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• W2102567575 abstract "Abstract This study investigated the effects of glycinin on the growth, intestinal oxidative status, tight junction components, cytokines and apoptosis signalling factors of fish. The results showed that an 80 g/kg diet of glycinin exposure for 42 d caused poor growth performance and depressed intestinal growth and function of juvenile Jian carp ( Cyprinus carpio var. Jian). Meanwhile, dietary glycinin exposure induced increases in lipid peroxidation and protein oxidation; it caused reductions in superoxide dismutase (SOD), catalase and glutathione peroxidase (GPx) activities; and it increased MnSOD, CuZnSOD, GPx1b and GPx4a mRNA levels, suggesting an adaptive mechanism against stress in the intestines of fish. However, dietary glycinin exposure decreased both the activity and mRNA levels of nine isoforms of glutathione- S -transferase ( GST ) ( α , μ , π , ρ , θ , κ , mGST1 , mGST2 and mGST3 ), indicating toxicity to this enzyme activity and corresponding isoform gene expressions. In addition, glycinin exposure caused partial disruption of intestinal cell–cell tight junction components, disturbances of cytokines and induced apoptosis signalling in the distal intestines>mid intestines>proximal intestines of fish. Glycinin exposure also disturbed the mRNA levels of intestinal-related signalling factors Nrf2 , Keap1a , Keap1b , eleven isoforms of protein kinase C and target of rapamycin/ 4E-BP . Interestingly, glutamine was observed to partially block those negative influences. In conclusion, this study indicates that dietary glycinin exposure causes intestinal oxidative damage and disruption of intestinal physical barriers and functions and reduces fish growth, but glutamine can reverse those negative effects in fish. This study provides some information on the mechanism of glycinin-induced negative effects." @default.
• W2102567575 created "2016-06-24" @default.
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• W2102567575 date "2015-09-09" @default.
• W2102567575 modified "2023-10-18" @default.
• W2102567575 title "Soyabean glycinin depresses intestinal growth and function in juvenile Jian carp (<i>Cyprinus carpio</i>var Jian): protective effects of glutamine" @default.
• W2102567575 cites W108928143 @default.
• W2102567575 cites W1539054313 @default.
• W2102567575 cites W1540384225 @default.
• W2102567575 cites W1579085732 @default.
• W2102567575 cites W1861510650 @default.
• W2102567575 cites W1884649135 @default.
• W2102567575 cites W1966397178 @default.
• W2102567575 cites W1966524893 @default.
• W2102567575 cites W1969812442 @default.
• W2102567575 cites W1977945477 @default.
• W2102567575 cites W1978430350 @default.
• W2102567575 cites W1984768507 @default.
• W2102567575 cites W1987228708 @default.
• W2102567575 cites W1989591321 @default.
• W2102567575 cites W1990463098 @default.
• W2102567575 cites W1991190713 @default.
• W2102567575 cites W1993204994 @default.
• W2102567575 cites W1995014650 @default.
• W2102567575 cites W1995445783 @default.
• W2102567575 cites W1996749934 @default.
• W2102567575 cites W1999391945 @default.
• W2102567575 cites W2002106363 @default.
• W2102567575 cites W2004654278 @default.
• W2102567575 cites W2005667801 @default.
• W2102567575 cites W2007991922 @default.
• W2102567575 cites W2009890943 @default.
• W2102567575 cites W2014294861 @default.
• W2102567575 cites W2016647782 @default.
• W2102567575 cites W2018644669 @default.
• W2102567575 cites W2018888672 @default.
• W2102567575 cites W2019254002 @default.
• W2102567575 cites W2020216238 @default.
• W2102567575 cites W2020487253 @default.
• W2102567575 cites W2022045742 @default.
• W2102567575 cites W2023891688 @default.
• W2102567575 cites W2024979614 @default.
• W2102567575 cites W2025578881 @default.
• W2102567575 cites W2027755570 @default.
• W2102567575 cites W2028049959 @default.
• W2102567575 cites W2029921874 @default.
• W2102567575 cites W2032117479 @default.
• W2102567575 cites W2036297991 @default.
• W2102567575 cites W2039253203 @default.
• W2102567575 cites W2039935344 @default.
• W2102567575 cites W2043935380 @default.
• W2102567575 cites W2046910373 @default.
• W2102567575 cites W2048151697 @default.
• W2102567575 cites W2052921747 @default.
• W2102567575 cites W2053919910 @default.
• W2102567575 cites W2061184965 @default.
• W2102567575 cites W2062053430 @default.
• W2102567575 cites W2062198448 @default.
• W2102567575 cites W2062859168 @default.
• W2102567575 cites W2065941658 @default.
• W2102567575 cites W2069102014 @default.
• W2102567575 cites W2069794343 @default.
• W2102567575 cites W2073353302 @default.
• W2102567575 cites W2074867655 @default.
• W2102567575 cites W2077672337 @default.
• W2102567575 cites W2081304453 @default.
• W2102567575 cites W2081974503 @default.
• W2102567575 cites W2085580868 @default.
• W2102567575 cites W2085805621 @default.
• W2102567575 cites W2092568663 @default.
• W2102567575 cites W2094577457 @default.
• W2102567575 cites W2094776252 @default.
• W2102567575 cites W2099035044 @default.
• W2102567575 cites W2099244326 @default.
• W2102567575 cites W2122039020 @default.
• W2102567575 cites W2133538175 @default.
• W2102567575 cites W2156359701 @default.
• W2102567575 cites W2161982997 @default.
• W2102567575 cites W2184366236 @default.
• W2102567575 cites W2952387848 @default.
• W2102567575 cites W2979454297 @default.
• W2102567575 cites W4293247451 @default.
• W2102567575 doi "https://doi.org/10.1017/s0007114515003219" @default.
• W2102567575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26349522" @default.
• W2102567575 hasPublicationYear "2015" @default.
• W2102567575 type Work @default.

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