FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102171609> ?p ?o ?g. }

• W2102171609 abstract "The World Health Organisation estimates that by 2030 there will be approximately 350 million people with type 2 diabetes. Associated with renal complications, heart disease, stroke and peripheral vascular disease, early identification of patients with undiagnosed type 2 diabetes or those at an increased risk of developing type 2 diabetes is an important challenge. We sought to systematically review and critically assess the conduct and reporting of methods used to develop risk prediction models for predicting the risk of having undiagnosed (prevalent) or future risk of developing (incident) type 2 diabetes in adults. We conducted a systematic search of PubMed and EMBASE databases to identify studies published before May 2011 that describe the development of models combining two or more variables to predict the risk of prevalent or incident type 2 diabetes. We extracted key information that describes aspects of developing a prediction model including study design, sample size and number of events, outcome definition, risk predictor selection and coding, missing data, model-building strategies and aspects of performance. Thirty-nine studies comprising 43 risk prediction models were included. Seventeen studies (44%) reported the development of models to predict incident type 2 diabetes, whilst 15 studies (38%) described the derivation of models to predict prevalent type 2 diabetes. In nine studies (23%), the number of events per variable was less than ten, whilst in fourteen studies there was insufficient information reported for this measure to be calculated. The number of candidate risk predictors ranged from four to sixty-four, and in seven studies it was unclear how many risk predictors were considered. A method, not recommended to select risk predictors for inclusion in the multivariate model, using statistical significance from univariate screening was carried out in eight studies (21%), whilst the selection procedure was unclear in ten studies (26%). Twenty-one risk prediction models (49%) were developed by categorising all continuous risk predictors. The treatment and handling of missing data were not reported in 16 studies (41%). We found widespread use of poor methods that could jeopardise model development, including univariate pre-screening of variables, categorisation of continuous risk predictors and poor handling of missing data. The use of poor methods affects the reliability of the prediction model and ultimately compromises the accuracy of the probability estimates of having undiagnosed type 2 diabetes or the predicted risk of developing type 2 diabetes. In addition, many studies were characterised by a generally poor level of reporting, with many key details to objectively judge the usefulness of the models often omitted." @default.
• W2102171609 created "2016-06-24" @default.
• W2102171609 creator A5000161839 @default.
• W2102171609 creator A5045695482 @default.
• W2102171609 creator A5060891981 @default.
• W2102171609 creator A5089744545 @default.
• W2102171609 date "2011-09-08" @default.
• W2102171609 modified "2023-10-07" @default.
• W2102171609 title "Developing risk prediction models for type 2 diabetes: a systematic review of methodology and reporting" @default.
• W2102171609 cites W105168457 @default.
• W2102171609 cites W1502728206 @default.
• W2102171609 cites W1518248815 @default.
• W2102171609 cites W1529485074 @default.
• W2102171609 cites W1602443498 @default.
• W2102171609 cites W1658165688 @default.
• W2102171609 cites W1827722585 @default.
• W2102171609 cites W1977822083 @default.
• W2102171609 cites W1982245010 @default.
• W2102171609 cites W1987806755 @default.
• W2102171609 cites W1988375742 @default.
• W2102171609 cites W1988825111 @default.
• W2102171609 cites W1992595212 @default.
• W2102171609 cites W1993119975 @default.
• W2102171609 cites W1994059850 @default.
• W2102171609 cites W1994822962 @default.
• W2102171609 cites W2008075020 @default.
• W2102171609 cites W2012301002 @default.
• W2102171609 cites W2013972803 @default.
• W2102171609 cites W2020016182 @default.
• W2102171609 cites W2031400294 @default.
• W2102171609 cites W2034381211 @default.
• W2102171609 cites W2037126859 @default.
• W2102171609 cites W2037195555 @default.
• W2102171609 cites W2037668591 @default.
• W2102171609 cites W2039265044 @default.
• W2102171609 cites W2040958097 @default.
• W2102171609 cites W2041033959 @default.
• W2102171609 cites W2045366734 @default.
• W2102171609 cites W2048325728 @default.
• W2102171609 cites W2049103906 @default.
• W2102171609 cites W2050546713 @default.
• W2102171609 cites W2059483607 @default.
• W2102171609 cites W2060932845 @default.
• W2102171609 cites W2064352562 @default.
• W2102171609 cites W2064799866 @default.
• W2102171609 cites W2067920033 @default.
• W2102171609 cites W2070161901 @default.
• W2102171609 cites W2072026981 @default.
• W2102171609 cites W2073970954 @default.
• W2102171609 cites W2074475130 @default.
• W2102171609 cites W2075937340 @default.
• W2102171609 cites W2077553676 @default.
• W2102171609 cites W2079084616 @default.
• W2102171609 cites W2081562657 @default.
• W2102171609 cites W2082376914 @default.
• W2102171609 cites W2082600072 @default.
• W2102171609 cites W2086274453 @default.
• W2102171609 cites W2089428346 @default.
• W2102171609 cites W2094050483 @default.
• W2102171609 cites W2094104004 @default.
• W2102171609 cites W2096672909 @default.
• W2102171609 cites W2099351652 @default.
• W2102171609 cites W2101568662 @default.
• W2102171609 cites W2103556204 @default.
• W2102171609 cites W2106734747 @default.
• W2102171609 cites W2109325327 @default.
• W2102171609 cites W2111319065 @default.
• W2102171609 cites W2116020076 @default.
• W2102171609 cites W2116170563 @default.
• W2102171609 cites W2118047689 @default.
• W2102171609 cites W2120624839 @default.
• W2102171609 cites W2121054444 @default.
• W2102171609 cites W2125419095 @default.
• W2102171609 cites W2126436234 @default.
• W2102171609 cites W2129390900 @default.
• W2102171609 cites W2129845479 @default.
• W2102171609 cites W2129925362 @default.
• W2102171609 cites W2132951487 @default.
• W2102171609 cites W2133103557 @default.
• W2102171609 cites W2134646525 @default.
• W2102171609 cites W2139609011 @default.
• W2102171609 cites W2139842191 @default.
• W2102171609 cites W2141922524 @default.
• W2102171609 cites W2143517695 @default.
• W2102171609 cites W2147615711 @default.
• W2102171609 cites W2150691612 @default.
• W2102171609 cites W2151166219 @default.
• W2102171609 cites W2156098321 @default.
• W2102171609 cites W2158810997 @default.
• W2102171609 cites W2160237323 @default.
• W2102171609 cites W2164949078 @default.
• W2102171609 cites W2165786903 @default.
• W2102171609 cites W2494169975 @default.
• W2102171609 cites W2991792334 @default.
• W2102171609 cites W3022423927 @default.
• W2102171609 cites W4236805817 @default.
• W2102171609 cites W4237870467 @default.
• W2102171609 cites W4255569342 @default.
• W2102171609 cites W4321428130 @default.
• W2102171609 doi "https://doi.org/10.1186/1741-7015-9-103" @default.

• next