FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102479195> ?p ?o ?g. }

• W2102479195 endingPage "861" @default.
• W2102479195 startingPage "845" @default.
• W2102479195 abstract "Neuronal dysfunction and degeneration are central events of a number of major diseases with significant unmet need. Neuronal dysfunction may not necessarily be the result of cell death, but may also be due to synaptic damage leading to impaired neuronal cell signaling or long-term potentiation. Once degeneration occurs, it is unclear whether axonal or synaptic loss comes first or whether this precedes neuronal cell death. In this review we summarize the pathophysiology of four major neurodegenerative diseases; Alzheimer’s disease, Parkinson’s disease, multiple sclerosis and amyotrophic lateral sclerosis (Lou Gehrig’s disease) For each of these diseases, we describe how biochemical biomarkers are currently understood in relation to the pathophysiology and in terms of neuronal biology, and we discuss the clinical and diagnostic utility of these potential tools, which are at present limited. We discuss how markers may be used to drive drug development and clinical practice." @default.
• W2102479195 created "2016-06-24" @default.
• W2102479195 creator A5021603048 @default.
• W2102479195 creator A5040065277 @default.
• W2102479195 date "2013-11-01" @default.
• W2102479195 modified "2023-10-03" @default.
• W2102479195 title "Molecular biomarkers of neurodegeneration" @default.
• W2102479195 cites W1516808086 @default.
• W2102479195 cites W1527671059 @default.
• W2102479195 cites W1558795029 @default.
• W2102479195 cites W1776482002 @default.
• W2102479195 cites W1878976622 @default.
• W2102479195 cites W1963880027 @default.
• W2102479195 cites W1964599349 @default.
• W2102479195 cites W1965453486 @default.
• W2102479195 cites W1965552163 @default.
• W2102479195 cites W1966120362 @default.
• W2102479195 cites W1966868208 @default.
• W2102479195 cites W1967471680 @default.
• W2102479195 cites W1967473627 @default.
• W2102479195 cites W1969219973 @default.
• W2102479195 cites W1971073983 @default.
• W2102479195 cites W1972617504 @default.
• W2102479195 cites W1972618253 @default.
• W2102479195 cites W1974247973 @default.
• W2102479195 cites W1974535033 @default.
• W2102479195 cites W1980171878 @default.
• W2102479195 cites W1981236273 @default.
• W2102479195 cites W1981929653 @default.
• W2102479195 cites W1982535961 @default.
• W2102479195 cites W1983135764 @default.
• W2102479195 cites W1983660498 @default.
• W2102479195 cites W1984069677 @default.
• W2102479195 cites W1984377299 @default.
• W2102479195 cites W1985582661 @default.
• W2102479195 cites W1985703940 @default.
• W2102479195 cites W1986774440 @default.
• W2102479195 cites W1987057401 @default.
• W2102479195 cites W1988494453 @default.
• W2102479195 cites W1990442094 @default.
• W2102479195 cites W1990752558 @default.
• W2102479195 cites W1992768136 @default.
• W2102479195 cites W1994343280 @default.
• W2102479195 cites W1995096439 @default.
• W2102479195 cites W1996363835 @default.
• W2102479195 cites W1997874814 @default.
• W2102479195 cites W1998678315 @default.
• W2102479195 cites W1999159261 @default.
• W2102479195 cites W1999644289 @default.
• W2102479195 cites W2000980666 @default.
• W2102479195 cites W2001301483 @default.
• W2102479195 cites W2001477615 @default.
• W2102479195 cites W2003260773 @default.
• W2102479195 cites W2008767130 @default.
• W2102479195 cites W2008827081 @default.
• W2102479195 cites W2009573330 @default.
• W2102479195 cites W2009860575 @default.
• W2102479195 cites W2010455335 @default.
• W2102479195 cites W2014287294 @default.
• W2102479195 cites W2014483271 @default.
• W2102479195 cites W2015299782 @default.
• W2102479195 cites W2015494537 @default.
• W2102479195 cites W2015667893 @default.
• W2102479195 cites W2015876677 @default.
• W2102479195 cites W2016317003 @default.
• W2102479195 cites W2019709557 @default.
• W2102479195 cites W2020925047 @default.
• W2102479195 cites W2021041558 @default.
• W2102479195 cites W2021352595 @default.
• W2102479195 cites W2021404217 @default.
• W2102479195 cites W2021996506 @default.
• W2102479195 cites W2026158140 @default.
• W2102479195 cites W2026676471 @default.
• W2102479195 cites W2026863482 @default.
• W2102479195 cites W2028296452 @default.
• W2102479195 cites W2028846933 @default.
• W2102479195 cites W2030827315 @default.
• W2102479195 cites W2033132890 @default.
• W2102479195 cites W2034300008 @default.
• W2102479195 cites W2039449904 @default.
• W2102479195 cites W2039958870 @default.
• W2102479195 cites W2040358504 @default.
• W2102479195 cites W2041857757 @default.
• W2102479195 cites W2042650337 @default.
• W2102479195 cites W2044566123 @default.
• W2102479195 cites W2045826874 @default.
• W2102479195 cites W2048213146 @default.
• W2102479195 cites W2050676526 @default.
• W2102479195 cites W2051501993 @default.
• W2102479195 cites W2052111329 @default.
• W2102479195 cites W2052151366 @default.
• W2102479195 cites W2052908754 @default.
• W2102479195 cites W2056465861 @default.
• W2102479195 cites W2058371877 @default.
• W2102479195 cites W2062441068 @default.
• W2102479195 cites W2066897444 @default.
• W2102479195 cites W2068011527 @default.
• W2102479195 cites W2068037239 @default.

• next