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- W2102779656 abstract "Summary Hepatic hormone hepcidin is a principal regulator of iron homeostasis and a pathogenic factor in common iron disorders. Hepcidin deficiency causes iron overload in hereditary hemochromatosis and iron‐loading anemias, whereas hepcidin excess causes or contributes to the development of iron‐restricted anemia in inflammatory diseases, infections, some cancers, and chronic kidney disease. Because of this, hepcidin may become a useful tool for diagnosis and management of iron disorders. Furthermore, a number of strategies that target hepcidin, its receptor, and its regulators are under development as novel therapeutic approaches for diseases associated with iron dysregulation." @default.
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- W2102779656 date "2015-05-01" @default.
- W2102779656 modified "2023-09-25" @default.
- W2102779656 title "Hepcidin and iron disorders: new biology and clinical approaches" @default.
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- W2102779656 doi "https://doi.org/10.1111/ijlh.12358" @default.
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