FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102068103> ?p ?o ?g. }

• W2102068103 endingPage "778" @default.
• W2102068103 startingPage "773" @default.
• W2102068103 abstract "Hepatitis B virus (HBV) causes acute and chronic hepatitis and hepatocellular carcinoma. Although a preventive vaccine is available, the therapeutic options for chronically infected patients are limited. It has been shown that RNA interference can prevent HBV gene expression and replication in vivo when HBV expression vectors are delivered simultaneously with small interfering RNA (siRNA) or siRNA expression constructs. However, the therapeutic potential of siRNAs to interrupt ongoing HBV replication in vivo has not been established. Here, we show that expression of HBV-specific siRNAs in the liver of HBV transgenic mice by recombinant adenoviruses can suppress preexisting HBV gene expression and replication to almost undetectable levels for at least 26 days. These results demonstrate that efficiently delivered siRNAs should be able to silence HBV in chronically infected patients." @default.
• W2102068103 created "2016-06-24" @default.
• W2102068103 creator A5006606436 @default.
• W2102068103 creator A5045662260 @default.
• W2102068103 creator A5058643917 @default.
• W2102068103 creator A5077195292 @default.
• W2102068103 date "2005-01-07" @default.
• W2102068103 modified "2023-10-03" @default.
• W2102068103 title "Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs" @default.
• W2102068103 cites W1933670444 @default.
• W2102068103 cites W1971316234 @default.
• W2102068103 cites W1974303227 @default.
• W2102068103 cites W1976027235 @default.
• W2102068103 cites W1991977041 @default.
• W2102068103 cites W1995677833 @default.
• W2102068103 cites W1995870311 @default.
• W2102068103 cites W2019678529 @default.
• W2102068103 cites W2020328212 @default.
• W2102068103 cites W2021273278 @default.
• W2102068103 cites W2026123650 @default.
• W2102068103 cites W2029653860 @default.
• W2102068103 cites W2037402545 @default.
• W2102068103 cites W2038783205 @default.
• W2102068103 cites W2038992316 @default.
• W2102068103 cites W2072823316 @default.
• W2102068103 cites W2087988279 @default.
• W2102068103 cites W2088650511 @default.
• W2102068103 cites W2089042502 @default.
• W2102068103 cites W2089262366 @default.
• W2102068103 cites W2094281312 @default.
• W2102068103 cites W2099956255 @default.
• W2102068103 cites W2101273158 @default.
• W2102068103 cites W2102238490 @default.
• W2102068103 cites W2134812217 @default.
• W2102068103 cites W2140412749 @default.
• W2102068103 cites W2149610637 @default.
• W2102068103 cites W2158110042 @default.
• W2102068103 cites W2162511575 @default.
• W2102068103 cites W2166293484 @default.
• W2102068103 cites W2166504564 @default.
• W2102068103 cites W2168944129 @default.
• W2102068103 cites W2171109371 @default.
• W2102068103 cites W4248653169 @default.
• W2102068103 cites W4253422011 @default.
• W2102068103 cites W4294216491 @default.
• W2102068103 doi "https://doi.org/10.1073/pnas.0409028102" @default.
• W2102068103 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/545555" @default.
• W2102068103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15640346" @default.
• W2102068103 hasPublicationYear "2005" @default.
• W2102068103 type Work @default.
• W2102068103 sameAs 2102068103 @default.
• W2102068103 citedByCount "181" @default.
• W2102068103 countsByYear W21020681032012 @default.
• W2102068103 countsByYear W21020681032013 @default.
• W2102068103 countsByYear W21020681032014 @default.
• W2102068103 countsByYear W21020681032015 @default.
• W2102068103 countsByYear W21020681032016 @default.
• W2102068103 countsByYear W21020681032017 @default.
• W2102068103 countsByYear W21020681032018 @default.
• W2102068103 countsByYear W21020681032019 @default.
• W2102068103 countsByYear W21020681032020 @default.
• W2102068103 countsByYear W21020681032021 @default.
• W2102068103 countsByYear W21020681032023 @default.
• W2102068103 crossrefType "journal-article" @default.
• W2102068103 hasAuthorship W2102068103A5006606436 @default.
• W2102068103 hasAuthorship W2102068103A5045662260 @default.
• W2102068103 hasAuthorship W2102068103A5058643917 @default.
• W2102068103 hasAuthorship W2102068103A5077195292 @default.
• W2102068103 hasBestOaLocation W21020681031 @default.
• W2102068103 hasConcept C102230213 @default.
• W2102068103 hasConcept C104317684 @default.
• W2102068103 hasConcept C119056186 @default.
• W2102068103 hasConcept C140704245 @default.
• W2102068103 hasConcept C150194340 @default.
• W2102068103 hasConcept C150903083 @default.
• W2102068103 hasConcept C159047783 @default.
• W2102068103 hasConcept C166703698 @default.
• W2102068103 hasConcept C190232843 @default.
• W2102068103 hasConcept C194575299 @default.
• W2102068103 hasConcept C207001950 @default.
• W2102068103 hasConcept C22615655 @default.
• W2102068103 hasConcept C2522874641 @default.
• W2102068103 hasConcept C2778019345 @default.
• W2102068103 hasConcept C2780593183 @default.
• W2102068103 hasConcept C502942594 @default.
• W2102068103 hasConcept C55493867 @default.
• W2102068103 hasConcept C67705224 @default.
• W2102068103 hasConcept C71924100 @default.
• W2102068103 hasConcept C73616013 @default.
• W2102068103 hasConcept C86803240 @default.
• W2102068103 hasConceptScore W2102068103C102230213 @default.
• W2102068103 hasConceptScore W2102068103C104317684 @default.
• W2102068103 hasConceptScore W2102068103C119056186 @default.
• W2102068103 hasConceptScore W2102068103C140704245 @default.
• W2102068103 hasConceptScore W2102068103C150194340 @default.
• W2102068103 hasConceptScore W2102068103C150903083 @default.
• W2102068103 hasConceptScore W2102068103C159047783 @default.
• W2102068103 hasConceptScore W2102068103C166703698 @default.

• next