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• W2102332610 endingPage "395" @default.
• W2102332610 startingPage "369" @default.
• W2102332610 abstract "This review evaluates the available information on the effects of mainstream and environmental tobacco smoke on the immune system in animals and humans. The primary emphasis is on mainstream smoke since little information is available on the effects of environmental smoke. The effects of mainstream tobacco smoke on the immune system in humans and animals are similar. Animals exposed to mainstream tobacco smoke for periods of a few weeks generally exhibit a slight immunostimulation. However, subchronic and chronic exposure studies indicate that immunosuppressive changes develop. Lymphocyte proliferation in response to the mitogens PHA and LPS is decreased, suggesting compromise of cell function. Antibody production can be suppressed. Smoke-exposed animals that are challenged with metastasizing tumors or viruses have been shown to exhibit a higher incidence of tumorigenic and infectious diseases, respectively. Localized immunological changes in the lung can include reduction of bronchus-associated lymphoid tissue and immunoglobulin levels. Smoking-related changes in the peripheral immune system of humans have included elevated WBC counts, increased cytotoxic/suppressor and decreased inducer/helper T-cell numbers, slightly suppressed T-lymphocyte activity, significantly decreased natural killer cell activity, lowered circulating immunoglobin titers, except for IgE which is elevated, and increased susceptibility to infection. The effects of environmental tobacco smoke on the immune system, in contrast to mainstream tobacco smoke, have just begun to be investigated and information available in the literature, to date, is limited. Immunoreactive substances are known to be present in environmental tobacco smoke, but to date, environmental tobacco smoke has been more closely associated with irritation than sensitization. A few studies have indicated a potential for environmental smoke-induced hypersensitivity and suppression of immunoregulatory substances. In contrast, other investigators have failed to detect immunological or other biological changes associated with environmental smoke. Clearly, more research is needed to resolve these differences." @default.
• W2102332610 created "2016-06-24" @default.
• W2102332610 creator A5020836851 @default.
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• W2102332610 creator A5080055434 @default.
• W2102332610 creator A5040662610 @default.
• W2102332610 date "1990-01-01" @default.
• W2102332610 modified "2023-09-30" @default.
• W2102332610 title "Effects of Mainstream and Environmental Tobacco Smoke on the Immune System in Animals and Humans: A Review" @default.
• W2102332610 cites W1510350052 @default.
• W2102332610 cites W1523441199 @default.
• W2102332610 cites W1569269680 @default.
• W2102332610 cites W1608835056 @default.
• W2102332610 cites W171793030 @default.
• W2102332610 cites W1753071495 @default.
• W2102332610 cites W1766816711 @default.
• W2102332610 cites W1785800095 @default.
• W2102332610 cites W1823901267 @default.
• W2102332610 cites W183798622 @default.
• W2102332610 cites W1845797841 @default.
• W2102332610 cites W1895159060 @default.
• W2102332610 cites W1925072096 @default.
• W2102332610 cites W1943050136 @default.
• W2102332610 cites W1965848820 @default.
• W2102332610 cites W1965896310 @default.
• W2102332610 cites W1966949072 @default.
• W2102332610 cites W1967967481 @default.
• W2102332610 cites W1968309027 @default.
• W2102332610 cites W1968310666 @default.
• W2102332610 cites W1969989534 @default.
• W2102332610 cites W1970022617 @default.
• W2102332610 cites W1972321566 @default.
• W2102332610 cites W1975642620 @default.
• W2102332610 cites W1978174334 @default.
• W2102332610 cites W1979162100 @default.
• W2102332610 cites W1979973487 @default.
• W2102332610 cites W1982460203 @default.
• W2102332610 cites W1982950743 @default.
• W2102332610 cites W1986283478 @default.
• W2102332610 cites W1987564386 @default.
• W2102332610 cites W1989282999 @default.
• W2102332610 cites W1993161179 @default.
• W2102332610 cites W1993256799 @default.
• W2102332610 cites W1994267460 @default.
• W2102332610 cites W1994978485 @default.
• W2102332610 cites W1995117236 @default.
• W2102332610 cites W1997290862 @default.
• W2102332610 cites W2000122746 @default.
• W2102332610 cites W2000983790 @default.
• W2102332610 cites W2003116722 @default.
• W2102332610 cites W2003208274 @default.
• W2102332610 cites W2004479194 @default.
• W2102332610 cites W2008487198 @default.
• W2102332610 cites W2009225058 @default.
• W2102332610 cites W2011582754 @default.
• W2102332610 cites W2012539964 @default.
• W2102332610 cites W2013000107 @default.
• W2102332610 cites W2013285607 @default.
• W2102332610 cites W2013401623 @default.
• W2102332610 cites W2014297616 @default.
• W2102332610 cites W2016518309 @default.
• W2102332610 cites W2017988610 @default.
• W2102332610 cites W2018038778 @default.
• W2102332610 cites W2020458932 @default.
• W2102332610 cites W2021542773 @default.
• W2102332610 cites W2023336870 @default.
• W2102332610 cites W2024974345 @default.
• W2102332610 cites W2025842638 @default.
• W2102332610 cites W2026405511 @default.
• W2102332610 cites W2027009151 @default.
• W2102332610 cites W2028932038 @default.
• W2102332610 cites W2031533974 @default.
• W2102332610 cites W2032233319 @default.
• W2102332610 cites W2032821919 @default.
• W2102332610 cites W2032987971 @default.
• W2102332610 cites W2037096406 @default.
• W2102332610 cites W2038241725 @default.
• W2102332610 cites W2040353642 @default.
• W2102332610 cites W2040836277 @default.
• W2102332610 cites W2041128134 @default.
• W2102332610 cites W2042732838 @default.
• W2102332610 cites W2045181279 @default.
• W2102332610 cites W2045332813 @default.
• W2102332610 cites W2047132424 @default.
• W2102332610 cites W2047714110 @default.
• W2102332610 cites W2048033034 @default.
• W2102332610 cites W2049171756 @default.
• W2102332610 cites W2050327326 @default.
• W2102332610 cites W2050400697 @default.
• W2102332610 cites W2050806482 @default.
• W2102332610 cites W2050915379 @default.
• W2102332610 cites W2052662255 @default.
• W2102332610 cites W2054866041 @default.
• W2102332610 cites W2056572740 @default.
• W2102332610 cites W2057073021 @default.
• W2102332610 cites W2060604807 @default.
• W2102332610 cites W2062757790 @default.

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