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• W2102496723 abstract "Ribosome profiling is a technique that permits genome-wide, quantitative analysis of translation and has found broad application in recent years. Here we describe a modified profiling protocol and software package designed to benefit more broadly the translation community in terms of simplicity and utility. The protocol, applicable to diverse organisms, including organelles, is based largely on previously published profiling methodologies, but uses duplex-specific nuclease (DSN) as a convenient, species-independent way to reduce rRNA contamination. We show that DSN-based depletion compares favorably with other commonly used rRNA depletion strategies and introduces little bias. The profiling protocol typically produces high levels of triplet periodicity, facilitating the detection of coding sequences, including upstream, downstream, and overlapping open reading frames (ORFs) and an alternative ribosome conformation evident during termination of protein synthesis. In addition, we provide a software package that presents a set of methods for parsing ribosomal profiling data from multiple samples, aligning reads to coding sequences, inferring alternative ORFs, and plotting average and transcript-specific aspects of the data. Methods are also provided for extracting the data in a form suitable for differential analysis of translation and translational efficiency." @default.
• W2102496723 created "2016-06-24" @default.
• W2102496723 creator A5003756828 @default.
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• W2102496723 creator A5046652547 @default.
• W2102496723 creator A5050195392 @default.
• W2102496723 creator A5056217079 @default.
• W2102496723 date "2015-08-18" @default.
• W2102496723 modified "2023-10-12" @default.
• W2102496723 title "The use of duplex-specific nuclease in ribosome profiling and a user-friendly software package for Ribo-seq data analysis" @default.
• W2102496723 cites W1208971950 @default.
• W2102496723 cites W1278468206 @default.
• W2102496723 cites W1481679225 @default.
• W2102496723 cites W1521051093 @default.
• W2102496723 cites W1527392350 @default.
• W2102496723 cites W1561855928 @default.
• W2102496723 cites W170656348 @default.
• W2102496723 cites W1799375255 @default.
• W2102496723 cites W1916447021 @default.
• W2102496723 cites W1963396472 @default.
• W2102496723 cites W1967308537 @default.
• W2102496723 cites W1972677800 @default.
• W2102496723 cites W1980179012 @default.
• W2102496723 cites W1980438612 @default.
• W2102496723 cites W1982790821 @default.
• W2102496723 cites W1988001471 @default.
• W2102496723 cites W1989621875 @default.
• W2102496723 cites W1992308820 @default.
• W2102496723 cites W1993848026 @default.
• W2102496723 cites W1999293853 @default.
• W2102496723 cites W2003861150 @default.
• W2102496723 cites W2010005720 @default.
• W2102496723 cites W2010201702 @default.
• W2102496723 cites W2012759636 @default.
• W2102496723 cites W2019362237 @default.
• W2102496723 cites W2021795499 @default.
• W2102496723 cites W2023374667 @default.
• W2102496723 cites W2029905838 @default.
• W2102496723 cites W2030555025 @default.
• W2102496723 cites W2031341022 @default.
• W2102496723 cites W2031861189 @default.
• W2102496723 cites W2033492309 @default.
• W2102496723 cites W2038254017 @default.
• W2102496723 cites W2057015366 @default.
• W2102496723 cites W2057850601 @default.
• W2102496723 cites W2058838088 @default.
• W2102496723 cites W2058852389 @default.
• W2102496723 cites W2060508829 @default.
• W2102496723 cites W2071849521 @default.
• W2102496723 cites W2077408229 @default.
• W2102496723 cites W2079517684 @default.
• W2102496723 cites W2079656901 @default.
• W2102496723 cites W2082047304 @default.
• W2102496723 cites W2084561418 @default.
• W2102496723 cites W2085533843 @default.
• W2102496723 cites W2086157203 @default.
• W2102496723 cites W2091328421 @default.
• W2102496723 cites W2092803829 @default.
• W2102496723 cites W2093236036 @default.
• W2102496723 cites W2096963663 @default.
• W2102496723 cites W2103250001 @default.
• W2102496723 cites W2105575738 @default.
• W2102496723 cites W2108074319 @default.
• W2102496723 cites W2109602972 @default.
• W2102496723 cites W2113506612 @default.
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• W2102496723 cites W2116831267 @default.
• W2102496723 cites W2119708131 @default.
• W2102496723 cites W2124779706 @default.
• W2102496723 cites W2124985265 @default.
• W2102496723 cites W2127848114 @default.
• W2102496723 cites W2127982547 @default.
• W2102496723 cites W2129016585 @default.
• W2102496723 cites W2131360537 @default.
• W2102496723 cites W2133040714 @default.
• W2102496723 cites W2133968430 @default.
• W2102496723 cites W2134028524 @default.
• W2102496723 cites W2139153548 @default.
• W2102496723 cites W2142138683 @default.
• W2102496723 cites W2145477882 @default.
• W2102496723 cites W2146564033 @default.
• W2102496723 cites W2149175672 @default.
• W2102496723 cites W2149792337 @default.
• W2102496723 cites W2152645648 @default.
• W2102496723 cites W2160215304 @default.
• W2102496723 cites W2161897332 @default.
• W2102496723 cites W2163672244 @default.
• W2102496723 cites W2164637416 @default.
• W2102496723 cites W2166847046 @default.
• W2102496723 cites W2167725902 @default.
• W2102496723 cites W2168138973 @default.
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• W2102496723 doi "https://doi.org/10.1261/rna.052548.115" @default.
• W2102496723 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4574750" @default.
• W2102496723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26286745" @default.
• W2102496723 hasPublicationYear "2015" @default.

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