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- W2102600963 abstract "Endocrine disrupting chemicals (EDC) have received considerable attention as potential obesogens. Past studies examining obesogenic potential of one widespread EDC, bisphenol A (BPA), have generally focused on metabolic and adipose tissue effects. However, physical inactivity has been proposed to be a leading cause of obesity. A paucity of studies has considered whether EDC, including BPA, affects this behavior. To test whether early exposure to BPA and ethinyl estradiol (EE, estrogen present in birth control pills) results in metabolic and such behavioral disruptions, California mice developmentally exposed to BPA and EE were tested as adults for energy expenditure (indirect calorimetry), body composition (echoMRI) and physical activity (measured by beam breaks and voluntary wheel running). Serum glucose and metabolic hormones were measured. No differences in body weight or food consumption were detected. BPA-exposed females exhibited greater variation in weight than females in control and EE groups. During the dark and light cycles, BPA females exhibited a higher average respiratory quotient than control females, indicative of metabolizing carbohydrates rather than fats. Various assessments of voluntary physical activity in the home cage confirmed that during the dark cycle, BPA and EE-exposed females were significantly less active in this setting than control females. Similar effects were not observed in BPA or EE-exposed males. No significant differences were detected in serum glucose, insulin, adiponectin and leptin concentrations. Results suggest that females developmentally exposed to BPA exhibit decreased motivation to engage in voluntary physical activity and altered metabolism of carbohydrates v . fats, which could have important health implications." @default.
- W2102600963 created "2016-06-24" @default.
- W2102600963 creator A5002151933 @default.
- W2102600963 creator A5011431207 @default.
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- W2102600963 creator A5065933684 @default.
- W2102600963 creator A5072471830 @default.
- W2102600963 creator A5090943412 @default.
- W2102600963 date "2015-09-18" @default.
- W2102600963 modified "2023-10-09" @default.
- W2102600963 title "Sex-dependent effects of developmental exposure to bisphenol A and ethinyl estradiol on metabolic parameters and voluntary physical activity" @default.
- W2102600963 cites W1507642220 @default.
- W2102600963 cites W1509262734 @default.
- W2102600963 cites W1510536664 @default.
- W2102600963 cites W1545124358 @default.
- W2102600963 cites W1583176296 @default.
- W2102600963 cites W1956388950 @default.
- W2102600963 cites W1963522150 @default.
- W2102600963 cites W1967211742 @default.
- W2102600963 cites W1967620846 @default.
- W2102600963 cites W1967934360 @default.
- W2102600963 cites W1968179768 @default.
- W2102600963 cites W1969191244 @default.
- W2102600963 cites W1970358298 @default.
- W2102600963 cites W1970760886 @default.
- W2102600963 cites W1972649268 @default.
- W2102600963 cites W1973017097 @default.
- W2102600963 cites W1975752932 @default.
- W2102600963 cites W1976655780 @default.
- W2102600963 cites W1979456059 @default.
- W2102600963 cites W1986018940 @default.
- W2102600963 cites W1986661245 @default.
- W2102600963 cites W1987797208 @default.
- W2102600963 cites W1990322878 @default.
- W2102600963 cites W1991027805 @default.
- W2102600963 cites W1992386938 @default.
- W2102600963 cites W1993062385 @default.
- W2102600963 cites W1997342739 @default.
- W2102600963 cites W1997480783 @default.
- W2102600963 cites W1997576256 @default.
- W2102600963 cites W2000209446 @default.
- W2102600963 cites W2001441224 @default.
- W2102600963 cites W2001872368 @default.
- W2102600963 cites W2003187314 @default.
- W2102600963 cites W2003636092 @default.
- W2102600963 cites W2007586461 @default.
- W2102600963 cites W2007888807 @default.
- W2102600963 cites W2010862738 @default.
- W2102600963 cites W2014266108 @default.
- W2102600963 cites W2014865123 @default.
- W2102600963 cites W2015008373 @default.
- W2102600963 cites W2017707375 @default.
- W2102600963 cites W2018381563 @default.
- W2102600963 cites W2018910489 @default.
- W2102600963 cites W2024201289 @default.
- W2102600963 cites W2025292518 @default.
- W2102600963 cites W2027600022 @default.
- W2102600963 cites W2029557283 @default.
- W2102600963 cites W2030047490 @default.
- W2102600963 cites W2033127827 @default.
- W2102600963 cites W2034037941 @default.
- W2102600963 cites W2036747758 @default.
- W2102600963 cites W2039021795 @default.
- W2102600963 cites W2041847360 @default.
- W2102600963 cites W2041901223 @default.
- W2102600963 cites W2043029684 @default.
- W2102600963 cites W2044248931 @default.
- W2102600963 cites W2045896619 @default.
- W2102600963 cites W2045945078 @default.
- W2102600963 cites W2046850163 @default.
- W2102600963 cites W2047142193 @default.
- W2102600963 cites W2047523002 @default.
- W2102600963 cites W2047820724 @default.
- W2102600963 cites W2048655519 @default.
- W2102600963 cites W2050042714 @default.
- W2102600963 cites W2050892441 @default.
- W2102600963 cites W2052074823 @default.
- W2102600963 cites W2056456647 @default.
- W2102600963 cites W2057162937 @default.
- W2102600963 cites W2059420471 @default.
- W2102600963 cites W2060812839 @default.
- W2102600963 cites W2061055862 @default.
- W2102600963 cites W2063651144 @default.
- W2102600963 cites W2064854818 @default.
- W2102600963 cites W2065707820 @default.
- W2102600963 cites W2066858562 @default.
- W2102600963 cites W2067753015 @default.
- W2102600963 cites W2071480044 @default.
- W2102600963 cites W2074135805 @default.
- W2102600963 cites W2077182680 @default.
- W2102600963 cites W2078575534 @default.
- W2102600963 cites W2081714605 @default.
- W2102600963 cites W2081746977 @default.
- W2102600963 cites W2083045176 @default.
- W2102600963 cites W2083066892 @default.
- W2102600963 cites W2083944461 @default.
- W2102600963 cites W2084762332 @default.