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- W2102220797 abstract "SUMMARY Models of the macronucleus in Paramecium tetraurelia which assume known levels of ploidy and random segregation of subunits smaller than a haploid set at both fission and macronuclear regeneration (MR) are not consistent with the hypothesis that senescence is due to aneuploid imbalance. Either senescence has some other basis or there is a mechanism for regular distribution of subunits at MR. Random segregation models for fission and MR are consistent with most data on survival and heterozygote stability, but if the ploidy level is 860 they fail to account for the data of Nyberg (this volume). Since the ploidy level may be higher than 860, models of random segregation cannot be ruled out for Paramecium . Models of the macronucleus in hypotrichs which assume randomly segregating chromosome fragments are consistent with data on survival and on stability of heterozygous genotypes at fission." @default.
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- W2102220797 title "Quantitative predictions of random segregation models of the ciliate macronucleus" @default.
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- W2102220797 doi "https://doi.org/10.1017/s0016672300016426" @default.
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