FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102793997> ?p ?o ?g. }

• W2102793997 endingPage "343" @default.
• W2102793997 startingPage "338" @default.
• W2102793997 abstract "IntroductionIn addition to emphysema alpha-1-antitrypsin deficiency (AATD) has been shown to be associated with several inflammatory conditions, including bronchiectasis, vasculitis, (in particular Wegener's granulomatosis), and panniculitis, suggesting neutrophil proteinases also play a role in their pathophysiology. However, it remains unknown whether other inflammatory diseases are also more prevalent in AATD than the general population. The current study describes the prevalence of other co-morbidities in AATD with particular emphasis on inflammatory bowel disease.Methods and resultsThe case notes of 651 PiZZ or PiZnull patients attending the UK national centre for AATD between 1996 and 2011 were reviewed. The prevalence of inflammatory bowel disease (1.5%) was higher than that predicted in the UK (0.4%). Ten patients had a confirmed diagnosis of ulcerative colitis, and 1 had Crohn's disease. In 2 cases there was a family history of inflammatory bowel disease and all but 1 patient were ex or never smokers. There was also a higher prevalence of hypothyroidism in this patient group than expected for the UK population – 26 cases (7.2% of females and 1.3% of males).ConclusionsThe current study of the UK cohort of patients with AATD confirmed a higher prevalence of ulcerative colitis than would be expected in the general population, providing further evidence of a potential link between these 2 conditions. In addition, the data suggested a potential link between hypothyroidism and AATD." @default.
• W2102793997 created "2016-06-24" @default.
• W2102793997 creator A5003052401 @default.
• W2102793997 creator A5010056224 @default.
• W2102793997 creator A5051229279 @default.
• W2102793997 date "2014-02-01" @default.
• W2102793997 modified "2023-09-28" @default.
• W2102793997 title "Disease associations in alpha-1-antitrypsin deficiency" @default.
• W2102793997 cites W1493105068 @default.
• W2102793997 cites W168858771 @default.
• W2102793997 cites W1965772763 @default.
• W2102793997 cites W1977861794 @default.
• W2102793997 cites W1979948289 @default.
• W2102793997 cites W1983103020 @default.
• W2102793997 cites W1992270913 @default.
• W2102793997 cites W2005773834 @default.
• W2102793997 cites W2014399192 @default.
• W2102793997 cites W2069931076 @default.
• W2102793997 cites W2097208053 @default.
• W2102793997 cites W2100277531 @default.
• W2102793997 cites W2112912490 @default.
• W2102793997 cites W2143407768 @default.
• W2102793997 cites W2145135012 @default.
• W2102793997 cites W2148113299 @default.
• W2102793997 cites W2148489542 @default.
• W2102793997 cites W2156645716 @default.
• W2102793997 cites W2162929581 @default.
• W2102793997 cites W2170898599 @default.
• W2102793997 cites W4211038572 @default.
• W2102793997 cites W4229485308 @default.
• W2102793997 doi "https://doi.org/10.1016/j.rmed.2013.10.006" @default.
• W2102793997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24176989" @default.
• W2102793997 hasPublicationYear "2014" @default.
• W2102793997 type Work @default.
• W2102793997 sameAs 2102793997 @default.
• W2102793997 citedByCount "43" @default.
• W2102793997 countsByYear W21027939972014 @default.
• W2102793997 countsByYear W21027939972015 @default.
• W2102793997 countsByYear W21027939972016 @default.
• W2102793997 countsByYear W21027939972017 @default.
• W2102793997 countsByYear W21027939972018 @default.
• W2102793997 countsByYear W21027939972019 @default.
• W2102793997 countsByYear W21027939972020 @default.
• W2102793997 countsByYear W21027939972021 @default.
• W2102793997 countsByYear W21027939972022 @default.
• W2102793997 crossrefType "journal-article" @default.
• W2102793997 hasAuthorship W2102793997A5003052401 @default.
• W2102793997 hasAuthorship W2102793997A5010056224 @default.
• W2102793997 hasAuthorship W2102793997A5051229279 @default.
• W2102793997 hasBestOaLocation W21027939971 @default.
• W2102793997 hasConcept C126322002 @default.
• W2102793997 hasConcept C187212893 @default.
• W2102793997 hasConcept C203014093 @default.
• W2102793997 hasConcept C2776015282 @default.
• W2102793997 hasConcept C2777714996 @default.
• W2102793997 hasConcept C2778260677 @default.
• W2102793997 hasConcept C2779134260 @default.
• W2102793997 hasConcept C2779280984 @default.
• W2102793997 hasConcept C2779379686 @default.
• W2102793997 hasConcept C2780479503 @default.
• W2102793997 hasConcept C2780535462 @default.
• W2102793997 hasConcept C2908647359 @default.
• W2102793997 hasConcept C71924100 @default.
• W2102793997 hasConcept C72563966 @default.
• W2102793997 hasConcept C90924648 @default.
• W2102793997 hasConcept C99454951 @default.
• W2102793997 hasConceptScore W2102793997C126322002 @default.
• W2102793997 hasConceptScore W2102793997C187212893 @default.
• W2102793997 hasConceptScore W2102793997C203014093 @default.
• W2102793997 hasConceptScore W2102793997C2776015282 @default.
• W2102793997 hasConceptScore W2102793997C2777714996 @default.
• W2102793997 hasConceptScore W2102793997C2778260677 @default.
• W2102793997 hasConceptScore W2102793997C2779134260 @default.
• W2102793997 hasConceptScore W2102793997C2779280984 @default.
• W2102793997 hasConceptScore W2102793997C2779379686 @default.
• W2102793997 hasConceptScore W2102793997C2780479503 @default.
• W2102793997 hasConceptScore W2102793997C2780535462 @default.
• W2102793997 hasConceptScore W2102793997C2908647359 @default.
• W2102793997 hasConceptScore W2102793997C71924100 @default.
• W2102793997 hasConceptScore W2102793997C72563966 @default.
• W2102793997 hasConceptScore W2102793997C90924648 @default.
• W2102793997 hasConceptScore W2102793997C99454951 @default.
• W2102793997 hasIssue "2" @default.
• W2102793997 hasLocation W21027939971 @default.
• W2102793997 hasLocation W21027939972 @default.
• W2102793997 hasOpenAccess W2102793997 @default.
• W2102793997 hasPrimaryLocation W21027939971 @default.
• W2102793997 hasRelatedWork W1998231725 @default.
• W2102793997 hasRelatedWork W2070285775 @default.
• W2102793997 hasRelatedWork W2124908533 @default.
• W2102793997 hasRelatedWork W2258300052 @default.
• W2102793997 hasRelatedWork W2408939568 @default.
• W2102793997 hasRelatedWork W2409879998 @default.
• W2102793997 hasRelatedWork W2412773332 @default.
• W2102793997 hasRelatedWork W2418837291 @default.
• W2102793997 hasRelatedWork W2512626908 @default.
• W2102793997 hasRelatedWork W46359855 @default.
• W2102793997 hasVolume "108" @default.

• next