FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102012621> ?p ?o ?g. }

• W2102012621 endingPage "281" @default.
• W2102012621 startingPage "271" @default.
• W2102012621 abstract "Imatinib mesylate (Gleevec), Glivec, formerly STI571; Novartis Pharma AG; Basel, Switzerland) is a rationally-designed, molecularly-specific oral anticancer agent that selectively inhibits several protein tyrosine kinases central to the pathogenesis of human cancer. It has demonstrated remarkable clinical efficacy in patients with chronic myeloid leukemia and malignant gastrointestinal stromal tumors. Treatment with imatinib is generally well tolerated, and the risk for severe adverse effects is low. Adverse effects most commonly include mild-to-moderate edema, nausea and vomiting, diarrhea, muscle cramps, and cutaneous reactions. Hepatic transaminase level elevations and myelosuppression occur less frequently and resolve with interruption of imatinib therapy. In general, the incidence and severity of adverse effects tend to correlate with imatinib dose and, in chronic myeloid leukemia patients, the phase of disease; but, patient age and other factors are also associated with some types of reactions. With prompt and appropriate intervention, adverse effects in imatinib-treated patients have proven to be manageable across the spectrum of severity, and they seldom require permanent cessation of therapy. Dose reduction is not usually necessary, and reduction to subtherapeutic levels is not recommended." @default.
• W2102012621 created "2016-06-24" @default.
• W2102012621 creator A5079181777 @default.
• W2102012621 date "2004-06-01" @default.
• W2102012621 modified "2023-10-12" @default.
• W2102012621 title "Indications for Imatinib Mesylate Therapy and Clinical Management" @default.
• W2102012621 cites W1974121953 @default.
• W2102012621 cites W1977892253 @default.
• W2102012621 cites W1978330466 @default.
• W2102012621 cites W1982659189 @default.
• W2102012621 cites W1982734686 @default.
• W2102012621 cites W1995930366 @default.
• W2102012621 cites W1997499809 @default.
• W2102012621 cites W2000629172 @default.
• W2102012621 cites W2008486345 @default.
• W2102012621 cites W2010195142 @default.
• W2102012621 cites W2010735589 @default.
• W2102012621 cites W2011474502 @default.
• W2102012621 cites W2012952884 @default.
• W2102012621 cites W2013850642 @default.
• W2102012621 cites W2015015957 @default.
• W2102012621 cites W2015551422 @default.
• W2102012621 cites W2017469964 @default.
• W2102012621 cites W2025693394 @default.
• W2102012621 cites W2028680409 @default.
• W2102012621 cites W2028959752 @default.
• W2102012621 cites W2030154801 @default.
• W2102012621 cites W2036047439 @default.
• W2102012621 cites W2039045990 @default.
• W2102012621 cites W2040691927 @default.
• W2102012621 cites W2042723332 @default.
• W2102012621 cites W2048142147 @default.
• W2102012621 cites W2064698668 @default.
• W2102012621 cites W2068133101 @default.
• W2102012621 cites W2079446921 @default.
• W2102012621 cites W2084384393 @default.
• W2102012621 cites W2084972182 @default.
• W2102012621 cites W2091653492 @default.
• W2102012621 cites W2102444887 @default.
• W2102012621 cites W2115423630 @default.
• W2102012621 cites W2139248078 @default.
• W2102012621 cites W2142969636 @default.
• W2102012621 cites W2151968496 @default.
• W2102012621 cites W2157610459 @default.
• W2102012621 cites W2169593238 @default.
• W2102012621 cites W2171722798 @default.
• W2102012621 cites W2312804644 @default.
• W2102012621 cites W2312950522 @default.
• W2102012621 cites W2317624504 @default.
• W2102012621 cites W2329648702 @default.
• W2102012621 cites W2546949964 @default.
• W2102012621 cites W2548581615 @default.
• W2102012621 cites W4235458680 @default.
• W2102012621 doi "https://doi.org/10.1634/theoncologist.9-3-271" @default.
• W2102012621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15169982" @default.
• W2102012621 hasPublicationYear "2004" @default.
• W2102012621 type Work @default.
• W2102012621 sameAs 2102012621 @default.
• W2102012621 citedByCount "161" @default.
• W2102012621 countsByYear W21020126212012 @default.
• W2102012621 countsByYear W21020126212013 @default.
• W2102012621 countsByYear W21020126212014 @default.
• W2102012621 countsByYear W21020126212015 @default.
• W2102012621 countsByYear W21020126212016 @default.
• W2102012621 countsByYear W21020126212017 @default.
• W2102012621 countsByYear W21020126212018 @default.
• W2102012621 countsByYear W21020126212019 @default.
• W2102012621 countsByYear W21020126212020 @default.
• W2102012621 countsByYear W21020126212021 @default.
• W2102012621 countsByYear W21020126212022 @default.
• W2102012621 countsByYear W21020126212023 @default.
• W2102012621 crossrefType "journal-article" @default.
• W2102012621 hasAuthorship W2102012621A5079181777 @default.
• W2102012621 hasBestOaLocation W21020126211 @default.
• W2102012621 hasConcept C121608353 @default.
• W2102012621 hasConcept C126322002 @default.
• W2102012621 hasConcept C143998085 @default.
• W2102012621 hasConcept C197934379 @default.
• W2102012621 hasConcept C2777583451 @default.
• W2102012621 hasConcept C2778729363 @default.
• W2102012621 hasConcept C2778820342 @default.
• W2102012621 hasConcept C2780580376 @default.
• W2102012621 hasConcept C3019892230 @default.
• W2102012621 hasConcept C71924100 @default.
• W2102012621 hasConcept C90924648 @default.
• W2102012621 hasConcept C98274493 @default.
• W2102012621 hasConceptScore W2102012621C121608353 @default.
• W2102012621 hasConceptScore W2102012621C126322002 @default.
• W2102012621 hasConceptScore W2102012621C143998085 @default.
• W2102012621 hasConceptScore W2102012621C197934379 @default.
• W2102012621 hasConceptScore W2102012621C2777583451 @default.
• W2102012621 hasConceptScore W2102012621C2778729363 @default.
• W2102012621 hasConceptScore W2102012621C2778820342 @default.
• W2102012621 hasConceptScore W2102012621C2780580376 @default.
• W2102012621 hasConceptScore W2102012621C3019892230 @default.
• W2102012621 hasConceptScore W2102012621C71924100 @default.
• W2102012621 hasConceptScore W2102012621C90924648 @default.
• W2102012621 hasConceptScore W2102012621C98274493 @default.

• next