FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102800356> ?p ?o ?g. }

• W2102800356 endingPage "3612" @default.
• W2102800356 startingPage "3603" @default.
• W2102800356 abstract "Although decidual natural killer (NK) cell accumulation and vascular remodeling are critical steps to ensure successful pregnancy, the molecular mechanisms controlling these events are poorly defined. Herein we analyzed whether chemerin, a recently identified chemoattractant involved in many pathophysiological processes, could be expressed in the uterine compartment and could regulate events relevant for the good outcome of pregnancy. Chemerin expression in human primary culture of stromal (ST) cells, extravillous trophoblast cells, and decidual endothelial cells (DEC) was analyzed by RT-PCR, ELISA, and Western blot. Migration through ST or DEC of peripheral blood and decidual (d) NK cells from pregnant women was performed using a transwell assay. A DEC capillary-like tube formation assay was used to evaluate endothelial morphogenesis. Chemerin is differentially expressed by decidual cells during early pregnancy being present at high levels in ST and extravillous trophoblast cells but not in DEC. Notably, ST cells from pregnant women exhibit and release higher levels of chemerin as compared with ST cells from menopausal or fertile nonpregnant women. Chemerin can support peripheral blood NK cell migration through both DEC and ST cells. Although dNK cells exhibit lower chemerin receptor (CMKLR1) expression than their blood counterpart, CMKLR1 engagement on dNK cells resulted in both ERK activation and migration through decidual ST cells. Interestingly, DEC also express CMKLR1 and undergo ERK activation and capillary-like tube structure formation upon exposure to chemerin. Our data indicate that chemerin is up-regulated during decidualization and might contribute to NK cell accumulation and vascular remodeling during early pregnancy." @default.
• W2102800356 created "2016-06-24" @default.
• W2102800356 creator A5001539859 @default.
• W2102800356 creator A5007107203 @default.
• W2102800356 creator A5011847088 @default.
• W2102800356 creator A5017694699 @default.
• W2102800356 creator A5024871281 @default.
• W2102800356 creator A5040070739 @default.
• W2102800356 creator A5043026947 @default.
• W2102800356 creator A5048132329 @default.
• W2102800356 creator A5052594030 @default.
• W2102800356 creator A5058039141 @default.
• W2102800356 creator A5063846820 @default.
• W2102800356 creator A5066628297 @default.
• W2102800356 creator A5075247997 @default.
• W2102800356 creator A5086826541 @default.
• W2102800356 creator A5088920406 @default.
• W2102800356 creator A5091151527 @default.
• W2102800356 date "2012-10-01" @default.
• W2102800356 modified "2023-10-16" @default.
• W2102800356 title "Chemerin Regulates NK Cell Accumulation and Endothelial Cell Morphogenesis in the Decidua during Early Pregnancy" @default.
• W2102800356 cites W1496091321 @default.
• W2102800356 cites W1568924129 @default.
• W2102800356 cites W1638418641 @default.
• W2102800356 cites W1968846807 @default.
• W2102800356 cites W1973951521 @default.
• W2102800356 cites W1986082361 @default.
• W2102800356 cites W1987267883 @default.
• W2102800356 cites W2004979729 @default.
• W2102800356 cites W2011407381 @default.
• W2102800356 cites W2013971421 @default.
• W2102800356 cites W2024299100 @default.
• W2102800356 cites W2026445106 @default.
• W2102800356 cites W2026884886 @default.
• W2102800356 cites W2031265178 @default.
• W2102800356 cites W2040538270 @default.
• W2102800356 cites W2052222318 @default.
• W2102800356 cites W2067132234 @default.
• W2102800356 cites W2075787203 @default.
• W2102800356 cites W2080838055 @default.
• W2102800356 cites W2083441410 @default.
• W2102800356 cites W2085615839 @default.
• W2102800356 cites W2086335340 @default.
• W2102800356 cites W2091671016 @default.
• W2102800356 cites W2093060517 @default.
• W2102800356 cites W2093227175 @default.
• W2102800356 cites W2095056898 @default.
• W2102800356 cites W2099243764 @default.
• W2102800356 cites W2106939328 @default.
• W2102800356 cites W2107652077 @default.
• W2102800356 cites W2112160387 @default.
• W2102800356 cites W2119773094 @default.
• W2102800356 cites W2120067155 @default.
• W2102800356 cites W2120798610 @default.
• W2102800356 cites W2122523355 @default.
• W2102800356 cites W2124537691 @default.
• W2102800356 cites W2127594017 @default.
• W2102800356 cites W2132767601 @default.
• W2102800356 cites W2133490741 @default.
• W2102800356 cites W2161903740 @default.
• W2102800356 cites W2162646944 @default.
• W2102800356 cites W2164424072 @default.
• W2102800356 cites W2166898983 @default.
• W2102800356 cites W2168015220 @default.
• W2102800356 cites W2168026517 @default.
• W2102800356 cites W2204640292 @default.
• W2102800356 cites W2335394363 @default.
• W2102800356 doi "https://doi.org/10.1210/jc.2012-1102" @default.
• W2102800356 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3462933" @default.
• W2102800356 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22791765" @default.
• W2102800356 hasPublicationYear "2012" @default.
• W2102800356 type Work @default.
• W2102800356 sameAs 2102800356 @default.
• W2102800356 citedByCount "70" @default.
• W2102800356 countsByYear W21028003562013 @default.
• W2102800356 countsByYear W21028003562014 @default.
• W2102800356 countsByYear W21028003562015 @default.
• W2102800356 countsByYear W21028003562016 @default.
• W2102800356 countsByYear W21028003562017 @default.
• W2102800356 countsByYear W21028003562018 @default.
• W2102800356 countsByYear W21028003562019 @default.
• W2102800356 countsByYear W21028003562020 @default.
• W2102800356 countsByYear W21028003562021 @default.
• W2102800356 countsByYear W21028003562022 @default.
• W2102800356 countsByYear W21028003562023 @default.
• W2102800356 crossrefType "journal-article" @default.
• W2102800356 hasAuthorship W2102800356A5001539859 @default.
• W2102800356 hasAuthorship W2102800356A5007107203 @default.
• W2102800356 hasAuthorship W2102800356A5011847088 @default.
• W2102800356 hasAuthorship W2102800356A5017694699 @default.
• W2102800356 hasAuthorship W2102800356A5024871281 @default.
• W2102800356 hasAuthorship W2102800356A5040070739 @default.
• W2102800356 hasAuthorship W2102800356A5043026947 @default.
• W2102800356 hasAuthorship W2102800356A5048132329 @default.
• W2102800356 hasAuthorship W2102800356A5052594030 @default.
• W2102800356 hasAuthorship W2102800356A5058039141 @default.
• W2102800356 hasAuthorship W2102800356A5063846820 @default.
• W2102800356 hasAuthorship W2102800356A5066628297 @default.

• next