FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102551570> ?p ?o ?g. }

• W2102551570 endingPage "32" @default.
• W2102551570 startingPage "28" @default.
• W2102551570 abstract "Tissue inhibitor of metalloproteinases (TIMP-2) is a low molecular weight proteinase inhibitor capable of inhibiting activated matrix metalloproteinases (MMPs). TIMP-2 is found both free and in a 1:1 stoichiometric complex with the pro-enzyme form of MMP-2 (pro-MMP-2/TIMP-2 complex). We have measured the binding of recombinant TIMP-2 to intact HT-1080 and MCF-7 cells. HT-1080 cells in suspension bound 125I-labeled rTIMP-2 with a Kd of 2.5 nM and 30,000 sites/cell. Monolayers of MCF-7 cells were similarly found to bind [125I]rTIMP-2 with a Kd of 1.6 nM and 25,000 sites/cell. Specific binding of MMP-2 alone to HT-1080 cells was not observed; however, pro-MMP-2/TIMP-2 complex was capable of binding to the surface of HT-1080 cells in a TIMP-2-dependent manner. Binding of rTIMP-2 was not competed by the presence of TIMP-1. These results suggest that rTIMP-2 alone binds directly to the cell surface of HT-1080 and MCF-7 cell lines, and TIMP-2 is capable of localizing MMP-2 to the surface of HT-1080 cells via interaction with a specific binding site." @default.
• W2102551570 created "2016-06-24" @default.
• W2102551570 creator A5010575981 @default.
• W2102551570 creator A5051433481 @default.
• W2102551570 creator A5054112793 @default.
• W2102551570 creator A5062387212 @default.
• W2102551570 creator A5091380477 @default.
• W2102551570 creator A5091806822 @default.
• W2102551570 date "1995-05-01" @default.
• W2102551570 modified "2023-10-16" @default.
• W2102551570 title "Cell surface binding of TIMP-2 and pro-MMP-2/TIMP-2 complex" @default.
• W2102551570 cites W1488746545 @default.
• W2102551570 cites W1549954866 @default.
• W2102551570 cites W1585695184 @default.
• W2102551570 cites W1593920002 @default.
• W2102551570 cites W1602981281 @default.
• W2102551570 cites W1664158328 @default.
• W2102551570 cites W1894541755 @default.
• W2102551570 cites W2000903132 @default.
• W2102551570 cites W2028199718 @default.
• W2102551570 cites W2032226288 @default.
• W2102551570 cites W2070412924 @default.
• W2102551570 cites W2089726055 @default.
• W2102551570 cites W2095498651 @default.
• W2102551570 cites W2109658199 @default.
• W2102551570 cites W2119050264 @default.
• W2102551570 cites W2188357563 @default.
• W2102551570 cites W2395006442 @default.
• W2102551570 cites W34074909 @default.
• W2102551570 cites W4248217916 @default.
• W2102551570 doi "https://doi.org/10.1016/0014-5793(95)00345-a" @default.
• W2102551570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7750537" @default.
• W2102551570 hasPublicationYear "1995" @default.
• W2102551570 type Work @default.
• W2102551570 sameAs 2102551570 @default.
• W2102551570 citedByCount "104" @default.
• W2102551570 countsByYear W21025515702012 @default.
• W2102551570 countsByYear W21025515702013 @default.
• W2102551570 countsByYear W21025515702014 @default.
• W2102551570 countsByYear W21025515702015 @default.
• W2102551570 countsByYear W21025515702016 @default.
• W2102551570 countsByYear W21025515702017 @default.
• W2102551570 countsByYear W21025515702018 @default.
• W2102551570 countsByYear W21025515702019 @default.
• W2102551570 countsByYear W21025515702020 @default.
• W2102551570 countsByYear W21025515702021 @default.
• W2102551570 countsByYear W21025515702022 @default.
• W2102551570 countsByYear W21025515702023 @default.
• W2102551570 crossrefType "journal-article" @default.
• W2102551570 hasAuthorship W2102551570A5010575981 @default.
• W2102551570 hasAuthorship W2102551570A5051433481 @default.
• W2102551570 hasAuthorship W2102551570A5054112793 @default.
• W2102551570 hasAuthorship W2102551570A5062387212 @default.
• W2102551570 hasAuthorship W2102551570A5091380477 @default.
• W2102551570 hasAuthorship W2102551570A5091806822 @default.
• W2102551570 hasConcept C107824862 @default.
• W2102551570 hasConcept C109523444 @default.
• W2102551570 hasConcept C12554922 @default.
• W2102551570 hasConcept C1491633281 @default.
• W2102551570 hasConcept C153911025 @default.
• W2102551570 hasConcept C181199279 @default.
• W2102551570 hasConcept C185592680 @default.
• W2102551570 hasConcept C54355233 @default.
• W2102551570 hasConcept C55493867 @default.
• W2102551570 hasConcept C81885089 @default.
• W2102551570 hasConcept C86803240 @default.
• W2102551570 hasConcept C95444343 @default.
• W2102551570 hasConceptScore W2102551570C107824862 @default.
• W2102551570 hasConceptScore W2102551570C109523444 @default.
• W2102551570 hasConceptScore W2102551570C12554922 @default.
• W2102551570 hasConceptScore W2102551570C1491633281 @default.
• W2102551570 hasConceptScore W2102551570C153911025 @default.
• W2102551570 hasConceptScore W2102551570C181199279 @default.
• W2102551570 hasConceptScore W2102551570C185592680 @default.
• W2102551570 hasConceptScore W2102551570C54355233 @default.
• W2102551570 hasConceptScore W2102551570C55493867 @default.
• W2102551570 hasConceptScore W2102551570C81885089 @default.
• W2102551570 hasConceptScore W2102551570C86803240 @default.
• W2102551570 hasConceptScore W2102551570C95444343 @default.
• W2102551570 hasIssue "1" @default.
• W2102551570 hasLocation W21025515701 @default.
• W2102551570 hasLocation W21025515702 @default.
• W2102551570 hasOpenAccess W2102551570 @default.
• W2102551570 hasPrimaryLocation W21025515701 @default.
• W2102551570 hasRelatedWork W1437588494 @default.
• W2102551570 hasRelatedWork W1850986032 @default.
• W2102551570 hasRelatedWork W1968721630 @default.
• W2102551570 hasRelatedWork W2029732200 @default.
• W2102551570 hasRelatedWork W2080203695 @default.
• W2102551570 hasRelatedWork W2091139028 @default.
• W2102551570 hasRelatedWork W2365587227 @default.
• W2102551570 hasRelatedWork W2380989154 @default.
• W2102551570 hasRelatedWork W3029784168 @default.
• W2102551570 hasRelatedWork W4242974861 @default.
• W2102551570 hasVolume "364" @default.
• W2102551570 isParatext "false" @default.
• W2102551570 isRetracted "false" @default.
• W2102551570 magId "2102551570" @default.

• next