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• W2102450838 abstract "A simple facile synthesis of substituted purine derivatives has been developed by using Mitsunobu conditions for an alcohol and a respective nucleobase. A wide range of alcohols produces good to excellent yield (>90%). The resulting purine analogues show good regioselectivity with N-9 substitution as the dominant products in most of the cases. Application of diastereospecific alcohols reveals a complete inversion of the carbon stereogenic center giving a single diastereomer. More than two dozen novel nucleobase derivatives have been prepared in high yield." @default.
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• W2102450838 date "2007-05-25" @default.
• W2102450838 modified "2023-10-16" @default.
• W2102450838 title "Mitsunobu Coupling of Nucleobases and Alcohols: An Efficient, Practical Synthesis for Novel Nonsugar Carbon Nucleosides" @default.
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• W2102450838 doi "https://doi.org/10.1021/jo070515+" @default.
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