FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102364600> ?p ?o ?g. }

• W2102364600 endingPage "817" @default.
• W2102364600 startingPage "809" @default.
• W2102364600 abstract "We previously reported that interleukin (IL)-4 treatment of nonobese diabetic (NOD) mice elevates intrapancreatic CCL4 expression and protects from type 1 diabetes. Here, we show that antibody neutralization of CCL4 abrogates the ability of T-cells from IL-4-treated NOD mice to transfer protection against type 1 diabetes. Intradermal delivery of CCL4 via a plasmid vector stabilized by incorporation of the Epstein-Barr virus EBNA1/oriP episomal maintenance replicon (pHERO8100-CCL4) to NOD mice beginning at later stages of disease progression protects against type 1 diabetes. This protection was associated with a Th2-like response in the spleen and pancreas; decreased recruitment of activated CD8(+) T-cells to islets, accompanied by diminished CCR5 expression on CD8(+) T-cells; and regulatory T-cell activity in the draining pancreatic lymph nodes. Thus, inflammatory responses that target islet beta-cells are suppressed by CCL4, which implicates the use of CCL4 therapeutically to prevent type 1 diabetes." @default.
• W2102364600 created "2016-06-24" @default.
• W2102364600 creator A5010662010 @default.
• W2102364600 creator A5012899459 @default.
• W2102364600 creator A5017739524 @default.
• W2102364600 creator A5019368786 @default.
• W2102364600 creator A5024832913 @default.
• W2102364600 creator A5044587467 @default.
• W2102364600 creator A5048623216 @default.
• W2102364600 creator A5057470948 @default.
• W2102364600 creator A5076317415 @default.
• W2102364600 date "2007-03-01" @default.
• W2102364600 modified "2023-09-27" @default.
• W2102364600 title "CCL4 Protects From Type 1 Diabetes by Altering Islet β-Cell–Targeted Inflammatory Responses" @default.
• W2102364600 cites W1480207260 @default.
• W2102364600 cites W1526621387 @default.
• W2102364600 cites W1530522871 @default.
• W2102364600 cites W1608842679 @default.
• W2102364600 cites W1672597967 @default.
• W2102364600 cites W1929224014 @default.
• W2102364600 cites W1964367916 @default.
• W2102364600 cites W1966288604 @default.
• W2102364600 cites W1972714276 @default.
• W2102364600 cites W1975105353 @default.
• W2102364600 cites W1986865394 @default.
• W2102364600 cites W1991173254 @default.
• W2102364600 cites W1992986960 @default.
• W2102364600 cites W1994837807 @default.
• W2102364600 cites W1996087599 @default.
• W2102364600 cites W2001433846 @default.
• W2102364600 cites W2028107523 @default.
• W2102364600 cites W2057898581 @default.
• W2102364600 cites W2071756824 @default.
• W2102364600 cites W2090098475 @default.
• W2102364600 cites W2099945349 @default.
• W2102364600 cites W2106109092 @default.
• W2102364600 cites W2110300596 @default.
• W2102364600 cites W2113764136 @default.
• W2102364600 cites W2117644665 @default.
• W2102364600 cites W2128699224 @default.
• W2102364600 cites W2130273718 @default.
• W2102364600 cites W2134486617 @default.
• W2102364600 cites W2144040204 @default.
• W2102364600 cites W2423298231 @default.
• W2102364600 cites W4247055279 @default.
• W2102364600 cites W4313333870 @default.
• W2102364600 doi "https://doi.org/10.2337/db06-0619" @default.
• W2102364600 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17327452" @default.
• W2102364600 hasPublicationYear "2007" @default.
• W2102364600 type Work @default.
• W2102364600 sameAs 2102364600 @default.
• W2102364600 citedByCount "32" @default.
• W2102364600 countsByYear W21023646002012 @default.
• W2102364600 countsByYear W21023646002013 @default.
• W2102364600 countsByYear W21023646002014 @default.
• W2102364600 countsByYear W21023646002015 @default.
• W2102364600 countsByYear W21023646002016 @default.
• W2102364600 countsByYear W21023646002018 @default.
• W2102364600 countsByYear W21023646002019 @default.
• W2102364600 countsByYear W21023646002020 @default.
• W2102364600 countsByYear W21023646002021 @default.
• W2102364600 countsByYear W21023646002022 @default.
• W2102364600 crossrefType "journal-article" @default.
• W2102364600 hasAuthorship W2102364600A5010662010 @default.
• W2102364600 hasAuthorship W2102364600A5012899459 @default.
• W2102364600 hasAuthorship W2102364600A5017739524 @default.
• W2102364600 hasAuthorship W2102364600A5019368786 @default.
• W2102364600 hasAuthorship W2102364600A5024832913 @default.
• W2102364600 hasAuthorship W2102364600A5044587467 @default.
• W2102364600 hasAuthorship W2102364600A5048623216 @default.
• W2102364600 hasAuthorship W2102364600A5057470948 @default.
• W2102364600 hasAuthorship W2102364600A5076317415 @default.
• W2102364600 hasBestOaLocation W21023646001 @default.
• W2102364600 hasConcept C102124568 @default.
• W2102364600 hasConcept C126322002 @default.
• W2102364600 hasConcept C134018914 @default.
• W2102364600 hasConcept C165220095 @default.
• W2102364600 hasConcept C167672396 @default.
• W2102364600 hasConcept C178790620 @default.
• W2102364600 hasConcept C185592680 @default.
• W2102364600 hasConcept C203014093 @default.
• W2102364600 hasConcept C2776828364 @default.
• W2102364600 hasConcept C2777359374 @default.
• W2102364600 hasConcept C2778013207 @default.
• W2102364600 hasConcept C2778764654 @default.
• W2102364600 hasConcept C2779511750 @default.
• W2102364600 hasConcept C2780931953 @default.
• W2102364600 hasConcept C2781232474 @default.
• W2102364600 hasConcept C555293320 @default.
• W2102364600 hasConcept C55851684 @default.
• W2102364600 hasConcept C71924100 @default.
• W2102364600 hasConcept C86803240 @default.
• W2102364600 hasConcept C8891405 @default.
• W2102364600 hasConceptScore W2102364600C102124568 @default.
• W2102364600 hasConceptScore W2102364600C126322002 @default.
• W2102364600 hasConceptScore W2102364600C134018914 @default.
• W2102364600 hasConceptScore W2102364600C165220095 @default.
• W2102364600 hasConceptScore W2102364600C167672396 @default.

• next