FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102933766> ?p ?o ?g. }

• W2102933766 abstract "Abstract This chapter reviews statistical methods for detecting adaptive molecular evolution by comparing synonymous and non‐synonymous substitution rates in protein‐coding DNA sequences. A Markov process model of codon substitution is introduced first, which forms the basis for all later discussions in this chapter. I then consider the case of comparing two sequences to estimate the numbers of synonymous ( d S ) and non‐synonymous ( d N ) substitutions per site. The maximum likelihood (ML) method and a number of ad hoc counting methods are evaluated. The rest of the chapter deals with joint analyses of multiple sequences on a phylogeny. I review Markov models of codon substitution that allow the non‐synonymous/synonymous rate ratio to vary among branches in a phylogeny or among amino acid sites in a protein. Those models can be used to construct likelihood ratio tests to identify evolutionary lineages under episodic Darwinian selection or to infer critical amino acids in a protein under diversifying selection. I use real data examples to demonstrate the application of the methods. The chapter finishes with a discussion of the limitations of current methods." @default.
• W2102933766 created "2016-06-24" @default.
• W2102933766 creator A5073515441 @default.
• W2102933766 date "2003-07-22" @default.
• W2102933766 modified "2023-10-12" @default.
• W2102933766 title "Adaptive Molecular Evolution" @default.
• W2102933766 cites W1514792623 @default.
• W2102933766 cites W1525734744 @default.
• W2102933766 cites W1555986815 @default.
• W2102933766 cites W1610664511 @default.
• W2102933766 cites W1921179170 @default.
• W2102933766 cites W1968248848 @default.
• W2102933766 cites W1968882642 @default.
• W2102933766 cites W1974017602 @default.
• W2102933766 cites W1987510089 @default.
• W2102933766 cites W1990058505 @default.
• W2102933766 cites W1990157150 @default.
• W2102933766 cites W1993054962 @default.
• W2102933766 cites W1997012028 @default.
• W2102933766 cites W1997170579 @default.
• W2102933766 cites W2007325254 @default.
• W2102933766 cites W2026551295 @default.
• W2102933766 cites W2029353325 @default.
• W2102933766 cites W2029549914 @default.
• W2102933766 cites W2035472290 @default.
• W2102933766 cites W2039950438 @default.
• W2102933766 cites W2042601802 @default.
• W2102933766 cites W2047213918 @default.
• W2102933766 cites W2048541401 @default.
• W2102933766 cites W2050120307 @default.
• W2102933766 cites W2056384440 @default.
• W2102933766 cites W2057456873 @default.
• W2102933766 cites W2057538311 @default.
• W2102933766 cites W2061819685 @default.
• W2102933766 cites W2063034269 @default.
• W2102933766 cites W2067207399 @default.
• W2102933766 cites W2071537172 @default.
• W2102933766 cites W2086528371 @default.
• W2102933766 cites W2088012478 @default.
• W2102933766 cites W2088091848 @default.
• W2102933766 cites W2093246625 @default.
• W2102933766 cites W2094123729 @default.
• W2102933766 cites W2101183221 @default.
• W2102933766 cites W2102424972 @default.
• W2102933766 cites W2105585336 @default.
• W2102933766 cites W2111762123 @default.
• W2102933766 cites W2114828923 @default.
• W2102933766 cites W2115011276 @default.
• W2102933766 cites W2116111392 @default.
• W2102933766 cites W2131351884 @default.
• W2102933766 cites W2133585817 @default.
• W2102933766 cites W2137426528 @default.
• W2102933766 cites W2141201180 @default.
• W2102933766 cites W2144368480 @default.
• W2102933766 cites W2146058442 @default.
• W2102933766 cites W2152873040 @default.
• W2102933766 cites W2155761127 @default.
• W2102933766 cites W2155836971 @default.
• W2102933766 cites W2156434383 @default.
• W2102933766 cites W2157847015 @default.
• W2102933766 cites W2160364329 @default.
• W2102933766 cites W2160714946 @default.
• W2102933766 cites W2162250327 @default.
• W2102933766 cites W2179885821 @default.
• W2102933766 cites W3012079654 @default.
• W2102933766 cites W4254717640 @default.
• W2102933766 cites W4319783519 @default.
• W2102933766 doi "https://doi.org/10.1002/0470022620.bbc10" @default.
• W2102933766 hasPublicationYear "2003" @default.
• W2102933766 type Work @default.
• W2102933766 sameAs 2102933766 @default.
• W2102933766 citedByCount "4" @default.
• W2102933766 countsByYear W21029337662012 @default.
• W2102933766 countsByYear W21029337662013 @default.
• W2102933766 countsByYear W21029337662016 @default.
• W2102933766 crossrefType "other" @default.
• W2102933766 hasAuthorship W2102933766A5073515441 @default.
• W2102933766 hasConcept C104317684 @default.
• W2102933766 hasConcept C119857082 @default.
• W2102933766 hasConcept C138025448 @default.
• W2102933766 hasConcept C141231307 @default.
• W2102933766 hasConcept C154945302 @default.
• W2102933766 hasConcept C166393388 @default.
• W2102933766 hasConcept C199360897 @default.
• W2102933766 hasConcept C2778220771 @default.
• W2102933766 hasConcept C2993683473 @default.
• W2102933766 hasConcept C41008148 @default.
• W2102933766 hasConcept C501734568 @default.
• W2102933766 hasConcept C54355233 @default.
• W2102933766 hasConcept C70721500 @default.
• W2102933766 hasConcept C78458016 @default.
• W2102933766 hasConcept C81917197 @default.
• W2102933766 hasConcept C86803240 @default.
• W2102933766 hasConcept C87253356 @default.
• W2102933766 hasConcept C90132467 @default.
• W2102933766 hasConcept C98763669 @default.
• W2102933766 hasConceptScore W2102933766C104317684 @default.
• W2102933766 hasConceptScore W2102933766C119857082 @default.
• W2102933766 hasConceptScore W2102933766C138025448 @default.
• W2102933766 hasConceptScore W2102933766C141231307 @default.

• next