 cites W2113701486 @default.
- W2101832805 cites W2120891538 @default.
- W2101832805 cites W2123179372 @default.
- W2101832805 cites W2125713094 @default.
- W2101832805 cites W2129165079 @default.
- W2101832805 cites W2129260289 @default.
- W2101832805 cites W2136808082 @default.
- W2101832805 cites W2137240069 @default.
- W2101832805 cites W2139240348 @default.
- W2101832805 cites W2152422855 @default.
- W2101832805 cites W2157253543 @default.
- W2101832805 cites W2160680240 @default.
- W2101832805 cites W2167142138 @default.
- W2101832805 cites W2171909588 @default.
- W2101832805 doi "https://doi.org/10.1098/rstb.2013.0016" @default.
- W2101832805 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3785966" @default.
- W2101832805 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24062586" @default.
- W2101832805 hasPublicationYear "2013" @default.
- W2101832805 type Work @default.
- W2101832805 sameAs 2101832805 @default.
- W2101832805 citedByCount "63" @default.
- W2101832805 countsByYear W21018328052013 @default.
- W2101832805 countsByYear W21018328052014 @default.
- W2101832805 countsByYear W21018328052015 @default.
- W2101832805 countsByYear W21018328052016 @default.