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- W2101960751 abstract "Bioassay-guided fractionation of the stems of Spatholobus suberectus led to the isolation of procyanidin B4 (= (+)-catechin-(4-->8)-(-)-epicatechin) (1) and (+)-catechin-(4-->8)-(+)-catechin-(4-->8)-(-)-epicatechin (2). These compounds, isolated before from other sources, were found to be highly potent inhibitors of DNA-topoisomerase-II (Topo-II)-mediated KDNA decatenation, with IC50 values of 22.5+/-2.3 and 21.9+/-2.2 nM, resp." @default.
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- W2101960751 date "2007-07-01" @default.
- W2101960751 modified "2023-10-16" @default.
- W2101960751 title "Topoisomerase-II-Inhibitory Principles from the Stems ofSpatholobus suberectus" @default.
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- W2101960751 doi "https://doi.org/10.1002/cbdv.200790127" @default.
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