Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102392317> ?p ?o ?g. }
- W2102392317 endingPage "1214" @default.
- W2102392317 startingPage "1210" @default.
- W2102392317 abstract "With the use of combination antiretroviral therapy, the proportion of HIV-infected patients over age 50 has greatly increased. The rate of progression of untreated HIV disease, response to therapy and complicating effects of co-morbidities differ in older versus younger patients. Compared with younger individuals, older untreated HIV patients demonstrate faster rates of CD4+ cell loss and more rapid progression to AIDS and death. With treatment, older patients have a better virological response, but a less robust immunological response. The treatment of older HIV-infected patients is further complicated by pre-existing co-morbid conditions including cardiovascular, hepatic and metabolic complications that may be exacerbated by the effects of HIV infection per se, modest immunodeficiency (i.e. at CD4+ counts >350 cells/mm3), and the metabolic and other adverse effects of combination antiretroviral therapy. Based on these considerations guidelines for the treatment of HIV-infected patients state that increased age is a consideration in initiating antiretroviral therapy in persons with >350–500 CD4+ cells/mm3." @default.
- W2102392317 created "2016-06-24" @default.
- W2102392317 creator A5008116183 @default.
- W2102392317 creator A5066209540 @default.
- W2102392317 date "2011-03-18" @default.
- W2102392317 modified "2023-10-01" @default.
- W2102392317 title "Complications of HIV infection in an ageing population: challenges in managing older patients on long-term combination antiretroviral therapy" @default.
- W2102392317 cites W1522239606 @default.
- W2102392317 cites W1550604532 @default.
- W2102392317 cites W1586408319 @default.
- W2102392317 cites W1597248718 @default.
- W2102392317 cites W1606409921 @default.
- W2102392317 cites W1767400858 @default.
- W2102392317 cites W1983455184 @default.
- W2102392317 cites W1986281714 @default.
- W2102392317 cites W1989415380 @default.
- W2102392317 cites W1990410878 @default.
- W2102392317 cites W1993015636 @default.
- W2102392317 cites W1997919632 @default.
- W2102392317 cites W1999208986 @default.
- W2102392317 cites W2000210076 @default.
- W2102392317 cites W2000962191 @default.
- W2102392317 cites W2003293061 @default.
- W2102392317 cites W2006498349 @default.
- W2102392317 cites W2008304011 @default.
- W2102392317 cites W2013541138 @default.
- W2102392317 cites W2025740330 @default.
- W2102392317 cites W2027816509 @default.
- W2102392317 cites W2032364679 @default.
- W2102392317 cites W2032448658 @default.
- W2102392317 cites W2050999867 @default.
- W2102392317 cites W2054641701 @default.
- W2102392317 cites W2056779298 @default.
- W2102392317 cites W2071463698 @default.
- W2102392317 cites W2080152031 @default.
- W2102392317 cites W2080861496 @default.
- W2102392317 cites W2082494671 @default.
- W2102392317 cites W2083751424 @default.
- W2102392317 cites W2086893453 @default.
- W2102392317 cites W2093888975 @default.
- W2102392317 cites W2095716220 @default.
- W2102392317 cites W2110717475 @default.
- W2102392317 cites W2111064211 @default.
- W2102392317 cites W2113750343 @default.
- W2102392317 cites W2118627939 @default.
- W2102392317 cites W2134198866 @default.
- W2102392317 cites W2135120233 @default.
- W2102392317 cites W2140437973 @default.
- W2102392317 cites W2145677576 @default.
- W2102392317 cites W2146780540 @default.
- W2102392317 cites W2148314152 @default.
- W2102392317 cites W2153136696 @default.
- W2102392317 cites W2157894496 @default.
- W2102392317 cites W2158666805 @default.
- W2102392317 cites W2164059021 @default.
- W2102392317 cites W2166168319 @default.
- W2102392317 cites W2166535756 @default.
- W2102392317 cites W2167865974 @default.
- W2102392317 cites W2171153361 @default.
- W2102392317 cites W2236174386 @default.
- W2102392317 cites W2321526788 @default.
- W2102392317 cites W2748171261 @default.
- W2102392317 cites W4240153861 @default.
- W2102392317 cites W83931366 @default.
- W2102392317 doi "https://doi.org/10.1093/jac/dkr058" @default.
- W2102392317 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21421583" @default.
- W2102392317 hasPublicationYear "2011" @default.
- W2102392317 type Work @default.
- W2102392317 sameAs 2102392317 @default.
- W2102392317 citedByCount "20" @default.
- W2102392317 countsByYear W21023923172012 @default.
- W2102392317 countsByYear W21023923172013 @default.
- W2102392317 countsByYear W21023923172014 @default.
- W2102392317 countsByYear W21023923172015 @default.
- W2102392317 countsByYear W21023923172016 @default.
- W2102392317 countsByYear W21023923172017 @default.
- W2102392317 countsByYear W21023923172018 @default.
- W2102392317 countsByYear W21023923172019 @default.
- W2102392317 countsByYear W21023923172021 @default.
- W2102392317 countsByYear W21023923172022 @default.
- W2102392317 crossrefType "journal-article" @default.
- W2102392317 hasAuthorship W2102392317A5008116183 @default.
- W2102392317 hasAuthorship W2102392317A5066209540 @default.
- W2102392317 hasConcept C126322002 @default.
- W2102392317 hasConcept C142462285 @default.
- W2102392317 hasConcept C179755657 @default.
- W2102392317 hasConcept C197934379 @default.
- W2102392317 hasConcept C203014093 @default.
- W2102392317 hasConcept C2908647359 @default.
- W2102392317 hasConcept C2993143319 @default.
- W2102392317 hasConcept C3013748606 @default.
- W2102392317 hasConcept C500440147 @default.
- W2102392317 hasConcept C500499127 @default.
- W2102392317 hasConcept C71924100 @default.
- W2102392317 hasConcept C99454951 @default.
- W2102392317 hasConceptScore W2102392317C126322002 @default.
- W2102392317 hasConceptScore W2102392317C142462285 @default.
- W2102392317 hasConceptScore W2102392317C179755657 @default.