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• W2102612605 endingPage "2151" @default.
• W2102612605 startingPage "2146" @default.
• W2102612605 abstract "Female gerbils fed a diet containing 20% coconut oil develop an intestinal lipodystrophy that is not seen in animals fed a diet containing 20% safflower oil or a diet of 20% coconut oil supplemented with 0.1% inositol. The coconut oil diets contained 1.5% safflower oil to prevent essential fatty acid deficiency. The level of inositol in the intestinal tissue of animals fed the coconut oil diet not supplemented with inositol has been shown to be decreased. Phospholipid analyses of the intestinal tissue were undertaken to determine if this decrease in total inositol was reflected in a decrease in phosphatidylinositol or resulted in an altered phospholipid pattern. No difference in the phosphatidylinositol level was seen between animals fed 20% coconut oil with and without inositol supplementation (µg P/gut section), although animals fed coconut oil diets had lower levels of phosphatidylinositol than animals fed safflower oil diets. Fatty acid analyses of total phospholipid and phosphatidylinositol in gut tissue revealed that animals which developed the lesion had an altered phosphatidylinositol fraction with a depressed level of arachidonic acid and an elevated level of oleic acid. This suggests that the development of the intestinal lipodystrophy may be correlated with qualitative rather than quantitative changes in phosphatidylinositol." @default.
• W2102612605 created "2016-06-24" @default.
• W2102612605 creator A5049581987 @default.
• W2102612605 creator A5072398201 @default.
• W2102612605 date "1979-12-01" @default.
• W2102612605 modified "2023-10-01" @default.
• W2102612605 title "Quantitative and Qualitative Changes in Phospholipid in the Intestine of the Gerbil and the Development of Lipodystrophy" @default.
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• W2102612605 doi "https://doi.org/10.1093/jn/109.12.2146" @default.
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