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- W2102556564 abstract "Daily chlorhexidine mouthwash is often recommended for preventing chemotherapy-induced oral mucositis. Povidone-iodine, NaCl 0.9%, water salt soda solution and chamomile mouthwash are also recommended. However, the effectiveness of these mouthwashes is unclear. Therefore, we performed a systematic review to assess the effectiveness of mouthwashes in preventing and ameliorating chemotherapy-induced oral mucositis. Based on study quality, three out of five randomized controlled trials were included in a meta-analysis. The results failed to detect any beneficial effects of chlorhexidine as compared with sterile water, or NaCl 0.9%. Patients complained about negative side-effects of chlorhexidine, including teeth discoloration and alteration of taste in two of the five studies on chlorhexidine. The severity of oral mucositis was shown to be reduced by 30% using a povidone-iodine mouthwash as compared with sterile water in a single randomized controlled trial. These results do not support the use of chlorhexidine mouthwash to prevent oral mucositis." @default.
- W2102556564 created "2016-06-24" @default.
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- W2102556564 date "2006-12-01" @default.
- W2102556564 modified "2023-09-29" @default.
- W2102556564 title "The effectiveness of commonly used mouthwashes for the prevention of chemotherapy-induced oral mucositis: a systematic review" @default.
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- W2102556564 doi "https://doi.org/10.1111/j.1365-2354.2006.00684.x" @default.
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