Matches in SemOpenAlex for { <https://semopenalex.org/work/W2102975934> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2102975934 endingPage "42" @default.
- W2102975934 startingPage "35" @default.
- W2102975934 abstract "To study adrenal crisis (AC) in patients with congenital adrenal hyperplasia due to classical 21-hydroxylase deficiency (21-OHD). AC was defined as an acute state of health impairment requiring i.v. glucocorticoid administration and hospital admission.In a cross-sectional study with detailed retrospective assessment, AC was studied following two approaches: i) questionnaire based: 122 adult 21-OHD patients (50 men, 72 women, median age 35 years, range 18-69 years) completed a disease-specific questionnaire; and ii) patient chart based: charts of 67 21-OHD patients (32 males, 35 females, median age 31 years, range 20-66 years) were analyzed from diagnosis to last follow-up with regard to frequency and causes of AC since diagnosis.Evaluation of questionnaires revealed 257 ACs in 4456 patient years (py; frequency 5.8 crises/100 py), while patient charts documented 106 ACs in 2181 py (4.9 crises/100 py). The chart-based evaluation showed that gastrointestinal infections (29%) and salt-wasting crisis (18%) were the main causes of AC. In 14%, the cause remained uncertain. There was no difference in the overall frequency of AC in males and females. AC mostly occurred during childhood, with more than 70% of AC in the first 10 years of life and one-third of AC in the first year of life. Still, 20% of cases of AC were observed in adults (>18 years).Our data demonstrate a significant risk of AC in patients with 21-OHD over lifetime. Specific age-adapted and repeated crisis prevention training may help to reduce morbidity due to AC in 21-OHD." @default.
- W2102975934 created "2016-06-24" @default.
- W2102975934 creator A5014771501 @default.
- W2102975934 creator A5017793957 @default.
- W2102975934 creator A5038989241 @default.
- W2102975934 creator A5052776295 @default.
- W2102975934 creator A5057631300 @default.
- W2102975934 creator A5067807307 @default.
- W2102975934 creator A5083625945 @default.
- W2102975934 creator A5087620820 @default.
- W2102975934 creator A5090695853 @default.
- W2102975934 date "2012-04-18" @default.
- W2102975934 modified "2023-10-15" @default.
- W2102975934 title "Frequency and causes of adrenal crises over lifetime in patients with 21-hydroxylase deficiency" @default.
- W2102975934 cites W1965015029 @default.
- W2102975934 cites W1972087695 @default.
- W2102975934 cites W1980748985 @default.
- W2102975934 cites W1995900346 @default.
- W2102975934 cites W2010100823 @default.
- W2102975934 cites W2013908767 @default.
- W2102975934 cites W2044722834 @default.
- W2102975934 cites W2048145710 @default.
- W2102975934 cites W2056009852 @default.
- W2102975934 cites W2072801118 @default.
- W2102975934 cites W2087687474 @default.
- W2102975934 cites W2113107736 @default.
- W2102975934 cites W2148763233 @default.
- W2102975934 cites W4211192934 @default.
- W2102975934 cites W4245214929 @default.
- W2102975934 cites W4248171562 @default.
- W2102975934 cites W4251903652 @default.
- W2102975934 cites W4376848764 @default.
- W2102975934 doi "https://doi.org/10.1530/eje-12-0161" @default.
- W2102975934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22513882" @default.
- W2102975934 hasPublicationYear "2012" @default.
- W2102975934 type Work @default.
- W2102975934 sameAs 2102975934 @default.
- W2102975934 citedByCount "102" @default.
- W2102975934 countsByYear W21029759342012 @default.
- W2102975934 countsByYear W21029759342013 @default.
- W2102975934 countsByYear W21029759342014 @default.
- W2102975934 countsByYear W21029759342015 @default.
- W2102975934 countsByYear W21029759342016 @default.
- W2102975934 countsByYear W21029759342017 @default.
- W2102975934 countsByYear W21029759342018 @default.
- W2102975934 countsByYear W21029759342019 @default.
- W2102975934 countsByYear W21029759342020 @default.
- W2102975934 countsByYear W21029759342021 @default.
- W2102975934 countsByYear W21029759342022 @default.
- W2102975934 countsByYear W21029759342023 @default.
- W2102975934 crossrefType "journal-article" @default.
- W2102975934 hasAuthorship W2102975934A5014771501 @default.
- W2102975934 hasAuthorship W2102975934A5017793957 @default.
- W2102975934 hasAuthorship W2102975934A5038989241 @default.
- W2102975934 hasAuthorship W2102975934A5052776295 @default.
- W2102975934 hasAuthorship W2102975934A5057631300 @default.
- W2102975934 hasAuthorship W2102975934A5067807307 @default.
- W2102975934 hasAuthorship W2102975934A5083625945 @default.
- W2102975934 hasAuthorship W2102975934A5087620820 @default.
- W2102975934 hasAuthorship W2102975934A5090695853 @default.
- W2102975934 hasBestOaLocation W21029759341 @default.
- W2102975934 hasConcept C126322002 @default.
- W2102975934 hasConcept C187212893 @default.
- W2102975934 hasConcept C2777767042 @default.
- W2102975934 hasConcept C2778129406 @default.
- W2102975934 hasConcept C2778808452 @default.
- W2102975934 hasConcept C2780321258 @default.
- W2102975934 hasConcept C2780841215 @default.
- W2102975934 hasConcept C71924100 @default.
- W2102975934 hasConceptScore W2102975934C126322002 @default.
- W2102975934 hasConceptScore W2102975934C187212893 @default.
- W2102975934 hasConceptScore W2102975934C2777767042 @default.
- W2102975934 hasConceptScore W2102975934C2778129406 @default.
- W2102975934 hasConceptScore W2102975934C2778808452 @default.
- W2102975934 hasConceptScore W2102975934C2780321258 @default.
- W2102975934 hasConceptScore W2102975934C2780841215 @default.
- W2102975934 hasConceptScore W2102975934C71924100 @default.
- W2102975934 hasIssue "1" @default.
- W2102975934 hasLocation W21029759341 @default.
- W2102975934 hasLocation W21029759342 @default.
- W2102975934 hasOpenAccess W2102975934 @default.
- W2102975934 hasPrimaryLocation W21029759341 @default.
- W2102975934 hasRelatedWork W1991990426 @default.
- W2102975934 hasRelatedWork W1992240692 @default.
- W2102975934 hasRelatedWork W2087765991 @default.
- W2102975934 hasRelatedWork W2623057639 @default.
- W2102975934 hasRelatedWork W2738473478 @default.
- W2102975934 hasRelatedWork W3031029826 @default.
- W2102975934 hasRelatedWork W3043068155 @default.
- W2102975934 hasRelatedWork W4220908679 @default.
- W2102975934 hasRelatedWork W4296921826 @default.
- W2102975934 hasRelatedWork W4308005574 @default.
- W2102975934 hasVolume "167" @default.
- W2102975934 isParatext "false" @default.
- W2102975934 isRetracted "false" @default.
- W2102975934 magId "2102975934" @default.
- W2102975934 workType "article" @default.