FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102862738> ?p ?o ?g. }

• W2102862738 endingPage "130" @default.
• W2102862738 startingPage "126" @default.
• W2102862738 abstract "<b>Aim:</b> To survey the investigation of short stature in Wales and suggest guidelines to improve practice. <b>Methods:</b> Questionnaires were circulated to paediatricians and consultant clinical biochemists or consultant chemical pathologists at 13 Welsh hospitals where children with short stature are investigated. <b>Results:</b> A 100% response was obtained from laboratory and clinical staff. Clinicians screened 1–50 patients each year (median, 10). Growth hormone (GH) deficiency was subsequently diagnosed in 0–30% (median, 10%) and GH treatment started in 30–100% (median, 100%) of patients. Five paediatricians and eight laboratories had written investigative protocols. Investigation of GH secretion was initiated in some centres before a complete clinical evaluation was carried out. Various screening tests for GH deficiency, including insulin-like growth factor 1 (IGF-1), random GH, and exercise tests were used. The clonidine stimulation test was used to assess the GH axis in most centres but eight different protocols were described. GH was measured in four Welsh laboratories using two automated immunoassay methods. However, nine different ranges of cutoff values for defining abnormal GH responses were quoted, and in three centres laboratories and paediatricians quoted different cutoffs. <b>Conclusion:</b> This survey demonstrates the need for practical guidelines for the investigation and management of short stature in children, agreed by paediatricians and their laboratory colleagues. The guidelines should encompass the initial clinical investigation, assessment of the GH–IGF-1 axis (using standardised protocols), and provision for the transition to adult management. This article presents practical guidelines based on published points for good practice." @default.
• W2102862738 created "2016-06-24" @default.
• W2102862738 creator A5050719368 @default.
• W2102862738 creator A5068658241 @default.
• W2102862738 date "2004-02-01" @default.
• W2102862738 modified "2023-10-01" @default.
• W2102862738 title "The investigation of short stature: a survey of practice in Wales and suggested practical guidelines" @default.
• W2102862738 cites W1965200692 @default.
• W2102862738 cites W1983984026 @default.
• W2102862738 cites W2017275370 @default.
• W2102862738 cites W2041816385 @default.
• W2102862738 cites W2059093854 @default.
• W2102862738 cites W2065087499 @default.
• W2102862738 cites W2148389327 @default.
• W2102862738 cites W4240877614 @default.
• W2102862738 cites W4254451072 @default.
• W2102862738 doi "https://doi.org/10.1136/jcp.2002.002238" @default.
• W2102862738 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1770205" @default.
• W2102862738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14747433" @default.
• W2102862738 hasPublicationYear "2004" @default.
• W2102862738 type Work @default.
• W2102862738 sameAs 2102862738 @default.
• W2102862738 citedByCount "15" @default.
• W2102862738 countsByYear W21028627382015 @default.
• W2102862738 countsByYear W21028627382016 @default.
• W2102862738 countsByYear W21028627382019 @default.
• W2102862738 countsByYear W21028627382021 @default.
• W2102862738 countsByYear W21028627382023 @default.
• W2102862738 crossrefType "journal-article" @default.
• W2102862738 hasAuthorship W2102862738A5050719368 @default.
• W2102862738 hasAuthorship W2102862738A5068658241 @default.
• W2102862738 hasBestOaLocation W21028627381 @default.
• W2102862738 hasConcept C126322002 @default.
• W2102862738 hasConcept C138885662 @default.
• W2102862738 hasConcept C187212893 @default.
• W2102862738 hasConcept C2777871287 @default.
• W2102862738 hasConcept C2778399450 @default.
• W2102862738 hasConcept C2778754045 @default.
• W2102862738 hasConcept C2779952775 @default.
• W2102862738 hasConcept C2780769345 @default.
• W2102862738 hasConcept C2984496839 @default.
• W2102862738 hasConcept C41895202 @default.
• W2102862738 hasConcept C512399662 @default.
• W2102862738 hasConcept C71315377 @default.
• W2102862738 hasConcept C71924100 @default.
• W2102862738 hasConceptScore W2102862738C126322002 @default.
• W2102862738 hasConceptScore W2102862738C138885662 @default.
• W2102862738 hasConceptScore W2102862738C187212893 @default.
• W2102862738 hasConceptScore W2102862738C2777871287 @default.
• W2102862738 hasConceptScore W2102862738C2778399450 @default.
• W2102862738 hasConceptScore W2102862738C2778754045 @default.
• W2102862738 hasConceptScore W2102862738C2779952775 @default.
• W2102862738 hasConceptScore W2102862738C2780769345 @default.
• W2102862738 hasConceptScore W2102862738C2984496839 @default.
• W2102862738 hasConceptScore W2102862738C41895202 @default.
• W2102862738 hasConceptScore W2102862738C512399662 @default.
• W2102862738 hasConceptScore W2102862738C71315377 @default.
• W2102862738 hasConceptScore W2102862738C71924100 @default.
• W2102862738 hasIssue "2" @default.
• W2102862738 hasLocation W21028627381 @default.
• W2102862738 hasLocation W21028627382 @default.
• W2102862738 hasLocation W21028627383 @default.
• W2102862738 hasLocation W21028627384 @default.
• W2102862738 hasOpenAccess W2102862738 @default.
• W2102862738 hasPrimaryLocation W21028627381 @default.
• W2102862738 hasRelatedWork W1973807070 @default.
• W2102862738 hasRelatedWork W2004658946 @default.
• W2102862738 hasRelatedWork W2024134218 @default.
• W2102862738 hasRelatedWork W2254556899 @default.
• W2102862738 hasRelatedWork W2340668094 @default.
• W2102862738 hasRelatedWork W2766969746 @default.
• W2102862738 hasRelatedWork W3029381211 @default.
• W2102862738 hasRelatedWork W4238961491 @default.
• W2102862738 hasRelatedWork W4311090575 @default.
• W2102862738 hasRelatedWork W49358886 @default.
• W2102862738 hasVolume "57" @default.
• W2102862738 isParatext "false" @default.
• W2102862738 isRetracted "false" @default.
• W2102862738 magId "2102862738" @default.
• W2102862738 workType "article" @default.