Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102156745> ?p ?o ?g. }
- W2102156745 endingPage "1049" @default.
- W2102156745 startingPage "1038" @default.
- W2102156745 abstract "ABSTRACT Biosynthesis of the variable core domain of lipooligosaccharide (LOS) in Neisseria gonorrhoeae is mediated by glycosyl transferases encoded by lgtABCDE . Changes within homopolymeric runs within lgtA , lgtC , and lgtD affect the expression state of these genes, with the nature of the LOS expressed determined by the functionality of these genes. However, the mechanism for modulating the amount of multiple LOS chemotypes expressed in a single cell is not understood. Using mutants containing polar disruptions within the lgtABCDE locus, we determined that the expression of this locus is mediated by multiple promoters and that disruption of transcription from these promoters alters the relative levels of simultaneously expressed LOS chemotypes. Expression of the lgtABCDE locus was quantified by using xylE transcriptional fusions, and the data indicate that this locus is transcribed in trace amounts and that subtle changes in transcription result in phenotypic changes. By using rapid amplification of 5′ cDNA ends, transcriptional start sites and promoter sequences were identified within lgtABCDE . Most of these promoters possessed 50 to 67% homology with the consensus gearbox promoter sequence of Escherichia coli ." @default.
- W2102156745 created "2016-06-24" @default.
- W2102156745 creator A5048750558 @default.
- W2102156745 creator A5079145539 @default.
- W2102156745 date "2004-02-15" @default.
- W2102156745 modified "2023-10-14" @default.
- W2102156745 title "The <i>lgtABCDE</i> Gene Cluster, Involved in Lipooligosaccharide Biosynthesis in <i>Neisseria gonorrhoeae</i> , Contains Multiple Promoter Sequences" @default.
- W2102156745 cites W1494346402 @default.
- W2102156745 cites W1509104544 @default.
- W2102156745 cites W1558783117 @default.
- W2102156745 cites W1700106312 @default.
- W2102156745 cites W1826475507 @default.
- W2102156745 cites W1839239199 @default.
- W2102156745 cites W1840917369 @default.
- W2102156745 cites W1905745227 @default.
- W2102156745 cites W1918492382 @default.
- W2102156745 cites W1922098314 @default.
- W2102156745 cites W1922471182 @default.
- W2102156745 cites W1951083500 @default.
- W2102156745 cites W1967164846 @default.
- W2102156745 cites W1967855647 @default.
- W2102156745 cites W1978090129 @default.
- W2102156745 cites W1981749404 @default.
- W2102156745 cites W1994790587 @default.
- W2102156745 cites W1999851893 @default.
- W2102156745 cites W2014751502 @default.
- W2102156745 cites W2019410656 @default.
- W2102156745 cites W2028313821 @default.
- W2102156745 cites W2034674930 @default.
- W2102156745 cites W2035053848 @default.
- W2102156745 cites W2057591873 @default.
- W2102156745 cites W2060810530 @default.
- W2102156745 cites W2065334867 @default.
- W2102156745 cites W2068750760 @default.
- W2102156745 cites W2092010381 @default.
- W2102156745 cites W2096562757 @default.
- W2102156745 cites W2098304400 @default.
- W2102156745 cites W2102531352 @default.
- W2102156745 cites W2102659193 @default.
- W2102156745 cites W2103321738 @default.
- W2102156745 cites W2111719241 @default.
- W2102156745 cites W2119271974 @default.
- W2102156745 cites W2131206962 @default.
- W2102156745 cites W2131946761 @default.
- W2102156745 cites W2132284765 @default.
- W2102156745 cites W2135911787 @default.
- W2102156745 cites W2139652313 @default.
- W2102156745 cites W2139739499 @default.
- W2102156745 cites W2145036189 @default.
- W2102156745 cites W2145458242 @default.
- W2102156745 cites W2147685178 @default.
- W2102156745 cites W2159703694 @default.
- W2102156745 cites W2167921125 @default.
- W2102156745 cites W2168432889 @default.
- W2102156745 cites W2169859503 @default.
- W2102156745 cites W2302327121 @default.
- W2102156745 cites W4233464453 @default.
- W2102156745 cites W4247292500 @default.
- W2102156745 cites W4293247451 @default.
- W2102156745 doi "https://doi.org/10.1128/jb.186.4.1038-1049.2004" @default.
- W2102156745 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/344203" @default.
- W2102156745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14761998" @default.
- W2102156745 hasPublicationYear "2004" @default.
- W2102156745 type Work @default.
- W2102156745 sameAs 2102156745 @default.
- W2102156745 citedByCount "15" @default.
- W2102156745 countsByYear W21021567452012 @default.
- W2102156745 countsByYear W21021567452014 @default.
- W2102156745 countsByYear W21021567452016 @default.
- W2102156745 countsByYear W21021567452018 @default.
- W2102156745 countsByYear W21021567452019 @default.
- W2102156745 countsByYear W21021567452020 @default.
- W2102156745 crossrefType "journal-article" @default.
- W2102156745 hasAuthorship W2102156745A5048750558 @default.
- W2102156745 hasAuthorship W2102156745A5079145539 @default.
- W2102156745 hasBestOaLocation W21021567451 @default.
- W2102156745 hasConcept C101762097 @default.
- W2102156745 hasConcept C104317684 @default.
- W2102156745 hasConcept C138885662 @default.
- W2102156745 hasConcept C150194340 @default.
- W2102156745 hasConcept C153911025 @default.
- W2102156745 hasConcept C179926584 @default.
- W2102156745 hasConcept C187882448 @default.
- W2102156745 hasConcept C36857842 @default.
- W2102156745 hasConcept C41895202 @default.
- W2102156745 hasConcept C54355233 @default.
- W2102156745 hasConcept C84597430 @default.
- W2102156745 hasConcept C86803240 @default.
- W2102156745 hasConceptScore W2102156745C101762097 @default.
- W2102156745 hasConceptScore W2102156745C104317684 @default.
- W2102156745 hasConceptScore W2102156745C138885662 @default.
- W2102156745 hasConceptScore W2102156745C150194340 @default.
- W2102156745 hasConceptScore W2102156745C153911025 @default.
- W2102156745 hasConceptScore W2102156745C179926584 @default.
- W2102156745 hasConceptScore W2102156745C187882448 @default.
- W2102156745 hasConceptScore W2102156745C36857842 @default.
- W2102156745 hasConceptScore W2102156745C41895202 @default.
- W2102156745 hasConceptScore W2102156745C54355233 @default.