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• W2102247923 abstract "ABSTRACT Macrolide resistance is a major concern in the treatment of Streptococcus pneumoniae . Inducible macrolide resistance in this pneumococcus is mediated by the efflux pump MefE/Mel. We show here that the human antimicrobial peptide LL-37 induces the mefE promoter and confers resistance to erythromycin and LL-37. Such induction may impact the efficacy of host defenses and of macrolide-based treatment of pneumococcal disease." @default.
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• W2102247923 date "2010-08-01" @default.
• W2102247923 modified "2023-10-16" @default.
• W2102247923 title "Human Antimicrobial Peptide LL-37 Induces MefE/Mel-Mediated Macrolide Resistance in <i>Streptococcus pneumoniae</i>" @default.
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• W2102247923 doi "https://doi.org/10.1128/aac.01756-09" @default.
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