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- W2102749757 endingPage "1311" @default.
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- W2102749757 abstract "A new method has been developed for the catalytic enantioselective 1,3-dipolar cycloaddition of the Seyferth–Gilbert reagent (SGR) to isatylidene malononitriles using a cinchona alkaloid derivative as a catalyst. This method allowed for the synthesis of a series of chiral spiro-phosphonylpyrazoline-oxindoles in good yields with excellent enantioselectivities. The synthetic utility of this method was further demonstrated by its use in a three-component domino reaction involving isatin, malononitrile, and SGR based on sequential Knoevenagel condensation and 1,3-dipolar cycloaddition reactions." @default.
- W2102749757 created "2016-06-24" @default.
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- W2102749757 date "2015-02-24" @default.
- W2102749757 modified "2023-10-03" @default.
- W2102749757 title "Organocatalytic Enantioselective 1,3-Dipolar Cycloadditions between Seyferth–Gilbert Reagent and Isatylidene Malononitriles: Synthesis of Chiral Spiro-phosphonylpyrazoline-oxindoles" @default.
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- W2102749757 doi "https://doi.org/10.1021/acs.orglett.5b00311" @default.
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