FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102843335> ?p ?o ?g. }

• W2102843335 endingPage "12307" @default.
• W2102843335 startingPage "12297" @default.
• W2102843335 abstract "Adenoviruses (Ads) encode several proteins within the early region 3 (E3) transcription unit that help protect infected cells from elimination by the immune system. Among these immunomodulatory proteins, the receptor internalization and degradation (RID) protein complex, which is composed of the RIDalpha (formerly E3-10.4K) and RIDbeta (formerly E3-14.5K) subunits, stimulates the internalization and degradation of certain members of the tumor necrosis factor (TNF) receptor superfamily, thus blocking apoptosis initiated by Fas and TNF-related apoptosis-inducing ligand (TRAIL). The experiments reported here show that TRAIL receptor 2 (TR2) is cleared from the cell surface in Ad-infected cells. Virus mutants containing deletions that span E3 were used to show that the RID and E3-6.7K proteins are both necessary for the internalization and degradation of TR2, whereas only the RID protein is required for TRAIL receptor 1 downregulation. In addition, replication-defective Ad vectors that express individual E3 proteins were used to establish that the RID and E3-6.7K proteins are sufficient to clear TR2. These data demonstrate that E3-6.7K is an important component of the antiapoptosis arsenal encoded by the E3 transcription unit of subgroup C Ads." @default.
• W2102843335 created "2016-06-24" @default.
• W2102843335 creator A5009194049 @default.
• W2102843335 creator A5030143515 @default.
• W2102843335 creator A5032387026 @default.
• W2102843335 creator A5074721194 @default.
• W2102843335 creator A5075189401 @default.
• W2102843335 creator A5081236075 @default.
• W2102843335 date "2004-11-15" @default.
• W2102843335 modified "2023-10-18" @default.
• W2102843335 title "Adenovirus E3-6.7K Protein Is Required in Conjunction with the E3-RID Protein Complex for the Internalization and Degradation of TRAIL Receptor 2" @default.
• W2102843335 cites W117595245 @default.
• W2102843335 cites W1251295525 @default.
• W2102843335 cites W1486479332 @default.
• W2102843335 cites W1506671456 @default.
• W2102843335 cites W1515226983 @default.
• W2102843335 cites W1540388172 @default.
• W2102843335 cites W1565773781 @default.
• W2102843335 cites W1618992081 @default.
• W2102843335 cites W1625560485 @default.
• W2102843335 cites W1826224336 @default.
• W2102843335 cites W1924062135 @default.
• W2102843335 cites W1965358648 @default.
• W2102843335 cites W1966498008 @default.
• W2102843335 cites W1978306626 @default.
• W2102843335 cites W1980185531 @default.
• W2102843335 cites W1983303434 @default.
• W2102843335 cites W1986772433 @default.
• W2102843335 cites W2012658992 @default.
• W2102843335 cites W2026351218 @default.
• W2102843335 cites W2028302056 @default.
• W2102843335 cites W2032345713 @default.
• W2102843335 cites W2045652278 @default.
• W2102843335 cites W2049021232 @default.
• W2102843335 cites W2056217426 @default.
• W2102843335 cites W2057698452 @default.
• W2102843335 cites W2061380671 @default.
• W2102843335 cites W2066780628 @default.
• W2102843335 cites W2070596285 @default.
• W2102843335 cites W2079263000 @default.
• W2102843335 cites W2084244793 @default.
• W2102843335 cites W2091792783 @default.
• W2102843335 cites W2097238022 @default.
• W2102843335 cites W2099287214 @default.
• W2102843335 cites W2102626689 @default.
• W2102843335 cites W2107962824 @default.
• W2102843335 cites W2111950267 @default.
• W2102843335 cites W2115668720 @default.
• W2102843335 cites W2116951270 @default.
• W2102843335 cites W2120139387 @default.
• W2102843335 cites W2125649379 @default.
• W2102843335 cites W2130988210 @default.
• W2102843335 cites W2133210732 @default.
• W2102843335 cites W2141165130 @default.
• W2102843335 cites W2158547369 @default.
• W2102843335 cites W2163010298 @default.
• W2102843335 cites W2164609914 @default.
• W2102843335 cites W2167645877 @default.
• W2102843335 cites W2170197058 @default.
• W2102843335 cites W80071992 @default.
• W2102843335 doi "https://doi.org/10.1128/jvi.78.22.12297-12307.2004" @default.
• W2102843335 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/525093" @default.
• W2102843335 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15507617" @default.
• W2102843335 hasPublicationYear "2004" @default.
• W2102843335 type Work @default.
• W2102843335 sameAs 2102843335 @default.
• W2102843335 citedByCount "36" @default.
• W2102843335 countsByYear W21028433352012 @default.
• W2102843335 countsByYear W21028433352013 @default.
• W2102843335 countsByYear W21028433352014 @default.
• W2102843335 countsByYear W21028433352015 @default.
• W2102843335 countsByYear W21028433352016 @default.
• W2102843335 countsByYear W21028433352017 @default.
• W2102843335 countsByYear W21028433352018 @default.
• W2102843335 countsByYear W21028433352019 @default.
• W2102843335 countsByYear W21028433352021 @default.
• W2102843335 countsByYear W21028433352022 @default.
• W2102843335 crossrefType "journal-article" @default.
• W2102843335 hasAuthorship W2102843335A5009194049 @default.
• W2102843335 hasAuthorship W2102843335A5030143515 @default.
• W2102843335 hasAuthorship W2102843335A5032387026 @default.
• W2102843335 hasAuthorship W2102843335A5074721194 @default.
• W2102843335 hasAuthorship W2102843335A5075189401 @default.
• W2102843335 hasAuthorship W2102843335A5081236075 @default.
• W2102843335 hasBestOaLocation W21028433351 @default.
• W2102843335 hasConcept C104317684 @default.
• W2102843335 hasConcept C127561419 @default.
• W2102843335 hasConcept C139770010 @default.
• W2102843335 hasConcept C153911025 @default.
• W2102843335 hasConcept C159047783 @default.
• W2102843335 hasConcept C170493617 @default.
• W2102843335 hasConcept C54355233 @default.
• W2102843335 hasConcept C86339819 @default.
• W2102843335 hasConcept C86803240 @default.
• W2102843335 hasConcept C95444343 @default.
• W2102843335 hasConceptScore W2102843335C104317684 @default.
• W2102843335 hasConceptScore W2102843335C127561419 @default.
• W2102843335 hasConceptScore W2102843335C139770010 @default.

• next