FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102069080> ?p ?o ?g. }

• W2102069080 endingPage "477" @default.
• W2102069080 startingPage "468" @default.
• W2102069080 abstract "In this study, based on a rat model of human environmental exposure to cadmium (Cd), it has been examined whether low-level lifetime Cd exposure increases the risk of vertebral osteoporosis and vertebrae fractures in the elderly. For this purpose, the lumbar vertebral bodies (L4 or L3) of control and Cd-exposed (1 mg Cd/l in drinking water for 24 months) female Wistar rats were assigned to densitometric, radiographic, biomechanical (compression test), and biochemical studies, as well as to assess their dimensions and chemical composition. The exposure to Cd affected the mineral status of the L4. The decreased mineral content, density (BMD) and bone mineral area of the vertebral body together with the unchanged ratio of non-organic and organic components indicate osteoporotic nature of the Cd-induced changes. The activity of alkaline phosphatase in the L3 decreased. Cd also influenced the mechanical properties of the L4. The yield load and ultimate load decreased indicating a weakness in the vertebral body compression strength. Stiffness of the L4 decreased and the displacement at ultimate increased suggesting its enhanced susceptibility to deformities. Indeed, in the Cd group vertebral deformities (in 30% of females) or even fractures (in 40% of females), including those with disruption of bone continuity were evident. Z-score values for the L4 BMD revealed vertebral osteopenia in 30% and osteoporosis in 70% of the Cd-exposed females. The results allow for the conclusion that low lifetime exposure to Cd may become an important factor increasing the risk of lumbar spine osteoporosis with vertebral deformities and fractures in the elderly." @default.
• W2102069080 created "2016-06-24" @default.
• W2102069080 creator A5011280137 @default.
• W2102069080 creator A5061221781 @default.
• W2102069080 date "2004-09-16" @default.
• W2102069080 modified "2023-10-16" @default.
• W2102069080 title "Low-Level Exposure to Cadmium during the Lifetime Increases the Risk of Osteoporosis and Fractures of the Lumbar Spine in the Elderly: Studies on a Rat Model of Human Environmental Exposure" @default.
• W2102069080 cites W1491753771 @default.
• W2102069080 cites W1970400080 @default.
• W2102069080 cites W1981734815 @default.
• W2102069080 cites W1987809980 @default.
• W2102069080 cites W1993612260 @default.
• W2102069080 cites W1999456817 @default.
• W2102069080 cites W2004611729 @default.
• W2102069080 cites W2005554742 @default.
• W2102069080 cites W2006553971 @default.
• W2102069080 cites W2010728661 @default.
• W2102069080 cites W2011105081 @default.
• W2102069080 cites W2018201683 @default.
• W2102069080 cites W2025466158 @default.
• W2102069080 cites W2032097545 @default.
• W2102069080 cites W2033968745 @default.
• W2102069080 cites W2034356964 @default.
• W2102069080 cites W2037175164 @default.
• W2102069080 cites W2037360623 @default.
• W2102069080 cites W2052777858 @default.
• W2102069080 cites W2059512302 @default.
• W2102069080 cites W2062113640 @default.
• W2102069080 cites W2062933352 @default.
• W2102069080 cites W2070134813 @default.
• W2102069080 cites W2071670812 @default.
• W2102069080 cites W2073309533 @default.
• W2102069080 cites W2082080986 @default.
• W2102069080 cites W2085076607 @default.
• W2102069080 cites W2085313044 @default.
• W2102069080 cites W2102131116 @default.
• W2102069080 cites W2122745505 @default.
• W2102069080 cites W2125042609 @default.
• W2102069080 cites W2135372180 @default.
• W2102069080 cites W2141877446 @default.
• W2102069080 cites W2171981975 @default.
• W2102069080 cites W4253751532 @default.
• W2102069080 doi "https://doi.org/10.1093/toxsci/kfh275" @default.
• W2102069080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15375291" @default.
• W2102069080 hasPublicationYear "2004" @default.
• W2102069080 type Work @default.
• W2102069080 sameAs 2102069080 @default.
• W2102069080 citedByCount "80" @default.
• W2102069080 countsByYear W21020690802012 @default.
• W2102069080 countsByYear W21020690802013 @default.
• W2102069080 countsByYear W21020690802014 @default.
• W2102069080 countsByYear W21020690802015 @default.
• W2102069080 countsByYear W21020690802016 @default.
• W2102069080 countsByYear W21020690802017 @default.
• W2102069080 countsByYear W21020690802018 @default.
• W2102069080 countsByYear W21020690802019 @default.
• W2102069080 countsByYear W21020690802020 @default.
• W2102069080 countsByYear W21020690802021 @default.
• W2102069080 countsByYear W21020690802022 @default.
• W2102069080 countsByYear W21020690802023 @default.
• W2102069080 crossrefType "journal-article" @default.
• W2102069080 hasAuthorship W2102069080A5011280137 @default.
• W2102069080 hasAuthorship W2102069080A5061221781 @default.
• W2102069080 hasBestOaLocation W21020690801 @default.
• W2102069080 hasConcept C105702510 @default.
• W2102069080 hasConcept C126322002 @default.
• W2102069080 hasConcept C134018914 @default.
• W2102069080 hasConcept C141071460 @default.
• W2102069080 hasConcept C178790620 @default.
• W2102069080 hasConcept C185592680 @default.
• W2102069080 hasConcept C2776541429 @default.
• W2102069080 hasConcept C2776886416 @default.
• W2102069080 hasConcept C2777083390 @default.
• W2102069080 hasConcept C2779835254 @default.
• W2102069080 hasConcept C3017433307 @default.
• W2102069080 hasConcept C42407357 @default.
• W2102069080 hasConcept C44575665 @default.
• W2102069080 hasConcept C544657597 @default.
• W2102069080 hasConcept C71924100 @default.
• W2102069080 hasConceptScore W2102069080C105702510 @default.
• W2102069080 hasConceptScore W2102069080C126322002 @default.
• W2102069080 hasConceptScore W2102069080C134018914 @default.
• W2102069080 hasConceptScore W2102069080C141071460 @default.
• W2102069080 hasConceptScore W2102069080C178790620 @default.
• W2102069080 hasConceptScore W2102069080C185592680 @default.
• W2102069080 hasConceptScore W2102069080C2776541429 @default.
• W2102069080 hasConceptScore W2102069080C2776886416 @default.
• W2102069080 hasConceptScore W2102069080C2777083390 @default.
• W2102069080 hasConceptScore W2102069080C2779835254 @default.
• W2102069080 hasConceptScore W2102069080C3017433307 @default.
• W2102069080 hasConceptScore W2102069080C42407357 @default.
• W2102069080 hasConceptScore W2102069080C44575665 @default.
• W2102069080 hasConceptScore W2102069080C544657597 @default.
• W2102069080 hasConceptScore W2102069080C71924100 @default.
• W2102069080 hasIssue "2" @default.
• W2102069080 hasLocation W21020690801 @default.
• W2102069080 hasLocation W21020690802 @default.
• W2102069080 hasLocation W21020690803 @default.

• next